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Teif Lab

@TeifLab

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Teif lab at @uni_of_essex. We work on nucleosomes, chromatin, TFbinding, CTCF, cfDNA. Find us at 🐘 and 🦋. [email protected]; [email protected]

University of Essex, UK
Joined March 2019
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@TeifLab
Teif Lab
1 year
My first interview in a major podcast :) Quite an interesting experience! Thank you very much for inviting @epigenetics_pod.
@epigenetics_pod
Epigenetics Podcast
1 year
In this episode we talked to @TeifLab from the University of Essex about his work on nucleosome positioning in #cancer #diagnsotics. #podcast #Epigenetics . Listen here:
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@TeifLab
Teif Lab
2 months
Very happy to contribute to this CTCF-nucleosome paper by @ElenaPugachev12 &Co. Exciting science and a cool journal cover!.
@ElenaPugachev12
Elena Pugacheva
2 months
Excited to share our latest study published in Nucleic Acids Research: It’s the cover story for Issue #12! We drew inspiration from Greek mythology to illustrate CTCF’s constant struggle in shaping the 3D genome architecture.
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@grok
Grok
18 days
Join millions who have switched to Grok.
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@TeifLab
Teif Lab
2 months
RT @ElenaPugachev12: Excited to share our latest study published in Nucleic Acids Research: It’s the cover story fo….
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@TeifLab
Teif Lab
3 months
NHS announced that it will start offering first liquid biopsy tests for diagnostics of lung and breast cancer; also planning expansion to pancreatic and gallbladder cancers
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@TeifLab
Teif Lab
5 months
We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and more Apply by 21st April 2025!.
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@TeifLab
Teif Lab
6 months
Very happy to contribute to this paper about cfDNA in SCLC, led by the team of Anish Thomas. It's already online in Genome Medicine:. Takahashi et al., Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor
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genomemedicine.biomedcentral.com
Background Profiling circulating cell-free DNA (cfDNA) has become a fundamental practice in cancer medicine, but the effectiveness of cfDNA at elucidating tumor-derived molecular features has not...
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@TeifLab
Teif Lab
6 months
RT @PancreaticCanUK: Early detection of #PancreaticCancer saves lives. @TeifLab @EssexLifeSci are using cutting-edge technology to measur….
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@TeifLab
Teif Lab
6 months
RT @isabella_ciu: 2nd time at #FOG2025 (1st time presenting!), it never disappoints!✨. Great talks, groundbreaking research and good times….
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@TeifLab
Teif Lab
8 months
RT @isabella_ciu: So excited for the festival and this great opportunity to present my research 😄.
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@TeifLab
Teif Lab
8 months
RT @isabella_ciu: Low quality picture but….Had to show the matching glasses 🤭🤓
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@TeifLab
Teif Lab
8 months
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@TeifLab
Teif Lab
8 months
Interestingly, the BBC coverage attributed this success to NHS testing vans stationed in busy areas where any person can walk-in without referral. Probably technological genomics developments also contributed to this improvement, in any case these are set to help going forward.
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@TeifLab
Teif Lab
8 months
Encouraging news to start the new year: NHS reports 2.7% improvement in early cancer diagnostics in comparison to pre-pandemic levels. An estimated additional 7,000 patients diagnosed at an early stage.
@NHSEngland
NHS England
8 months
Latest NHS data shows that the proportion of patients being diagnosed with cancer at an early stage in England has risen to its highest ever level. Find out more about the latest data. ➡️
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@TeifLab
Teif Lab
8 months
Happy New Year! 2024 was not easy, but despite many challenges we also achieved a lot. We've got grants, published papers, have new exciting findings. This would not be possible without support of friends and collaborators. Wishing you health, happiness, peace & success in 2025!
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@TeifLab
Teif Lab
9 months
Thank you very much @PancreaticCanUK for supporting our research! In collaboration with Andrea Mohr, Ralf Zwacka and Greg Brooke, we are developing a new generation of liquid biopsies for early cancer detection based on the analysis of cell-free DNA 🧬.
@PancreaticCanUK
Pancreatic Cancer UK
9 months
Today we are thrilled to announce that we're investing almost £1 million into two new research awards which aim to improve the early detection of #PancreaticCancer 🔬
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@TeifLab
Teif Lab
10 months
Interesting preprint on nucleosome spacing from cfDNA [Johnston et al., 2024] The authors refer to NRL changes 10n -> 10n-5 bp. Earlier we showed that NRL decrease in cancer is more complex & context-specific [Jacob et al., 2024]
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@TeifLab
Teif Lab
10 months
Hope to see some of you in Hong Kong next year! Circulating Nucleic Acids in Plasma and Serum, 14th CNAPS International Symposium. Hong Kong, December 3-5, 2025. #SNAPS2025 #cfDNA #liquidbiopsy
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@TeifLab
Teif Lab
10 months
RT @generegulation: some statistics about mass migration of scientists, specifically for our field: .▶️~30% of our followers created accoun….
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@TeifLab
Teif Lab
10 months
Dear friends, please reply if you know a neurosurgeon in Romania (or close contacts among medical doctors in Romania who may connect with neurosurgeons). This is for a medical emergency, not for academic research.
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@TeifLab
Teif Lab
10 months
RT @MGO_BPS: 📢 The 2025 Biophysical Society Annual Meeting in LA is around the corner, and we need nominations/self-nominations for 5 leade….
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@TeifLab
Teif Lab
11 months
This idea is very interesting, but did anyone try to check such hypotheses (re: HP1a) with nucleosome maps? More generally, looking for publications where NRL changes are shown for local regions enriched with certain proteins (excluding studies regarding gene bodies & TF binding).
@generegulation
Gene Regulation
11 months
Heterochromatin protein 1 alpha (HP1α) undergoes a monomer to dimer transition that opens and compacts live cell genome architecture ▶️Monomeric HP1a increases nucleosome spacing.▶️Dimeric HP1a decreases nucleosome spacing.▶️Conclusions based on FLIM-FRET
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