
Ben Carty
@ben_carty93
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Postdoc at the Jansen lab, @uniofoxford | @Wellcome Early Career Fellow | Junior Research Fellow, Corpus Christi College | Centromere biologist | ๐ฎ๐ช๐ป๐๏ธโโ๏ธ
Oxford, England
Joined January 2021
What is the molecular basis for maintaining centromere size and position? In a great collaboration with @NAltemose @GiuntaLab and @FachinettiLab labs, we investigate the long standing question of how heterochromatin maintains centromere size/position! https://t.co/I41gYDcL8B
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๐ Excited to share my first paper as 2nd author! From the Barr & Gruneberg labs, this work explores the structure of the Chromosome Passenger Complex (CPC) and suggests a โpivotโtetherโ model for how it binds H3pT3-phosphorylated nucleosomes (1/2) @BiochemOxford @Dunn_School
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Happy to share our latest work on the structure and assembly of holocentric kinetochores! Huge thanks to Ines for a very fruitful collaboration, Claudio for all the support, and congratulations to Christine and all co-authors! https://t.co/PP5oUXVdvW
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๐จ Hot off the press!!! Wanted to share this to celebrate the momentous achievement from the @GiuntaLab and for the human centromere / genomics communities as a whole... more posts to come next week but for now, happy Fourth & happy reading โค๏ธ๐งฌ๐ป
science.org
Centromeres are epigenetically specified by distinct chromatin, whereas their DNA varies between species and individuals. This extensive sequence divergence makes comparative analyses between...
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A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @plantsci
https://t.co/mW072iZPGz
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My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT! For more information see here: https://t.co/vHA6sDoEMm
https://t.co/6gxsBDkYFh
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Iโm excited to share the first manuscript out of my PhD work with @NAltemose, in which we describe FiberFold: a deep learning tool that predicts cell-type-specific and haplotype-specific 3D genome organization from a single experiment! https://t.co/FwJldYnCGe 1/
biorxiv.org
The three-dimensional (3D) architecture of the genome plays a crucial role in gene regulation and various human diseases. Short-read sequencing methods for measuring 3D genome organization are...
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We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today! Join us at @tcddublin on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters! Free registration: https://t.co/pTyAyps6yb
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๐ Our #ResearchIsBeautiful campaign continues to inspire! Congratulations to Danny Gold from the University of Oxford for his stunning image which captures microtubules attaching to chromosomes via kinetochores to form mitotic spindles. Hear more from
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Our post is now live! Apply and join us! https://t.co/IVjSuawnmW
I donโt post here much anymore, but this one is an important announcement for us: ๐จWe are Recruiting! So come join us! ๐จ#RNA #CancerResearch
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Biology papers be like "The nucleus is part of the cell and contains a lot of DNA. Polycomb Repressive Complex 2 (PRC2)-mediated deposition of H3K27me3 establishes domains of facultative heterochromatin, silencing gene expression in a developmentally regulated manner."
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Very excited to share our work @MahlkeMegan in great collaboration with @NAltemose @khmiga Peter Campbell and Rachel O'Neill revealing that human centromeres are heterogenous and naturally evolve over prolonged proliferation. Check it out here https://t.co/63TVGStzds
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Happy to contribute to this excellent story about heterochromatin role in centromere maintenance, led by @ben_carty93 ! Heterochrom. boundaries control centromere expansion, drift & number! Great usage of induced neocentromere model and modern epigenomics across the labs๐ฅณ
What is the molecular basis for maintaining centromere size and position? In a great collaboration with @NAltemose @GiuntaLab and @FachinettiLab labs, we investigate the long standing question of how heterochromatin maintains centromere size/position! https://t.co/I41gYDcL8B
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Fancy a postdoc on human centromere formation/inheritance in Oxford? Get those applications in! If anyone has questions about what a postdoc in the lab/Oxford is like, just drop me a message!
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Our paper discovering a centromere-localized retroelement RNA is now out in @GenomeBiology ๐! Transcription of this retroelement is higher in CENP-A chromatin where insertions of this element seem to occur preferentially. Pls check it out and RT!
genomebiology.biomedcentral.com
Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements...
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I'm a PhD student at @UniofOxford and I think I'm living in a fairytale :-) Foxes playing around in the snow at Magdalen College this morning โ absolutely magical!
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Iโm excited to share the first preprint out of the Altemose Lab! This stems from a heroic effort by Dr. Matt Franklin @matt_franklin_ (who's on the job market!), who made surprising discoveries regarding some of the most mysterious regions of the genome.
biorxiv.org
Eukaryotic genomes are frequently littered with large arrays of tandem repeats, called satellite DNA, which underlie the constitutive heterochromatin often found around centromeric regions. While...
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Repeat after me: LAB WEBSITES MATTER! While it may seem like a nice-to-have... in today's world, it's a need-to-have. For you, your trainees, and your prospective team members. I couldn't have written this better myself: https://t.co/f92599V9p3
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HRB Summer Student Scholarships are now open to support undergraduate students complete short research projects during the summer. The purpose of the scholarship scheme isโฏto encourage research interest. Learn more here: https://t.co/Wyn7VQqDKa
#ResearchOpportunity
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Want to do a DPhil @BiochemOxford ? Here is a link ( https://t.co/91DzUxEkId) to programmes that admit students. Great labs to choose from. Have a look at https://t.co/xRFjpV4GRP if you want to know more what we do in my group! Please RT!
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