Gene Regulation
@generegulation
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Gene regulation community. #chromatin #nucleosome #TFbinding #CTCF #cancer #epigenetics. Personal views do not represent @TeifLab. Mostly moved to 🦋 and 🐘
London, UK
Joined January 2013
RT @ElenaPugachev12: Excited to share our latest study published in Nucleic Acids Research: It’s the cover story fo….
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RT @anshulkundaje: @sara_mostafavi (@genentech ) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with dee….
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RT @sroyyors: Perspective on recent developments and challenges in regulatory and systems genomics is out, amazing….
academic.oup.com
Abstract. Summary: Predicting how genetic variation affects phenotypic outcomes at the organismal, cellular, and molecular levels requires deciphering the
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RT @TeifLab: We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to wo….
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RT @DafneDiGiammart: I am so happy to see this work finally out 🎉 Thanks to all the authors for the incredible te….
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RT @mikhailspivakov: ❤️🔥 Passionate about gene regulation research, wet/dry lab? .🎡 Excited about London's vibrant research and social s….
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RT @MasaAShimazoe: My first, first author paper is now on bioRxiv! 🤩. Linker histone H1 is a liquid-like "glue" condensing chromatin, which….
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RT @molbiosystems: 🚨 Registration for the Molecular Biosystems Conference is now OPEN! . Join us to discuss cutting-edge research in gene r….
molbiosystems.com
Leading Latin American conference on Eukaryotic Gene Regulation & Functional Genomics.
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RT @TeifLab: Very happy to contribute to this paper about cfDNA in SCLC, led by the team of Anish Thomas. It's already online in Genome Med….
genomemedicine.biomedcentral.com
Background Profiling circulating cell-free DNA (cfDNA) has become a fundamental practice in cancer medicine, but the effectiveness of cfDNA at elucidating tumor-derived molecular features has not...
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RT @surabhi_txn: Our latest preprint on emergent #3Dgenome reorganization from the stepwise assembly of the #transcriptional #condensates.….
biorxiv.org
Transcriptional condensates are clusters of transcription factors, coactivators, and RNA Pol II associated with high-level gene expression, yet how they assemble and function within the cell remains...
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RT @sheeradar: New paper alert! The epigenetic landscape shapes smoking-induced mutagenesis by modulating DNA damage susceptibility and DNA….
academic.oup.com
Abstract. Lung cancer sequencing efforts have uncovered mutational signatures that are attributed to exposure to the cigarette smoke carcinogen benzo[a]pyr
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RT @PradeepMadapura: We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics….
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RT @OdedRechavi: IT'S HAPPENING! The Woodstock of Biology 2.0 meets Night Science @nightsciencepod .10-13 of June in Prague & the Woods of….
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RT @Chromozz: Our new study shows in our that the fate of foreign DNA in a eukaryote depends on its GC content. It can either packaged into….
science.org
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and...
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RT @RobertIllingwo7: Shifting the pitch and contours of Waddington’s valleys, putative enhancers, and transcription through H3K27me3 chroma….
journals.plos.org
Author summary Embryogenesis requires a tightly coordinated programme of cellular expansion and specialisation to gives rise to all of the cell- and tissue-types of the developing organism. In...
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RT @PawelMikulski: Happy to contribute to this excellent story about heterochromatin role in centromere maintenance, led by @ben_carty93 !….
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RT @PhysGenCenter: CPGE's most recent publication on cohesin function and chromatin domain organization is out now in Science Advances. Th….
science.org
RAD21 contributes to nascent packing domain formation, but maturation requires nucleosome posttranslational modifications.
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RT @josh_brickman: Transcription ahead of chromatin regulation? .Activation in endoderm occurs prior to K27me3 removal, plus much more. A….
journals.plos.org
Author summary Embryogenesis requires a tightly coordinated programme of cellular expansion and specialisation to gives rise to all of the cell- and tissue-types of the developing organism. In...
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RT @hyejung_won: 1/ I am beyond thrilled to share our new paper in @CellCellPress! We explored the regulatory principles underlying pleiotr….
cell.com
High-throughput experimental validation of genetic variants linked to eight psychiatric disorders reveals the regulatory mechanisms underlying variants with pleiotropic and disorder-specific effects.
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RT @mikhailspivakov: Our new paper is finally out, showing that the same enhancer sequences - and likely the same transcription factors rec….
nature.com
Nature Communications - Here, the authors study the effects of expression quantitative trait loci on enhancer activity and promoter contacts in primary monocytes isolated from male individuals,...
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