Moving away from the field’s do-it-yourself ethos and embracing professional technical expertise will make research more efficient.

By insisting that every brain-behavior association study include hundreds or even thousands of participants, we risk stifling innovation. Smaller studies are essential to test new scanning paradigms.

Larry Abbott, Terrence Sejnowski and Haim Sompolinsky split $1.45 million in recognition of their decades of work uncovering principles of brain structure and function.

Thirty years ago, theoretical and experimental neuroscientists rarely went to the same conferences. So I helped launch a meeting to get them talking.

When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.

Known for his work bringing oxytocin studies to the mainstream, Young died unexpectedly last month.

Our lab adopted practices to make data- and code-sharing feel safer, including having the coding equivalent of a dive buddy. Trainees call the buddy system a welcome safety net.

New methods make it possible to probe the neural substrates of memory with unprecedented precision. Making the most of them demands careful experimental design.

Neuroscience experiments are moving toward the analysis of more complex behaviors, enabled by increasingly sophisticated tools. But we shouldn’t abandon simpler paradigms.

Video data are enormously useful and growing rapidly, but the field lacks a searchable, shareable way to store them.

The director of the Center for Neural Science shares a ghost story and talks about his collaboration with Todd Sacktor.

Different circuits between the millimeters-wide structure and the cortex go awry in Tourette syndrome, obsessive-compulsive disorder, dystonia and Parkinson’s disease, a new study of human brain...

Abstract. The Brain Imaging Data Structure (BIDS) is a community-driven standard for the organization of data and metadata from a growing range of neuroscience modalities. This paper is meant as a...

I got answers from Bratislav Misic, who is inventing practical ways to connect the brain’s microscopic features with its macroscopic organization.

Nature Human Behaviour - The combination of general anaesthesia and neuroimaging holds unique potential for catalysing integrative and translational discovery about human brains and consciousness....

To better understand mood disorders—and to develop more effective treatments—should we target the brain, the mind, the environment or all three?

Sympathetic neurons pepper the embryos of the jawless fish—Earth’s first vertebrates—and overturn the idea that “fight or flight” was an innovation of jawed vertebrates.

When the postdoctoral fellow is not deconstructing cuttlefish camouflage and dodging ink squirts in the lab, you can find her teaching neuroscience courses in correctional facilities…

We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began.

High-throughput transcriptomics offers powerful new methods for defining different types of brain cells. But we need to think more explicitly about how we use these data to distinguish a cell’s…

Warming seas disrupt the function of neurons — and could seed permanent changes in marine species, according to studies of a circuit that controls digestion in crustaceans.

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

The signal it flags is more likely the result of cherry-picking data, according to the researchers who conducted one of the new studies, but the lead investigator on the original work disputes that…

As part of that ambition, we launched a public-private partnership to systematically evaluate antibodies used to study neurological disease, and we plan to make all the data freely available.

Activity in the tiny brain region helps submissive rodents learn to avoid aggressors, and aggressive mice to curb their attacks, according to two recent studies.

To answer this question, consider the animal’s umwelt, or what it needs to know about the world.

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

To foster discourse, scientists need to account for all the different ways they use the term “representation.”…

The feedback could lead to “novel ways” to conduct studies and reduce health disparities, a National Institutes of Health employee says.

Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.

Of the 92 U.S.-based physicians who worked on the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, 55 of them have collectively received millions of dollars from drug and…

Studies of the oscillations reveal that horizontal and vertical eye movements generate distinct sounds.

The opportunities cater to students interested in careers outside the ivory tower.

Follow these four tips to avoid using the information in problematic ways, including as a proxy for environmental variables.

Schiller, best known for his research on how the superior colliculus controls eye movements, died last month at the age of 92.

The labeling technique trains machine-learning algorithms with larger datasets and less effort than ever before.

Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.

Emerging methods make it possible to combine the two tactics from opposite ends of the analytic spectrum, enabling scientists to have their cake and eat it too.

High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.

Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for…

We aim to deliver insights and tools to build bridges across neuroscience and propel research forward.

In this series of essays, newly published in English, cognitive neuroscientist Stanislas Dehaene taps brain images to help explain new findings.

Feeling sick reactivates “novel flavor” neurons, according to a new study in mice, and points to a dedicated circuit for learning to avoid unsafe food.

The brain may be chaotic. Does that mean our efforts to control it are doomed?

Whereas some mice display hypersensitivity to touch only as adults, others respond that way from birth.

This foundational paper, with more than 1,500 citations, is an important departure from early neuroscience research. Don’t be afraid of the math in the first paragraph.

Neuropixels arrays implanted in people reveal nuances of speech perception and production that confirm results from brain-surface recordings and can even predict what someone is about to say.

The former associate professor of neuroscience is not one to shy away from a challenge, including embarking on a new career at the National Institutes of Health.

The majority of an 11-person committee resigned from the group this week following news that a staff position overseeing equity, diversity and inclusion would not be renewed.

A massive new set of interaction maps illuminates especially high convergence in protein networks related to autism and shows how mutations could disrupt those networks.

Movements that boost activity in the visual cortex of mice have the opposite or no effect in marmosets and macaques, prompting questions about whether mice are a suitable model for the primate visual…

A better understanding of the blood oxygen level dependent, or BOLD, signal requires more support for multimodal imaging studies.

The link reported in prior studies likely reflects confounding factors, which sibling-matched controls in the new work address.

Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.

Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.

Nature - A pioneering ‘connectomics’ collaboration has successfully reconstructed one cubic millimetre of brain tissue, but researchers are still just scratching the surface of the complexity it...

A slew of simple creatures demonstrate forms of learning, making the case for cognitive science to expand beyond the boundaries of the human mind.

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

When I launched my new lab at New York University in 2022, I decided to apply my expertise in computer vision to an urgent problem far outside the brain: climate change.

Working at a biotechnology or artificial-intelligence company is no longer an “alternative career” for researchers with a doctorate in neuroscience—plus jobs, training and funding updates for May.

New mouse models join several studies that could point to novel therapeutic approaches.

The headset combines calcium imaging and electrode recordings to track both the cerebellum and anterior cingulate cortex as mice socialize.

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

The resignation follows reporting by Spectrum and Retraction Watch in October about nonexistent references in the retracted article.

From big-picture debates about theories and terms to practical tips for teaching and writing, our favorite expert-written articles offer a glimpse into what neuroscientists are thinking.

Phosphorylation of the metabolic enzyme pyruvate dehydrogenase inversely correlates with neural activity, offering scientists a tool to study inhibition for the first time.

The retraction follows an editorial expression of concern that the journal applied to the paper in October, seven months after it was published in the Proceedings of the National Academy of Sciences.

Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.

The faked data, which was part of research on the genetic mechanisms of synaptic plasticity, was used to obtain more than $1.4 million in federal funding.

A data sleuth flagged an apparent duplicate image in the 2015 prion study led by neurologist and biochemist Stanley Prusiner.

Efforts to define “frank” or “classic” forms of the condition build on several assumptions that the science has not yet borne out.

The program is funded at $402 million for the current fiscal year, a 40 percent drop from last year.

If the proposal is finalized, two psychedelics — one of which is widely used in basic neuroscience studies — would move into the strictest drug category.

Two recent papers suggest genes can play a significant role, findings that could change diagnosis and treatment of the condition.

The brain may be chaotic. Does that mean our efforts to control it are doomed?

This ongoing essay series will explore questions these technologies raise, as well as opportunities they provide for understanding development, evolution and disease.