aled edwards
@aledmedwards
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Open access science and drug discovery. Founded and (still) direct @thesgconline. My comms folks shudder when I tweet.
Toronto
Joined October 2010
RT @thesgconline: A well anticipated overview highlighting the first CACHE challenge, which brought together 23 research teams from 10 coun….
pubs.acs.org
The CACHE challenges are a series of prospective benchmarking exercises to evaluate progress in the field of computational hit-finding. Here we report the results of the inaugural CACHE challenge in...
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RT @thesgconline: A news feature by @Nature addresses the longstanding issue of unreliable antibodies in biomedical research and highlights….
nature.com
Nature - Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this.
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RT @consciencemeds: Save the date for the second annual Conscience Symposium on Open Drug Discovery! Join us in Montreal on April 7-8, 2025….
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This WD paper reports machine learning applied to DNA-encoded library screening datasets at scale. Bottom line it works. Sometimes. Lots of opportunities to improve. Including by open sourcing models as James has done here.
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The Unites States government is now going to do the grand experiment to test if those loud and opinionated armchair athletes and coaches have what it takes when given the chance to lead the team. I don’t think it’s going to be pretty.
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And I suspect we’d both opt for the train when we get a high speed train between Montreal and Toronto. We can hop on the train with Godot.
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Want to be a fly on the wall in an industry-standard drug discovery program? Join the M4K Pharma monthly zooms. Real pros at work, sharing their expertise to try to invent an open source medicine to treat children’s brain tumours.
M4K Pharma's October Scientific Update meeting is now available online: .In this session, our team provides detailed insights into the latest progress on developing new treatments for DIPG through our #OpenScience approach. #BrainCancer #Medicines4Kids.
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Waiting to board flight to Toronto and just in front of me in line was @FP_Champagne, Canada’s Minister of Industry and other things. He headed to his seat in economy (as did I). Spending Canadian tax dollars wisely. Gotta like it.
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RT @open_fold: #AlphaFold3 is open-source for academic use now! See what our partner, @MoAlQuraishi, has to say about our upcoming OpenFold….
nature.com
Nature - The code underlying the Nobel-prize-winning tool for modelling protein structures can now be downloaded by academics.
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RT @target2035: Just Launched! Episode 1 of the Target 2035 Podcast Series🎧 In the debut episode, @LabScribbles welcomes @CherylArrowsmi1,….
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It’s very encouraging that funders support projects like YCharOS, which does not address hypotheses, but rather does the foundational, but not sexy, work of testing and characterizing reagent antibodies in order to make everyone else’s science more robust and reproducible.
CQDM is proud to announce the funding of a collaborative research project made possible through a grant of nearly Can$1.49M from the Government of Quebec (@economie_quebec). A project of @YCharOS1 in partnership with @mcgillu. 👉
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Congrats to @thesgconline Board member, Dafydd Owen 🏴, for leading the team that invented the active ingredient in Paxlovid, which was awarded a #PrixGalien prize last night!.
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Trump got fewer total votes this election than last. 12 million (!!) Democrats just didn’t show up and vote this time. It would have been landslide Harris victory if they had.
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RT @JonnyRoot_: Steve Kerr on the election. Kerr: “I believe in democracy. I think the American people have spoken and voted for Trump. I w….
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RT @DanielJDrucker: Draining the swamp. Assessment of 614 commercial antibodies, targeting a total of 65 neuroscience-related proteins, dem….
nature.com
Nature - Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this.
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RT @TheNeuro_MNI: Neuroscientist Carl Laflamme describes @YCharOS1, an initiative testing commercial antibodies to determine if they work a….
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Canada and Toronto are great places to go to grad school or to do a post-doc. Just saying.
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A charismatic leader. Economic malaise. Enemies within. Expert propaganda. Angry young men. Demonization of “others”. And voted into power. We’ve seen this script before. C’mon America, we don’t want to watch the sequel.
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Does machine learning work on DEL datasets? Indeed it does. Sometimes.
pubs.acs.org
Target class-focused drug discovery has a strong track record in pharmaceutical research, yet public domain data indicate that many members of protein families remain unliganded. Here we present a...
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