Journal of Biological Chemistry
            
            @jbiolchem
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              The Journal of Biological Chemistry is a publication of @ASBMB. Publishing research motivated by biology, enabled by chemistry.
              
              Rockville, Md.
            
            
              
              Joined March 2012
            
            
           🚀 #AuthorInterview | Dr. Uzma Salim @UzmaSalim4, PhD from Prof. Vivekanandan Perumal’s lab at @iitdelhi, discusses her work “The G Factor: RNA G-Quadruplexes Drive Mammalian Mirtron Biogenesis” published in @jbiolchem. Read more 👉  https://t.co/M6HJKqgWFx 
            #RNA #ResearchSpotlight
          
          
                
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            @SanhitaRoy12 @jbiolchem @RIDDHIA79109299 @akshita1699 @Srijita__Kundu Congratulations Sanhita!!! This is such a cool picture!
          
          
                
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             We just shipped the first VS Code extension built specifically for @Solana developers. Static analysis detectors that catch vulnerabilities in the IDE + fuzzing coverage visualization. The missing layer between development and audits, integrated into devs' workflow ↓ 
          
                
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             Spend #Halloween with zombie proteins! Originally thought to be dead evolutionary remnants, #pseudokinases have since been revealed to play remarkably diverse noncatalytic roles in biological pathways. 🧟‍♂️ Learn more in this #JBiolChem review:  https://t.co/o3Qy6oqKNt. 
          
          
                
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             New in JBC press: "Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding." Learn more:  https://t.co/CpCgYOnkNH 
            #jbiolchem
          
          
                
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             New in JBC press: "Scientists explored the transcriptional responses of islets to endogenously produced cytokines following immune stimulation with the bacterial pathogen-associated molecular pattern lipopolysaccharide." Learn more:  https://t.co/FpV6LHYZJt 
            #jbiolchem
          
          
                
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             Our most recent work has been published in JBC @jbiolchem Congrats to the team!  https://t.co/X80S1si4FF 
          
          
            
            jbc.org
              Inhibition of purinergic signaling in cancer has recently received great attention. The purinergic ecto-enzyme CD73 represents a prominent candidate, however its intrinsic role in colorectal cancer...
            
                
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             Following our previous reports on battle b/w #Leishmania & #Nramp1 for #iron,now @jbiolchem mechanisms from @rupak_iiserk lab-how #Leishmania GP63 alters #macrophage hepcidin. Exciting  https://t.co/BtjdlP3nhT.🎉suman,  it was special to work on this project during my PhD @iiserkol
          
          
            
            jbc.org
              Micronutrient sequestration is a powerful host defense mechanism against intracellular pathogens. A key player in this is Nramp1, which effluxes iron from phagolysosomes thereby depriving the...
            
                
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             Editors' Picks| Neurodevelopmental disorder mutations in the exchange factor DENN/MADD disrupt activation of Rab GTPases Learn more:  https://t.co/MudNQCImwt 
            #jbiolchem
          
          
                
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             Tight Ends love a challenge! So be like @pat_fry5 & catch a great deal. Accept and complete the National Tight Ends Day Challenge at @littlecaesars & score free Crazy Puffs®. 
          
                
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             Inside @JbiolChem: New research sheds light on the fundamental mechanism of gene regulation by the Mediator complex. ➡️Read "N-terminal half of MED14 is critical for Mediator-RNA polymerase II interaction and the resulting transcription" here:  https://t.co/gq2bOKKtcl. 
          
          
                
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             New in JBC press: "Pathogenic variants in KCTD1 disrupt cAMP signaling and cellular communication associated with developmental pathways." Learn more:  https://t.co/J94H0yd3Zf 
            #jbiolchem
          
          
                
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             It’s #WorldCRISPRday! To celebrate, revisit this @jbiolchem review:  https://t.co/jezoqEBCat.  Tina Liu & Jennifer Doudna explore how Class 1 CRISPR-Cas systems are expanding possibilities for DNA/RNA editing, gene expression control & nucleic acid detection. 
          
                
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             Delve into the importance of evaluating cyanobacterial physiology based on different biomass quantitative units to avoid misinterpretation of results in this JBC paper, a case study of PsbU in Synechocystis sp. PCC 6803 using CRISPRi:  https://t.co/1bO663FEKO. 
            #WorldCRISPRday
          
          
            
            jbc.org
              Photosystem II (PSII) is a multiprotein complex and plays a central role in oxygenic photosynthesis. PsbU, a 12 kDa subunit of PSII, is associated with thermotolerance and structural stabilization of...
            
                
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             Inside @jbiolchem | Researchers at Drexel University uncover how the vancomycin-resistant bacterial sensor binds to the antibiotic, offering insights to guide inhibitor design that restores antibiotic effectiveness against hospital-acquired infections.  https://t.co/xfJuXnfsuG 
          
          
            
            asbmb.org
              Researchers at Drexel University uncover how the vancomycin-resistant bacterial sensor binds to the antibiotic, offering insights to guide inhibitor design that restores antibiotic effectiveness...
            
                
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             New in JBC press: "Scientists' data illustrate how the modular nature of these chemokines enables their overlapping but non-redundant functions." Learn more:  https://t.co/k3oKDvwiTU 
            #jbiolchem
          
          
                
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             “A man who has the knowledge but lacks the power to express it is no better off than if he never had any ideas at all.” -Pericles 
          
                
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             New in JBC press: "Putative receptors and signaling pathways responsible for the biological actions of epoxyeicosatrienoic acids." Learn more:  https://t.co/mSHzs53fa9 
            #jbiolchem
          
          
                
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             JBC: On the cover! This immunofluorescence image of a mouse intestinal organoid highlights successful peptide delivery (green) targeting NHERF4 sequences that regulate GCC activity in the intestinal epithelium. ➡️More in this paper by Ramananda et al.:  https://t.co/gL4NPfWExw. 
          
          
                
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             Happy to share our work on a T6SS effector with ADP ribose cyclase activity, published in JBC @jbiolchem Great work of Julius Martinkus and (always) great collaboration with Dukas Jurenas and @LaurentTerradot
             https://t.co/zZeIuRembe 
          
          
            
            jbc.org
              Bacterial polymorphic toxins are modular weapons that mediate intermicrobial competition and host interactions by delivering diverse cytotoxic domains through specialized secretion systems. Here, we...
            
                
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             New in JBC press: "Scientists identified the heterodimeric amino acid transporter as being responsible for transporting NA-Fe(II) complexes into the vascular system." Learn more:  https://t.co/95cHLUdnKX 
          
          
                
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             We've been cooking something up in the studio. The @nvidiastudio that is, letting us create without limits. 
          
                
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             New JBC press: "findings reveal HDAC7’s role in the euchromatic H3.3 chaperone network and the impact of HDAC7 depletion on chromatin dynamics." Learn more:  https://t.co/TFg7lMS5Eq 
          
          
                
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             New in JBC press: "Cysteine redoxome landscape in the liver of male mice fed a high-fat high-sucrose diet." Learn more:  https://t.co/NZmOfcfKzE 
          
          
                
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