A much too flattering profile of yours truly. A testament to Vivien’s writing skills to actually make it sounds like I (1) am interesting and (2) know what i’m doing 🤣

Larry Page & Sergey Brin had the PageRank paper (the algorithm behind Google Search) rejected. A reviewer called it “disjointed.” Geoffrey Hinton's Dropout was rejected for being “too simple.” I often feel the academic peer review is like a random process, especially when a

Mack's Mets: ANGRY MIKE: 2025 PROSPECT REPORT: ZACH THORNTON :

Electromagnetic fields clearly influence biology. The question from my colleagues has always been “What’s the mechanism”? Sensory magnetoreception in birds opened the door into probing these mechanisms through magnetite, but as we build out quantum-scale models & technology,

Incredibly exciting announcement from the brilliant @doristsao about her new institute focused on consciousness and intelligence!

New work describes our efforts to achieve CRISPR editing of the mitochondrial genome. https://t.co/L98rtFj5Yq The CRISPR toolbox has revolutionized the study of nuclear DNA, but the mitochondrial genome (mtDNA) has remained out of reach, mainly because there are no known ways

4K quality. 50 frames per second. Synchronized sound. LTX-2 brings full production capability into one complete model. And it runs on a fraction of the compute power.

https://t.co/eAXy8rexbo

Can someone please connect me with someone at FDA CDER (or with expertise thereof) to discuss the pathway to approval for n-of-1 & n-of-many ASOs? I've got some pretty technical questions too involved to tweet out here.

Can someone please connect me with someone at FDA CDER (or with expertise thereof) to discuss the pathway to approval for n-of-1 & n-of-many ASOs? I've got some pretty technical questions too involved to tweet out here.

They did an 8000 patient clinical trial at a cost of just $1.3 million by incorporating the trial into routine clinical practice. #ASH25 Traction trial. Would have cost >100 times more ordinarily. We need to completely revamp the clinical trial bureaucracy.

Name some labs you think are doing truly frontier work in biology that you think likely I haven't heard of (ie don't say Mike Levin, Ed Boyden, Brian Hie etc)

Method of the Year 2025: In his Comment, Moritz Helmstaedter @mh_lab looks into the future of connectomics and the feasibility of scaling up to larger brains. https://t.co/iafRUt3LjT

Method of the Year 2025: In his Comment, @janfunkey discusses current challenges in connectomics, which is time-consuming and labor-intensive. He focuses on proofreading and discusses how automated models might be further developed to embrace uncertainty. https://t.co/uL5ynHxB9B

Fascinating @ScienceMagazine article on magnetosensing and its unexpected ties to mechanobiology. A pigeon’s semicircular canal in their ears, long regarded as a fluid-filled labyrinth that acts as a kind of gyroscope for orientation (much like our own) - is receptive to weak

Putnam, the world's hardest undergrad math contest, ended 4pm PT yesterday. By 3:58pm, AxiomProver @axiommathai autonomously solved 8/12 of Putnam2025 in Lean, a 100% verifiable language. Last year, our score would've been #4 of ~4000 and a Putnam Fellow (top 10 in recent yrs)

"In the end, I have come to realize that being authentic at work is not a weakness, but rather a strength." #ScienceWorkingLife https://t.co/xXF9s1QUnj

I saw in a post elsewhere that PubPeer blocks itself from search and indexing engines, so apparently neither Google, nor LLMs know what's there. Is this true?

I was supposed to be in Philly co-hosting an AI in Cell Bio workshop with David Van Valen today but got derailed by an awful cold. Feeling bummed about it all and then this photo I took at an ASCB 11 years ago popped up on FB. I hope my ASCB friends are having a great time!

I saw in a post elsewhere that PubPeer blocks itself from search and indexing engines, so apparently neither Google, nor LLMs know what's there. Is this true?

We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect. Full study now online at Cell @CellCellPress Paper 👉 https://t.co/nMpVaiTCni Thread for a synopsis 👉 https://t.co/X8QDQpRGTQ

After seeing that high-dimensional unit balls hide almost all their volume in a thin shell, here’s an even crazier sequel: A high-dimensional Gaussian is not a cosy bell with mass cuddled at the peak, it’s basically empty in the centre, with almost all the probability living in

Huh TIL Sony has re-used our years-old "PSSR" super-resolution algorithm name to instead refer to their proprietary gaming super-resolution algorithm.