Daniel Bojar
@daniel_bojar
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#ML, Glycans, & #SynBio | Associate Professor @wcmtm_ugot @goteborgsuni | Forbes 30 Under 30 Europe | Branco Weiss Fellow | Foresight Fellow
Gothenburg, Sweden
Joined April 2017
After 2.5 years of development, glycowork releases its version 1.0 ๐ฅณ๐ ๐it, use it, add to it. Countless small improvements in this update, but I want to talk about two *big* changes: universal input & native, narrow wildcards ๐ฅ #glycotime
https://t.co/ViE100aueC
github.com
Package for processing and analyzing glycans and their role in biology. - BojarLab/glycowork
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Here's something non-science-y for a change: Check out the free demo of my upcoming game on Steam! ๐ฅณ (Arcaneering is a cozy factory automation game, with a bit of RPG elements, made in Godot) #gamedev #indie #pcgaming #automation #basebuilding
https://t.co/Uyy63b0t0e
store.steampowered.com
Automate the arcane! Build spell-powered factories, reclaim ancient territories filled with magical secrets, and discover game-changing technology hidden across procedurally generated worlds. Master...
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Warm congratulations to new LS1 @ERC_Research grantees ๐ฅณ๐ฅณTom DENDOOVEN (@structbiolbxl), @MartinPacesa, @MMSchuhmacher, @LFMilles, @preinerin, @MarkusHopfler, @CharleneBoumen1, @AffProf, @ShifraLansky, @alexanderbelyy1, Erik Benson (@scilifelab), @daniel_bojar! #ERCStG
๐ฃ The ERC Starting Grant call results are out! Find out which early-career researchers will receive funding, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025! โก๏ฟฝ๏ฟฝ๏ฟฝ https://t.co/cGctMhcJos ๐ช๐บ #HorizonEurope
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Remember The Glycans: Consideration of Glycans in Evaluating the Threat of Mirror-Image Life Forms https://t.co/d3fE2tthux by 32 #glycobiology PIs @ChemicalBiology @CarolynBertozzi @GlyCosmos @peterseeberger @daniel_bojar @FeiziTen @Lowarylab @sjwill99 et al #RememberTheGlycans
science.org
Broad discussion is needed to chart a path forward
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Glycomics is quite different from other omics and sometimes requires a bit different approach to data analysis. Excellent paper by @daniel_bojar and @mtandersen_lab just got published in @NatureComms
nature.com
Nature Communications - Bennett et al. develop a statistical approach for analyzing comparative glycomics data that accounts for inherent data dependencies, yielding robust and sensitive results....
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glycowork v1.4 is live! ๐ฅณ๐ข๐ฆ๐ฆ Development always continues but we want this to be maximally useful for the entire glyco-community, so let us know if you have a feedback (or if you want to contribute:-) ) #glycotime
https://t.co/sLIrmnzgnQ
github.com
Change Log For Version 1.4.0 Added an example workflow/tutorial for differential glycomics analysis to the Examples tab in the documentation Added additional tests via pytest Cleaned up repo with ...
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I returned to the molecules of my master's thesis: Glycans In #GIFFLAR, I use Combinatorial Complexes and Higher-Order Message Passing to extract every bit of information from #glycans into a #GNN Check out my work together with @daniel_bojar
https://t.co/I7BM62fVLW
#glycotime
arxiv.org
Glycans are the most complex biological sequence, with monosaccharides forming extended, non-linear sequences. As post-translational modifications, they modulate protein structure, function, and...
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Watch out for our new sticker at upcoming conferences:D Gotta get onto all of your laptops (or phones, I don't judge) #glycotime
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Traveling back from the #GlycoTwinning summer school in Lisbon; lots of exciting #glycotime & great to see so many interested researchers:-) And we found monosaccharides in downtown Lisbon!! ๐ฆ๐จ๐บ๐ข๐ต
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#BreastFeedingAwarenessMonth
@Locke_Marissa covers @daniel_bojar et al.'s study about how components of breast milk from mammals possess immunomodulatory components that may promote healthy microbiome colonization in offspring. https://t.co/XjpoUSvblb
@USbreastfeeding @molcellprot
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Explainable diagnostic fragments for O-glycans! A huge+diverse dataset, a bit of machine learning, and you get potent/exhaustive/generalizable rules that analysts can follow to annotate isomers & attach quantitative confidence scores to their annotation:-) https://t.co/JcFPEC2DqZ
biorxiv.org
Structural details of oligosaccharides, or glycans, often carry biological relevance, which is why they are typically elucidated using tandem mass spectrometry. Common approaches to distinguish...
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A new #AI model named "CandyCrunch" revs up the field of glycomics with such applications as rapid cancer detection https://t.co/pCqNXpAAuo
@naturemethods
nature.com
Nature Methods - CandyCrunch is a deep learning-based tool for predicting glycan structures from tandem mass spectrometry data. The paper also introduces CandyCrumbs that automatically annotates...
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Meet CandyCrunch, our AI-glycomics model featured in @naturemethods! Trained on 500k spectra for rapid glycomics analysis on all glycan types. @ElisaTelisa, @CallumMIves, @karlsson_niclas, @_jurban More data=better models, so keep on uploading! #glycotime
https://t.co/2BnoGEZW65
nature.com
Nature Methods - CandyCrunch is a deep learning-based tool for predicting glycan structures from tandem mass spectrometry data. The paper also introduces CandyCrumbs that automatically annotates...
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๐๐๐ข๐๐ง๐ญ๐ข๐๐ข๐ ๐๐๐ญ๐ฐ๐จ๐ซ๐ค ๐๐๐๐ญ๐ข๐ง๐ & ๐๐ฎ๐ฆ๐ฆ๐๐ซ ๐๐๐ก๐จ๐จ๐ฅ 3-6 Sept 24 Check the detailed programme at the dedicated webpage of our website in https://t.co/eMHgouYT16 , where you canย express your interest by 30/06. #glycoscience #glycotime #summerschool
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Featuring one of my favorite stories on work by @daniel_bojar on #breastmilk sugars from diverse animals like rhinos, dolphins and whales! #biochemistry #molecularbiology #glycobiology #glycan
https://t.co/vDAK4yAWqz
asbmb.org
In study of diverse mammalsโ breastmilk, researchers find shared immunomodulatory components.
Have you checked out our new science categories on #ASBMBToday? Now you can browse stories about cutting-edge research by topic. Here's a staff member's fave: "Animals & other creatures." Read on for articles about snake venom, water bears, corals & more: https://t.co/JxeA3oOSF7.
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Compositional data analysis for comparative glycomics! Learn why you can't live without it:-)#glycotime glycowork v1.3 tackles glycan abundance interdependence +uncertain absolute amounts via CLR/ALR transformations&scale models, yielding reliable findings https://t.co/0IlTEJoXA3
biorxiv.org
Comparative glycomics data are an instance of compositional data defined by the Aitchison simplex, where measured glycans are parts of a whole, indicated by relative abundances, which are then...
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"A random half of panelists were shown a CV and only a one-paragraph summary of the proposed research, while the other half were shown a CV and a full proposal. We find that withholding proposal texts from panelists did not detectibly impact rankings." https://t.co/IVXjvGqUDI
link.springer.com
Scientometrics - Scientists and funding agencies invest considerable resources in writing and evaluating grant proposals. But do grant proposal texts noticeably change panel decisions in single...
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Probably won't reach the right people here but I have seen *so* many papers using our original 2020 glycan-taxonomy 13k dataset for building stuff; for the love of god, *please* use the 37k dataset from glycowork ๐ตโ๐ซIt's not only bigger but also much cleaner
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glycowork GUI gets a boost in v1.3 too; smaller filesize, more documentation, more functions that are exposed in the graphical user interface! #glycotime
Nay to simple up/down, aye to diversity & distribution shifts. Bring alpha- and beta-diversity analyses to glycomics data with v1.3 ๐(both multi-group and motifs are supported of course) #glycotime
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Nay to simple up/down, aye to diversity & distribution shifts. Bring alpha- and beta-diversity analyses to glycomics data with v1.3 ๐(both multi-group and motifs are supported of course) #glycotime
The upcoming v1.3 will also allow you to find the best glycan biomarkers with the new get_roc function (motifsโ
multiple groupsโ
<censored>โ
) #glycotime
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