Xing Bengang_ Research Group @ NTU_SG
@Xing_Group_NTU
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Passionate in Chemical Biology, Bio-labeling, Molecular Probe Development, Pharmaceutical Chemistry, Nano-medicine & Kinds of Sports (run by lab staff)
NTU Singapore
Joined November 2021
RT @morellifit: Leaky gut raises your cancer risk by 6x. The crazier part? 1 in 3 Americans walk around with it & have no clue it’s deadly….
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RT @Glaconde34: Long-Acting and Stapled GLP-1R/GIPR/GCGR Triple Agonist for the Treatment of Obesity and Atherosclerosis | Journal of Medic….
pubs.acs.org
Unimolecular multireceptor coagonists have emerged as a promising approach in the development of next-generation GLP-1 therapeutics. Herein, we describe the development of a long-acting and stapled...
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RT @Lumimatlab: Excited to share our latest work on dual-modal photoacoustic and fluorescence probes specifically designed for Cu(I) imagin….
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Looking for PhD/Postdoc Positions in Chemical Biology, Molecular Probe & Imaging, Bio-labeling & Nano-theranostics ? Join my NEW lab at ABCT Department, PolyU Hong Kong. Follow the link to find out more, 👇👇👇
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RT @J_A_C_S: Macrocyclic Phage Display for Identification of Selective Protease Substrates | Journal of the American Chemical Society .@mba….
pubs.acs.org
Traditional methods for identifying selective protease substrates have primarily relied on synthetic libraries of linear peptides, which offer limited sequence and structural diversity. Here, we...
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Nice study for gut microbiome and immune manipulation . .
Led by Nanyang Asst Prof Qiao Yuan, researchers from @CCEB_NTU developed an analytical platform that discovered an alternate signaling pathway between our immune system and our gut microbiome as well as the bacterial fragments involved. Read more:
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RT @Gut_BMJ: #GUTimages from the #GUTRecentAdvancesInBasicScience paper by Gudiño et al entitled. "Single-cell omics in inflammatory bowel….
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RT @CellCellPress: Now online! Regulation of inflammatory responses by pH-dependent transcriptional condensates
cell.com
BRD4 functions as an intracellular pH sensor through a conserved histidine-rich intrinsically disordered region. Inflammation-associated acidification triggers a pH-dependent switch in transcriptio...
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RT @SciencNews: Undruggable ‘disordered’ proteins become druggable with new AI techniques from David Baker. @ScienceMagazine . https://t.co….
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Very long while not to login X/Twitter. coming back as usual now. 🐻🐻🐻🐻.
🧪 What happens when chemistry goes inside living systems?.Discover cutting-edge tools and real-time imaging at the “Chemistry in vivo” session at #ChemBioParis2025 with @dynafluors and @Xing_Group_NTU. 📍 Paris | 🗓 Oct 6–9.🔗 #ChemBio #InVivoChemistry
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RT @jfcryan: Latest lab review- The Gut microbiota-Immune-Brain axis: Therapeutic Implications. Just out in @CellRepMed Well done @kjdorior….
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RT @NatureRevMicro: The role of bacterial metabolism in antimicrobial resistance.
nature.com
Nature Reviews Microbiology - In this Review, Ahmad et al. examine how antibiotics influence bacterial metabolism and how metabolism, in turn, affects drug efficacy and the emergence and evolution...
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RT @J_A_C_S: An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor | Journal of the American Chemical….
pubs.acs.org
Staphylococcus aureus (S. aureus) is an opportunistic human pathogen that causes over one million deaths around the world each year. We recently identified a family of serine hydrolases termed...
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RT @CellChemBiol: Online now! Dynamic PRDX S-acylation modulates ROS stress and signaling by @CBwolfTQ, Saara-Anne Azizi, @shubha_pani, @ch….
cell.com
PRDXs are key regulators of ROS. Qiu et al. report that the entire family of PRDXs is regulated by lipidation. They demonstrate that both PRDX lipidation and APT activity respond differentially to...
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a very cool study. 👍.
Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein–Protein Interactions Using Phage Display | Journal of the American Chemical Society @Stanford @StanfordMed @mbogyo
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RT @Glaconde34: Chemoproteomics-Enabled De Novo Proteolysis Targeting Chimera Discovery Platform Identifies a Metallothionein Degrader to P….
pubs.acs.org
Proteolysis targeting chimeras (PROTACs) represent powerful tools to modulate the activity of classically “undruggable” proteins, but their application has been limited to known ligands and a few...
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RT @NatRevDrugDisc: For readers interested in cancer immunotherapy, this Review in our February issue discusses opportunties and challenges….
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precise pH control for self-reporting Ab-drug release. 👍👍.
🚨Exciting news!🚨 Our latest work is out in @J_A_C_S! A Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody-Drug Conjugates @dynafluors @EdinUni_IRR @abbvie 🧵👇.
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RT @mifridm: Excited to share our latest manuscript in Current Opinion in Chemical Biology. We explore how fluorescent probes reveal antifu….
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Finally, the manuscript is online, thanks for the students' dedication, and certainly, referees' kind recognition. .
Enzyme-Activated Orthogonal Proteolysis Chimeras for Tumor Microenvironment-Responsive Immunomodulation (Bengang Xing and co-workers) @Xing_Group_NTU •
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