Jeff Lee
@jefflee1103
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Researcher @ilandavislab University of Glasgow. RNA biology | Brain development | Viruses.
Glasgow, Scotland
Joined May 2010
Following our recent publication, here’s a striking collage of developing fly brain! 🧠✨ Highlighting the dynamic expression of RNA-binding proteins Imp (green) and Syp (magenta) https://t.co/zCqJzAyUH3
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@ScienceAdvances @ilandavislab Grateful to Niles, Tamsin, @ilandavis, and our amazing collaborators for their support in this journey! 🙌
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🧠🔬How do RNA-binding proteins shape brain development? Our latest study reveals how Imp & Syp form combinatorial networks to regulate Drosophila neurogenesis. Excited to share this work in @ScienceAdvances! 📜 Read more: https://t.co/zCqJzAymRv
@ilandavislab #RNA #neurogenesis
science.org
RNA binding protein combinations control neuronal identity through a network of temporal regulators.
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New publication from @castello_lab and @FranklinSystems in @MolecularCell 🚨🚨🚨! We discover a group of nuclear #RBPs that travel to the cytoplasm to inhibit #virus #infection. We discover a novel #RNA mediated antiviral mechanism mediated by the U2snRNP
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: 🚀 Exciting News! Our latest review, “Exploring the expanding universe of host-virus interactions mediated by viral RNA,” is now published in the Molecular Cell issue focused on RNA! 🌟. #RNA, #virus, @CVRinfo , @embl
https://t.co/YMv0Wg2nP9
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Excited to announce our latest publication by Julia Olivares-Abril et al.! 🎉 This study introduces innovative techniques for high-resolution RNA imaging in Drosophila larvae. Explore the full paper here: https://t.co/QPLZqTBtCm 🧬 #RNAImaging #Drosophila #MolecularBiology
tandfonline.com
In situ hybridization techniques are powerful methods for exploring gene expression in a wide range of biological contexts, providing spatial information that is most often lost in traditional bioc...
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Latest paper from our lab looking at glial protrusion localised RNAs is now online at JCB! @ilandavislab
.@jefflee1103, Gala, @ilandavis @ilandavislab & colleagues identified conserved disease-associated mRNAs localized to glial projections and required specifically in #glia for synapse formation in their adjacent #neurons. https://t.co/A1vMFhijOY
#neuroscience
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Pleased to share our latest work on how RNA-binding proteins regulate brain development on #bioRxiv 🧠🔬🪰 @ilandavislab @TamsinJSamuels
Imp and Syp in vivo temporal RNA interactomes uncover networks of temporal regulators of Drosophila brain development. https://t.co/rXbPwIWLZg
#bioRxiv
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We have a job opening: We are looking for a postdoc to work on RNA and glial biology in flies. It's a 2 year post to use ground breaking tech to study post-transcriptional regulation. More information and apply at: https://t.co/6sJdGckpgT
#sciencejobs
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It has been 7 years since I first fell in love with the beauty of the fruit fly. Now I hope to convince you all with these amazing images created using spatial transcriptomics on whole head and whole fly(!) samples! Biorxiv ( https://t.co/fjNYdCnIhc) or https://t.co/IWa5QTQRio 🧵
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Proud to be involved with this work particularly after its long gestation period! @castello_lab
@ilandavislab
https://t.co/S1WLyLPYVl
biorxiv.org
The initial steps of the human immunodeficiency virus 1 (HIV-1) lifecycle are regulated by cellular RNA-binding proteins (RBPs). To understand the scope of these early host-virus interactions, we...
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New preprint from @castello_lab!! Happy to have been involved in this fantastic work! @ilandavislab
New preprint from the @castello_lab, showing that #HIV packages its genome with over 100 cellular #RBPs into viral particles. These proteins can play critical roles, e.g., PURA and PURB binds to key elements in HIV genome and enhances virion infectivity
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Collage of developing #fruitfly #brains – fluorescently-tagged proteins localised throughout the central nervous system. Image by @jefflee1103 2nd place in @BiochemOxford Centenary Science Imaging Competition. More on https://t.co/oJbmruSTbt with @MRC_LMS & @DrJohnAnkers
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A video abstract of our latest paper published in @JCellBiol . For more information please visit https://t.co/vST0TxCRQ0 and we are happy to take any questions. A plain English version for non-scientists coming soon
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After a LOT of work, our latest paper is out in @JCellBiol today. A screen of 200 genes throughout the fly nervous system shows post-transcriptional regulation is the rule rather than the exception. Video abstract and plain English explanations next week
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Authors include: @Uraeus_Nefer
@ilandavis
@bones_giles
@snthornton29
@kiourlappou
@jefflee1103
@dalia_science
@carandraugNet
@AinoJarvelin
A screen of 200 genes to single molecule resolution finds that discordance between location of mRNA and protein is common in the nervous system of #Drosophila. https://t.co/a5gvgejFUP Contact @ilandavislab to discuss, images and metadata available here: https://t.co/9ueOBdzZ3t
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A screen of 200 genes to single molecule resolution finds that discordance between location of mRNA and protein is common in the nervous system of #Drosophila. https://t.co/a5gvgejFUP Contact @ilandavislab to discuss, images and metadata available here: https://t.co/9ueOBdzZ3t
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Come work with us. A 5-year postdoc has opened up for a Viral RNA Biologist with advanced imaging experience. Part of a large collaborative team with @McKeatingLab and Fadi Issa's lab, we aim to better understand the molecular mechanisms behind chronic Hepatitis B infection. 1/2
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