Danielle Swaney
@dlswaney
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Associate Professor at UCSF, visiting scientist at the Gladstone Institutes. Expertise in mass spectrometry and proteomics. Views are my own.
San Francisco, CA
Joined July 2015
This @mjmaccoss preprint about QC is too real. Like when your turbo pump explodes and sends shrapnel into every crevice of your mass spec causing problems for half a year. This QC platform help you know when your instrument is actually all clean again :)
biorxiv.org
A thorough evaluation of the quality, reproducibility, and variability of bottom-up proteomics data is necessary at every stage of a workflow from planning to analysis. We share real-world case...
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FYI Bay area mass spec aficionados - this symposium on mass spec in drug discovery looks great! Oct 29th @ at Stanford.
Join us for the inaugural SCI Advances in #MassSpectrometry Enabled Drug Discovery symposium on October 29. Hear leading experts explore current challenges, opportunities, & recent achievements across diverse applications in #DrugDevelopment. #proteomics
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RT @apwiita: Interested in #proteomics/related data analysis but don't know where to start❓Our 2-day hands-on workshop🙌 @UCSF is for you!….
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RT @joeBondyDenomy: Did you know that phage can inject DNA, many proteins, recruit host membrane/membrane proteins and assemble a lipid ves….
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Also, a big thanks to our generous sponsors! Come hear from them about their latest and greatest technology and how it could help to accelerate your research. @thermofisher @bruker @NautilusBio @seer_bio.
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In eRA Commons a green "Council review completed" status means a grant still has a chance for funding? I have an NIGMS grant with a fundable (but not amazing) score and it has been in this status since October. PO doesn't respond to email or call to discuss, so I am being patient.
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RT @AmandaLSmythers: On #InternationalWomensDay, I want to throw back to this article I wrote for @eLifeCommunity about my abortion during….
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Andrea is awesome to work with! 10/10 would do it again. Creative, smart, and knows how to focus and get projects done. You are in for a fun ride if you work with him.
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Random shower thought: I would love to see a few famous scientists interviewed on the Hot Ones show.
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At my US HUPO lightning talk I made a silly slide about how using SEC-MS for studying host-pathogen interactions would stop classic Reviewer #2 critiques. It worked!! @anfossati got the best 1st round reviews ever. R2 says: "Thus, the paper can be accepted in its native form." 🥂
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RT @Coon_Labs: @TheCoxLab and @Coon_Labs scientists succeeded in developing a new method to generate a more detailed #proteome than ever be….
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Thanks to all who responded to my Vanquish Neo call for help. Here is an update. TLDR: we think desalting tip C18 particles were leaking into final sample, building up on the needle seat, and retaining hydrophobic peptides. Full troubleshooting details:
#VanquishNeo users - What do I have to do to make this LC like me? We got 3 installed recently and we are seeing this problem where we progressively lose signal during the gradient. Example image from earlier this month (top) vs. today (bottom). Happening on 2 of 3 LCs.
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RT @andreafossati9: New preprint alert!. Here we show how SEC-MS is a powerful tool for host pathogen interactions profiling. We applied it….
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#VanquishNeo users - What do I have to do to make this LC like me? We got 3 installed recently and we are seeing this problem where we progressively lose signal during the gradient. Example image from earlier this month (top) vs. today (bottom). Happening on 2 of 3 LCs.
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PTA supported programs like these enrich student learning and have the potential to significantly change the trajectory of a child’s academic career, enabling greater access to college, and ultimately opening doors to careers that might otherwise have been closed.
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Likely their PTA budgets are small and largely based on donations. As a member of such a PTA, I can confidently say your money will be immensely appreciated and well used. It will support things like math and literacy support teachers, field trips to local science museums, etc.
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I firmly believe that greater equity in childhood education is a critical component to bringing greater diversity and equity to science. As you consider charitable donations this year, consider the PTA of a local public school supporting populations under-represented in science.
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Hey @SFPD- not fucking good enough. Today an unhoused person snuck into my kid’s school playground and refused to leave. School went into lockdown. It took 78 min and 2 calls to 911 before police arrived. You were so damn slow the person had thankfully already left on their own.
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