David Ting
@davetingmgh
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Physician scientist, cancer biologist, bioengineer, and dad trying to cure cancer.
Joined February 2022
LINE-1 ORF1p Mimics Viral Innate Immune Evasion Mechanisms in Pancreatic Ductal Adenocarcinoma
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The final #DarkGenomeSymposium panel discussion will discuss: “Are Dark Antigens the Key to Off-The-Shelf Approaches for Next-Generation Immuno-Oncology Targets?” #DGS2024
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Up next at #DGS2024 is a panel discussion entitled “Beyond Coding: Unraveling the Regulation and Unconventional Functions of the #DarkGenome” featuring panelists from both industry and academia.
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⭐️NEW PAPER OUT in @Nature⭐️ 🫀What is the relationship between the immune responses in the heart, blood, and tumor in patients with inflammation in the heart resulting from cancer immunotherapy (irMyocarditis)? This 🧵 breaks down the key findings 1/n https://t.co/0Jdhrw63VX
nature.com
Nature - The molecular characteristics of myocarditis associated with immune checkpoint inhibitors are described and potential biomarkers of onset and severity are identified.
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Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms https://t.co/Mh2OgEohck
@immunitycp @bengrbm @sunsiyu1
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The next #DGS2024 panel will discuss the question: “Is the #DarkGenome an instigator or innocent bystander in autoimmunity and neurodegeneration?” Looking forward to further illumination of this next frontier in biology and its potential role in challenging diseases.
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We’re proud to debut the first preclinical data of ROME’s LINE-1 RT inhibitors in #NeurodegenerativeDiseases at #DGS2024. These data in #ParkinsonsDisease will be presented at a short talk podium presentation later this morning. Learn more: https://t.co/GQgzWJWnTe
#DarkGenome
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Really exciting work in illuminating the Dark Genome in pancreatic cancer immunity. Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms: Immunity
cell.com
Overexpression of transposable elements is a common feature of cancer. Sun, You, et al. show that, in pancreatic ductal adenocarcinoma, tumor cells adapt through different mechanisms to mitigate a...
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Excited to share our work on “Identification of Pancreatic Cancer Germline Risk Variants With Effects That Are Modified by Smoking”, published today in JCO Precision Oncology @JCOPO_ASCO
ascopubs.org
PURPOSEPancreatic cancer (PC) is a deadly disease most often diagnosed in late stages. Identification of high-risk subjects could both contribute to preventative measures and help diagnose the...
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In the latest issue! Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy
cell.com
Transfer of mitochondria via nanotubes from bone marrow stem cells to CD8+ T cells augments cellular metabolism, empowering engineered T cells and tumor-infiltrating lymphocytes to counteract...
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Quite surprised to receive this and honored to have been nominated by my colleagues - together we are trying to change how we do collaborative research and ultimately, how we treat #AML. David Livingston was a legend here @DanaFarber and in the cancer research community.
We are proud to recognize Dr. Andrew A. Lane of @DanaFarber with the David M. Livingston Collaboration Award. This award recognizes those who exemplify the commitment to collaboration and sense of urgency that David, an inspirational cancer researcher and driving force behind
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And I should add that we are affiliated with the @DanaFarber soon
A combination of high case complexity and volume with a burgeoning transplant center, not to mention the amazing faculty and collegial atmosphere. If you are a GIPath enthusiast, look no further for further training and career advancement! @BIDMCpath
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In the latest issue! Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues
cell.com
Patho-DBiT enables spatial profiling of a range of RNA species (i.e., mRNA, microRNA, tRNA, splicing isoform, etc.) all at once in clinical formalin-fixed paraffin-embedded tissue with high sensiti...
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The cancer risk of repeat RNAs | Science Signaling
science.org
Repeat RNAs reprogram tumor cells and cancer-associated fibroblasts in pancreatic cancer.
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We are hiring a Software Engineer for the new Olayan Center for Cancer Vaccines @MSKCancerCenter. We hope you will consider joining our new endeavor with @TheVinodLab! Experience in development for varied users, Comp Bio & AI/ML is a plus 👇👇👇 https://t.co/QUdjdZmjic
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Our CSO Heike Keilhack is speaking on the “Innovation without Borders: How the Immigrant Mindset has Helped Power the Biotech Industry in the U.S.” panel on the intersection of immigration, innovation, and biotechnology. Register here: https://t.co/6dVFyGyZ26
@LabCentral
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💇♂️ I might be biased, but I’m pretty sure I have the best hair in the game. 💁♂️✨ #HairGoals #Flawless
Issues around macroscopic examination of GI specimens will be discussed by internationally renowned experts from USA, UK and India in this free webinar on 16th October 2024. Register at https://t.co/TmFc4BvrPi.
@DiptiKaramchan2 @Mvgs1706 @Vik_deshpandeMD @RunjanChetty
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Now online! Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer: Cell
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Congratulations @davetingmgh @EunaeYou476 on their latest work in @CellCellPress, showing how repeat RNA elements in extracellular vesicles create a viral-like infection in the pancreatic cancer microenvironment.
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