DYNAFLUORS
@dynafluors
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Marc Vendrell and many more. Dynamic Activatable Fluorophores: seeing biology and medicine through the eyes of chemistry. Univ. Edinburgh. Views my own.
Edinburgh
Joined March 2016
Our vision is to aid cancer imaging using our Dynafluors tools to visualize the role of immune cells. We could not achieve our goals without the support from the EU and @EdinburghUni @EdinUni_MeetCIR @The_MRC
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Thrilled to share our latest work: Abiotic Transcription Factors by Strategic Insertion of Non-Proteinogenic Amino Acids. Appeared today on @ChemRxiv
https://t.co/jMgfQD6jkF Exciting collaboration with @dynafluors & @Afek7Afek Congrats to Omer, Ferran, and the rest of the team!
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B&B2025 Plenary speakers announced!! Please pencil down these dates in your calendar: 5 and 6 of June 2025. #BandB2025 @BOOMchemistry @dynafluors
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🚨Exciting news!🚨 Our latest work is out in @J_A_C_S! A Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody-Drug Conjugates https://t.co/4NM15VLCWS
@dynafluors @EdinUni_IRR @abbvie 🧵👇
pubs.acs.org
Antibody–drug conjugates (ADCs) represent promising therapeutic constructs to enhance the selective delivery of drugs to target cells; however, attaining precise control over the timing and location...
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Less than 36 hours left to register !!! PSL Chemical Biology comes with an exceptional speakers lineup, in the center of Paris - Register now - do not miss this major #ChemicalBiology event #ChemBio #ChemBioLovers
pslchembiol.com
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Mikala Egeblad: AACR Board of Directors Candidate Dr. Mikala Egeblad (@megeblad), a leading expert in tumor microenvironment and metastasis, is up for election to the @AACR Board—discover her groundbreaking work and vision for cancer research. https://t.co/o0eZXdUCGZ
#Cancer
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What a great pleasure collaborating with Jesús Santamaría and JL Hueso (@INMAdivulga), and @m_carmenortega. Congrats to Nacho, @m_carmenortega, Cath and the rest of the authors for this great work!
Dendritic Platinum Nanoparticles Shielded by Pt-S PEGylation as Intracellular Reactors for Bioorthogonal Uncaging Chemistry (Asier Unciti-Broceta and co-workers) @boomchemistry @INMAdivulga #openaccess 🔓
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Thrilled to share our new @J_A_C_S paper! Arvenin I, a plant natural product, emerges as (to the best of our knowledge) the first-ever covalent kinase activator. 🧬 Check it out! #chemicalbiology #NaturalProducts #KinaseActivator
pubs.acs.org
Despite the unprecedented therapeutic potential of immune checkpoint antibody therapies, their efficacy is limited partly by the dysfunction of T cells within the cancer microenvironment. Combination...
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Excited to share our latest review in @ACSChemRev! Targeted Covalent Modification Strategies for Drugging the Undruggable Targets | Chemical Reviews
pubs.acs.org
The term “undruggable” refers to proteins or other biological targets that have been historically challenging to target with conventional drugs or therapeutic strategies because of their structural,...
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Happy New Year to all of our followers!🎇 Join us for our next webinar on Protein and Peptide Science on 7th February 1pm UK time. Hear from Dr Sona Krajcovicova (University of Cambridge) & Dr Anna Peacock (University of Birmingham). Register here https://t.co/sD1WFCoq1h
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Our paper highlighted in a First Reactions article: Wash-free Imaging in Live Cells | ACS Central Science
pubs.acs.org
Palladium-mediated arylation enables minimal labeling of peptides and proteins with small fluorogenic amino acids for wash-free imaging.
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How about a short read on peptide-based ion channels and membrane carriers to start 2025? Here our contribution @ciqususc with Dr. Alberto Fuertes and Manuel Perez in Current Opinion Chemical Biology. Thanks to Mathew Langton @ChemLangton and Robin Bon! https://t.co/puw6l2Bw4a
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We are delighted to announce Professor Asier Unciti-Broceta from University of Edinburgh will be the BMCS Lecturer for 2024/2025. Since 2014, the Biological and Medicinal Chemistry Sector (BMCS) of the Royal Society Chemistry has endowed an annual lectureship with the aim of
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Looking for an interdisciplinary PhD position at the chemistry/biomedical interface to help develop early diagnostics for brain cancer diagnostics with K. Kurian @r_martin_ @BristolCancer @BristolChem Apply here until 30th January https://t.co/YPmUULI4ZW
findaphd.com
PhD Project - One Inter-Disciplinary PhD Studentship on Early Detection of Brain Cancer at University of Bristol, listed on FindAPhD.com
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So thankful to the @RSC_BMCS for this recognition, which I would like to extend to the @BOOMchemistry team and @EdinUni_IGC colleagues. Looking forward to talking about the discovery and preclinical/clinical development of #eCF506/#NXP900 across the UK!!
We are delighted to announce Professor Asier Unciti-Broceta from University of Edinburgh will be the BMCS Lecturer for 2024/2025. Since 2014, the Biological and Medicinal Chemistry Sector (BMCS) of the Royal Society Chemistry has endowed an annual lectureship with the aim of
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Late-stage labeling to prepare unprotected fluorogenic peptides/proteins via Cys arylation with minimal bioactivity perturbation & suitable optical properties for wash-free imaging in live cells NEW #ASAP by @dynafluors, @JbaraM90 & colleagues Read here: https://t.co/0to9eYtfyo
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This approach enables the generation of artificial fluorescent proteins and the development of biosensors from potentially any protein of interest with minor modifications. @NatureChemistry
https://t.co/x57thl26E1
nature.com
Nature Chemistry - The toolbox of artificial fluorescent proteins can be expanded by engineering mimics of the molecular rotor-based fluorophore found in the green fluorescent protein (GFP) into...
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We have two fully funded PhD opportunities in medicinal chemistry and chemical biology through the EASTBIO BBSRC DTP. Deadline 17th Jan 25 More details and apply below https://t.co/v5VD1kl8DP https://t.co/isfazFDYKU
findaphd.com
PhD Project - EASTBIO-Peptide-based precision anti-infectives for prophylaxis and treatment of foodborne listeriosis at University of Edinburgh, listed on FindAPhD.com
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Our colleagues in the peer review team are looking for an Assistant Editor to join our prestigious in-house chemistry and materials portfolio @ChemEurope
@angew_chem + Advanced journals. The position will be based in Germany. Please like and share! https://t.co/Ic7yGda0b6
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Feel free to share. It will be advertised here https://t.co/oP1rgI2Dor and here @isfgs
@IPSO_PedSurgOnc @Me4Ped @WorldSIOP
@prinsesmaximac @LPTrustUK @DiagnosticGreen @CRCTU @beggs_lab @BWC_NHS @cclguk
@MarkGaze @dynafluors
@angelapolanco16 @AngelbethanyP The future is green.
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We're seeking outstanding applicants for two postdoc positions in my lab - one focused on immunology ( https://t.co/Qz5oe2IpXH) and the other focused on Intestine Chips ( https://t.co/OKGzlHnqwD). Spread the word and apply today! #PostdocPosition #PostdoctoralFellow #Hiring
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