The moment I've been waiting for, to showcase the direct visualization of actin nucleators and their cooperative yet competitive assemblies in the #actin cytoskeletal network!! Check out some of our videos below and supplementary files https://t.co/Y78THcrO07

Excited to share our new study @biorxivpreprint "Cyclin-dependent kinase-like 5 (CDKL5) binds to talin and is anchored at the postsynaptic density via direct interaction with PDZ domains" Instead of a 🧵the paper is summarised in this video. https://t.co/wV3GGokTLV

The multinucleate, multibudding yeast, A. pullulans delivers nuclei into each daughter bud during #mitosis. Petrucco, Gladfelter, Lew et al image #microtubules during mitosis, revealing mechanisms ensuring that most daughters inherit one & only one nucleus https://t.co/BzEtCMbtrf

We’re excited to announce our new paper on Time-deterministic cryo-optical microscopy! This technique rapidly freezes living cells during imaging, adding temporal info to cryo-fixed samples for deeper analysis. Huge thanks to our amazing collaborators. https://t.co/UmfWpUpne2

Geng, Verhey et al find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors https://t.co/8Q2bCzKL2a

“Helsinki has not recorded a single traffic fatality in the past 12 months, city and police officials confirmed this week.” City engineer credits lower speed limits and smart design. I agree. #Helsinki #VisionZero https://t.co/GCTYxz59Td

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15

Realized this morning that my submission got selected @YaleMed Beauty in Science 2025 exhibition! Seeing the live-assembly of filopodia projections by formin mDia3 in mast cells got me really stoked back then! #FluorescenceFriday

I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @ScienceMagazine ! (link at end of 🧵)

Majority of data never get the opportunity to be published. This is F-actin clearly organized in two modes, clusters or meshes, possibly mediated by formins and Arp2/3.

When Ca2+ oscillates, [Ca2+] is the variable. Is [Ca2+] also the control parameter that defines the system's stability? Happy to share our opinions: A molecular systems perspective on calcium oscillations beyond ion fluxes https://t.co/ZmPY5F8wzk

Actin waves + inverted LUTs 🤩 (bonus points if you can guess the cell type)

Unlike eggs and mitotic cells, in adherent interphasic cells the centrosome is NOT positioned by a balance of forces along #microtubules, but by cell shape organization around the #centrosome. New from Schaeffer, Théry and colleagues: https://t.co/8q7GDl5aVG

A long-awaited mechanistic analysis of small GTPase biology and membrane pattern formation by the labs of Peter Bieling and Bill Bement @BementLab https://t.co/E3FidcWRXj

4Pi-SMS and pan-ExM reveal, in a close collaboration with the Rothman lab, a surprising tetraplex organization and self-assembly of rim golgins, which we believe can explain stack formation of the Golgi apparatus: https://t.co/lxWaoCSN8T

Golgi apparatus is a daunting target for imaging for its uniquely stacked morphology throughout 3D space. To see how we combined super-resolution microscopy and biochemistry to study Golgi, please read our manuscript with all supplementary in BioRxiv:

I am happy to share our 5-year's work of manual mapping of all the native proteins in the golgin family, providing the highest resolution atlas of the Golgi apparatus to date! Yes, we can distinguish proteins at different cisternae.

Fresh from the press with @NaturePhysics: How do we leverage a cell's self-organization to make it change its shape into a square? Check it out here: https://t.co/Ni9gpBqYDx @PhysOfLifeLMU @FakhriLab

And finally in print https://t.co/tq2n2Yubt7

What do action potential, hearing, calcium oscillations have in common? A periodic, synchronous opening of ion channels that we do understand. Our latest work proposes an alternative perspective for these conceptual problems beyond an ion flux-centric view. Feedbacks welcome!

STIM1 and Endoplasmic Reticulum-Plasma Membrane Contact Sites Oscillate Independently of Calcium-Induced Calcium Release. Contact site oscillations, hard to see but we think are real!