Giunta Lab
@GiuntaLab
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Giunta Lab of Genome Evolution @ University of Rome Sapienza. We study human centromeres' tug-of-war between fast evolution & essential function. AIRC funded.
University of Rome Sapienza
Joined December 2020
We have some BIG news! @Simona_Giunta has been awarded an ERC STARTING GRANT from the @ERC_Research for her project "CentroFUN". Full news here: We are incredibly happy, grateful & ready to celebrate @SapienzaRoma today - all welcome! 🍾🥂🧬.#ERCStG #ERC.
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RT @ben_carty93: What is the molecular basis for maintaining centromere size and position? In a great collaboration with @NAltemose @Giunta….
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RT @NHGRI_Director: I am starting a new video series called WAY COOL GENOMICS! Join me as I showcase examples where genomics is used in a s….
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RT @SPJacksonGroup: Two exciting opportunities for suitably qualified postgraduates/postdocs to join the Steve Jackson lab at the world ren….
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RT @Simona_Giunta: ERC-funded positions now open❗️❕❗️.Join the @GiuntaLab to understand human DNA evolution through the study of satellite….
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RT @GenomeIINetwork: Dear community, we are very happy to announce the next Giin webinar!! Don't miss it on Tuesday, April 9th, from 5PM R….
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With >100 people connected for an outstanding January session, so happy to see the GiiN #GenomeIntegrityItalianNetwork growing strong! Join us *today* with 2 exceptional speakers @DiffleyLab & @DubranaLab + check out our forthcoming 2024 series🧬.@GenomeIINetwork .@Simona_Giunta
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Thanks @Frances87274236 Here are 10 more awesome women in STEM:.@LabBallarino @yamashitaflylab @LugerLab @promiselcooper @khmiga @GrammaticoPaola @MaikoKitaoka @PasqualGiulia @neuroluci @TeresaDavoli3 pick it up and keep it moving!.
Thanks @Ivarssonlab . Here are 10 more awesome women in STEM: @NatalieKrahmer @maria_tanzer @GiuntaLab @signor_database @ChiaraFrancavi2 @charo_robles1 @chiara_dimalta @FrancesCryoEM @FrancescaNazio @CianfVale pick it up and keep it moving!.
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RT @notdatkndofdctr: We have been needing this for a long time now. Thank you and congratulations @Simona_Giunta and team.
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RT @bxv_genomics: The complete human diploid reference genome of RPE-1 identifies the phased epigenetic landscapes from multi-omics data ht….
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LINK: For early access to the complete RPE-1 assembly and any other enquiry, please contact us:
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RT @Chromosoma_EB: Chromosoma welcomes our newest Editor @Simona_Giunta at Uni-Rome/Sapienza. Simona brings deep ce….
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What have we been doing since starting the lab in 2021? Assembling human genomes & studying their centromeres at basepair resolution. A new era of epigenomic is here! Check out our first work on preprint, constructive feedback wlecome 🧬🧫❣️NB.This work is supported by @AIRC_it.
🧬Complete Human Diploid Genome Alert❗️.So proud to share our first work as @GiuntaLab now on bioRvix - a monumental feat for a single lab assembling T2T RPE1 as a new reference to achieve epigenetic precision:.It's not just the length but how you use it!😊
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We brought together our data with those from too many labs to tag, and we propose the LAYERED LOOPING MODEL of #centromere #DNA organization to favor CENP-A positioning toward the kinetochore-microtubule binding interface. We are excited to showcase this & welcome feedback!🧵4/4
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We found that the ring-like organization of alpha-satellite DNA at the mitotic centromere is present also under tension, even past metaphase. Pavan in @HironoriFunabi1 Lab showed CENP-A follows a similar organization by #ExM �3/4.
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PhD Student Elena Di Tommaso recapitulated @Simona_Giunta earlier data in two SIM platforms, OMX and Elyra @IIT showing that CenCOFISH ( is an optimal method for #superresolution imaging of DNA avoiding effects of high temperature denaturation 🧵2/4
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2015: @Simona_Giunta first imaged human centromere DNA after CenCOFISH in @HironoriFunabi1 Lab @RockefellerUni .2018-21: Presented at conferences the peculiar centromere ring structures.2021-23: Elena in the @GiuntaLab finally made the project blossom �1/4.
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RT @TeresaDavoli3: Excited to share our recent work on KaryoCreate, a new method to engineer chromosome-specific gains and losses in human….
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RT @Simona_Giunta: #DIYaneuploidy? Now it's possible! Find out how in this seminal work from dear friend & long-term scientific buddy @Tere….
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RT @GabrielMariya: 💡We are proud to empower young #researchers to follow their curiosity. That’s why we support them with ERC Starting Gran….
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