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Cell Reports Medicine

@CellRepMed

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Broad-scope #OA journal from @CellPressNews publishing cutting-edge science across the spectrum of #Translational and #ClinicalResearch | Editor: @DrSaraHam

USA, NLD, CHN, GBR, BEL
Joined October 2019
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@CellRepMed
Cell Reports Medicine
1 month
Xing et al. show BRAF/MEK inhibitors induce glioma cell plasticity, upregulating PD-L1 and suppressing T cells. Artwork depicts tumour heterogeneity as flowers, with PD-L1 as florets and T cell suppression as spent heads. Cover by Yao Lulu Xing.
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@CellRepMed
Cell Reports Medicine
2 hours
Online now: Opantimirs: A class of antagonizing microRNAs that upregulate Opa1 and improve mitochondrial and disuse myopathies
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@CellRepMed
Cell Reports Medicine
1 day
Online now: IgA2+ B cells and IgA2 anti-dsDNA antibodies are selectively targeted by belimumab after rituximab therapy in systemic lupus erythematosus
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@CellRepMed
Cell Reports Medicine
2 days
Connect with us on LinkedIn for curated content, author interviews, and information on editors that may be visiting your city!
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@CellRepMed
Cell Reports Medicine
3 days
Interested in sharing your research at our Cell Symposium in LA?.We're keeping the abstract submission system open for poster and short talk submissions until August 1, 2025. Submit here: @CellSymposia #CSStemCells25
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@CellRepMed
Cell Reports Medicine
3 days
Online now: Recreating pathophysiology of CLN2 disease and demonstrating reversion by TPP1 gene therapy in hiPSC-derived retinal organoids and retina-on-chip
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Corti et al. leverage patient hiPSC-derived retinal organoids and retina-on-chip systems to replicate key CLN2 retinal pathologies, including lipofuscin accumulation and cone dysfunction. AAV9-medi...
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@CellRepMed
Cell Reports Medicine
3 days
Online now: Deep learning for detection and diagnosis of intrathoracic lymphadenopathy from endobronchial ultrasound multimodal videos: A multi-center study
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Chen et al. develop AI-CEMA, a deep learning system for CP-EBUS multimodal video analysis that automatically selects representative images, identifies lymph nodes, and demonstrates expert-level...
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@CellRepMed
Cell Reports Medicine
4 days
Online now: TME-guided deep learning predicts chemotherapy and immunotherapy response in gastric cancer with attention-enhanced residual Swin Transformer
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Sang et al. develop a multitask deep learning model, the residual Swin Transformer network, from radiographic image and clinical data, which allows non-invasive evaluation of adjuvant chemotherapy...
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@CellRepMed
Cell Reports Medicine
4 days
Online now: Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners
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Sun et al. identify PGK1 as a key metabolic driver of diabetic kidney disease (DKD). PGK1 promotes inflammation via both enzymatic and non-enzymatic mechanisms. Targeting PGK1 with small-molecule...
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@CellRepMed
Cell Reports Medicine
5 days
Online now: CAR-T cell therapy and reconstructive oncologic surgery in peripheral solid tumors—A narrative review
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In this review, Knoedler et al. highlight the potential of integrating CAR-T cell therapy with reconstructive surgery for peripheral solid tumors. Combining advanced cellular immunotherapy with...
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@CellRepMed
Cell Reports Medicine
6 days
Online now: Intrinsic chicory root fibers modulate colonic microbial butyrate-producing pathways and improve insulin sensitivity in individuals with obesity
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Omary et al. show that 12-week supplementation with intrinsic chicory root fiber improves insulin sensitivity and cardiometabolic health. These benefits are accompanied by a functional shift toward a...
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@CellRepMed
Cell Reports Medicine
7 days
Online now: Metabolic fingerprinting enables rapid, label-free histopathology in gastric cancer diagnosis and prognostic prediction
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Teng et al. develop a rapid and label-free histopathological method based on metabolic fingerprinting of FFPE tissue using nanoparticle-enhanced LDI-MS. The efficient method enables diagnosis,...
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@CellRepMed
Cell Reports Medicine
7 days
Online now: RANKL/PD-1 dual blockade demonstrates survival benefit for patients with advanced lung adenocarcinoma harboring KRAS mutations
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Li et al. find that KRAS-mutant LUAD resists immunotherapy due to RANKL-driven immunosuppression via PD-L1/CXCL9-11 downregulation and reduces CD8+ T cells. RANKL inhibition combined with PD-1...
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@CellRepMed
Cell Reports Medicine
8 days
Online now: Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma
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Chen et al. develop a chlorin e6 derivative-mediated PDT combined with immunotherapy, incorporating PDT, a STING agonist, and anti-LAG3. This approach optimizes the tumor immune microenvironment by...
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@CellRepMed
Cell Reports Medicine
9 days
Online now: Endoscopic healing in pediatric IBD perpetuates a persistent signature defined by Th17 cells with molecular and microbial drivers of disease
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Persistent inflammation compromises long-lasting remission in patients with inflammatory bowel disease (IBD). Siebert et al. identify a transcriptomic signature of residual disease in intestinal...
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@CellRepMed
Cell Reports Medicine
9 days
Final call: Abstracts for Gene and cell-based therapies are due tomorrow Friday, July 18. Submit now for a chance to present your work at this symposium in LA! @CellSymposia #CSStemCells2025.
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@CellRepMed
Cell Reports Medicine
10 days
Online now: A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer
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Dilasser et al. identified A41 as a specific RAC inhibitor. Chronic administration of A41 exhibits anti-metastatic effects in experimental models of invasive cancers (breast and colorectal cancers),...
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@CellRepMed
Cell Reports Medicine
10 days
Online now: Perioperative administration of CBM588 in colorectal cancer radical surgery: A single-center, randomized controlled trial
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Yang et al. conduct a phase 4, open-label, randomized controlled trial and report effects of perioperative administration of CBM588 in patients undergoing colorectal cancer radical surgery. CBM588...
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