Molecular and Cellular Biology
@MCB_Sheffield
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Research cluster within @ScienceShef, @sheffielduni focusing on molecular and cellular processes that underpin life.
Sheffield, UK
Joined October 2021
We are @MCB_Sheffield a group of molecular and cellular biologists aiming to understand the fundamental processes that underpin life. This allows us to find out what goes wrong in disease, discover new ways for therapeutic intervention and design new biotechnologies.
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Stem cell therapy's promise threatened by genetic risks: An international workshop of scientists, regulators, and industry experts led by Prof Ivana Barbaric convened to address the risks of genetic mutations in stem cell therapy https://t.co/UhQGZAMXya
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MCB external seminar today: Dr Peter Martin from ICR London "Mitotic Genome Stability:ย The Key to Precision Cancer Therapy?" ๐ Alfred Denny Conference Room ๐
2nd April - 1pm @ScienceShef
@TUOS_Cancer
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Scientists identify key protein driving ovarian cancer spread- A new study has identified the protein ADAMTS5 as playing a crucial role in the spread of ovarian cancer cells, offering a potential new target for future treatments @ERainero_lab
https://t.co/Pu4JmkFoQI
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Prof Karuna Sampath, @uniofwarwick, is visiting us today - Alfred Denny Conference room, 1pm: "Identifying the mechanisms governing extra-embryonic yolk syncytial layer development" Hosted by @IanSudbery. @ScienceShef Sponsored by New England Biolabs
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Prof Aga Gambus (@AgaGambus ) will be our external seminar speaker today - looking forward to hear her work on 'The novel replication initiation factor, DONSON: function, structure and regulation'. 1pm, Alfred Denny Conference Room. Sponsored by @merckgroup
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A great opportunity to join us!! Deadline for application: 17th of March ๐
๐จLong term postdoc position available on the reconstitution of lipid kinases!๐จ Do you have a passion for protein reconstitution and lipid signalling? You will reconstitute lipid kinases to determine their kinetic regulation. https://t.co/C0iC2gJLDX
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๐จ Fully funded summer research opportunity! ๐จ Yorkshire uni students: Spend 9 weeks in my lab using high-resolution microscopy to visualiseย Streptococcus pneumoniae! ๐ฆ ๐ฌ ๐
Apply by March 8th ๐ https://t.co/xRksHwm9Pz
#Internship #Microscopy #Microbiology #STEM #AFM
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Today we welcome Dr Catherine Hogan @cardiffuni, who will present her work on 'Cell-cell interactions with normal epithelial neighbours determines KRAS mutant cell behaviour and fate'. 1pm - Alfred Denny Conference room @TUOS_Cancer @ScienceShef
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Thrilled to know that our own @ZheBao_Sheff has been selected to present his work at the #Biologist@100 conference @Official_BSCB!! @MCB_Sheffield @TUOS_Cancer @ScienceShef
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Today we welcome Dr Carlos Lopez Garcia, from @CRUK_MI , who will present his work on "Developing a new strategy to model lung squamous cell carcinoma using human bronchial cells" - Alfred Denny Conference Room, 1pm @TUOS_Cancer @ScienceShef
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Today we're delighted to host Dr Antonio Calabrese from the University of Leeds. He seminar will be at 1pm - Alfred Denny Lecture Theatre 1, "Illuminating the molecular choreography of intrinsically disordered proteins involved in neurodegeneration and viral replication"
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Congratulations to Dr Weiwei (Erdman lab) on passing her PhD viva!!!๐๐ @ScienceShef
@sheffielduni
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Congratulations to Dr Ahmed (Erdman Lab) on passing his PhD viva!!! ๐๐ @ScienceShef @sheffielduni
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Congratulation Mubarak (Kai Erdman's lab) on passing your PhD viva today!!!! ๐ @ScienceShef @sheffielduni
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๐ขNew publication alert! The Fat-Dachsous planar polarity pathway competes with hinge contraction to orient polarized cell behaviors during Drosophila wing morphogenesis by @struttlab
@ScienceShef @sheffielduni
https://t.co/4Q4uesRzWA
pubmed.ncbi.nlm.nih.gov
During tissue morphogenesis, an interplay of biochemical pathways and mechanical cues regulates polarized cell behaviors, the balance of which leads to tissues reaching their correct shape and...
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๐ฃ New paper alert!! Inhibition of EphA2 by syndecan-4 in wounded skin regulates clustering of fibroblasts by Mark Bass lab! @ScienceShef @sheffielduni
https://t.co/VzKcmhEpZu
pubmed.ncbi.nlm.nih.gov
Upon injury, fibroblasts in the surrounding tissue become activated, migrating into the wound in a controlled manner. Once they arrive, they contract the wound and remodel the stroma. While certain...
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๐ฃ New publication alert!! SENP3-FIS1 axis promotes mitophagy and cell survival under hypoxia, by @lab_guo @ScienceShef @sheffielduni
https://t.co/1BL4gMK7OM
nature.com
Cell Death & Disease - SENP3-FIS1 axis promotes mitophagy and cell survival under hypoxia
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Unlocking the secrets of metastasis: Cancer cells' 'eating' ability could lead to new treatments https://t.co/54N26Wh7d7 via @medical_xpress
medicalxpress.com
Cancer is one of the most formidable health challenges of our time, affecting nearly half of us during our lives. While treatments have significantly improved in recent decades, the biggest challenge...
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๐ The latest paper from out lab by @Montse_Llanses with @KeqianN, @ZheBao_Sheff, @RacheleBacchet1 & @ShengnanYuan is out!!! @PLOSBiology @MCB_Sheffield @ScienceShef @TUOS_Cancer
https://t.co/iVXoyDWNaL
journals.plos.org
This study identifies novel kinase regulators of extracellular matrix (ECM) internalization through a high-content screen, characterizing the ฮฑ2ฮฒ1 integrin/p38 signaling axis as required for the...
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