Just look at how the rate of increase in life expectancy has been dropping in this country. And it’s not just since COVID/2020. The decline seemed to start around 2010… weird, that.

🚨New analysis from @royalsociety UK visa costs for researchers: 🫣 21x higher than France (Talent passport for researchers) 😱34x higher than Germany (Scientific visa) 😬Have increased by 126% since 2019 while other countries have made theirs cheaper https://t.co/WAr312t6Zd

You know those times when you come out of a theater and just know that film would win Best Picture…this is the human genetics equivalent. I’m not prone to hyperbole but cannot remember the last time I was this impressed by a genetics manuscript. Congratulations!

Congratulations to @bmss_official , @PerditaB and everyone involved in making this possible! A much needed investment into UK's mass spectrometry infrastructure. Thank you, @The_MRC @UKRI_News !

Congrats - an incredible resource!

A BBSRC-funded PhD position is available to investigate how plants shape stress memories. With Mark Collins and @Katherine_Denby. Please RT and spread the news! For further details, check FindAPhD: https://t.co/jLE7WEmxE5

Phosphorylation based signalling is still quite understudied despite a general perception that it is well understood. A great study here measuring specificity for human serine/threonine kinases https://t.co/FuLA2kymTh

So sad to hear the news of the passing of my mnd hero Doddie Weir. I'm sorry to say, how many more warriors die before this stupid government give the 50m they said they would give. I'm absolutely gutted to see my friendly giraffe die. You are the reason for being so positive RIP

We have several new lectureships available! Sheffield is a great place to live, work and do science. If you or anyone you know want to join us, please get in touch! Please retweet.

Great work Mohamed!

Dear @BorisJohnson, I hear Rwanda is a lovely place to spend your retirement. Ken

Our paper on sgRNA profiling of #SARSCov2 @nanopore @NetworkArtic genomes using periscope showing lineage specific changes is finally out! We find a striking increase in sgRNA abundance in B.1.1.7 infections and a potential sgRNA for ORF9b! 💥 https://t.co/Hb1EsEB543 short 🧵1/3

#JBCMethodsMadness Championship is tomorrow at 12:00 p.m. ET! #TeamMassSpec vs. #TeamCryo 🟦🟨Be there or be square🟨🟦

#OpenCell – Proteome-scale measurements of human protein interactions and localization is now published in @ScienceMagazine. In collaboration with the @czbiohub we leverage #CRISPR technology and combine ultra-sensitive #proteomics with confocal imaging. https://t.co/l2m6j5vAKo

new out in Nature:

I would like to thank many friends and colleagues for messages of support on the first day of Russian invasion of #Ukraine! For those, who would like to contribute to the humanitarian effort, please consider donating to @BritishRedCross:

DHHC enzymes catalyze protein palmitoylation in thousands of substrates. We used a combination of crystallography, computational simulations and biochemistry to present the first structure of a precatalytic complex of human DHHC20 with palmitoyl CoA. https://t.co/pkEwS2LfFH

Proteomics + neurobiology are powerful combo! Here we describe a multimodal (APEX, APMS) and dynamic (stimulation, mutants) PPI analysis for tau that enhances our understanding of both tau molecular biology as well as clinical protein profiles from AD patients.

“Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants” by Eunju Shin et al. Nature Communications https://t.co/wY3dsYmESM