Stephen Griffin
@SGriffin_Lab
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Professor of Cancer Virology | Viroporins, Antivirals, Viral Oncology, Immunotherapy | Own views | @IndependentSAGE @LongCovidKids @projecthalo #VaccinesPlus
University of Leeds, England
Joined April 2018
The vax hesitant need knowledge and support, not vilification. Pushing Anti-vax 💩 is unforgivable Here's my attempt at an accessible vax FAQ Thanks so much to @LongCovidKids, @Nat_Elodie_A_N and @jneill for brilliant and patient help with this! 🙏❤️ https://t.co/pn5Vll7t1F
longcovidkids.org
6th January 2023By Dr Stephen Griffin Associate Professor of Viral Oncology in the School of MedicineUniversity of LeedsLong Covid Kids Expert and ChampionWith data analysis from James Neill Consul...
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AI agents aren’t failing for lack of IQ—they’re failing for lack of context. The winners will nail the context layer: clear objectives, permission-aware access to the right content, and workflow-specific tools. Build agents that know your business, not just the internet.
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BA.3.2 sequences from the Netherlands 🇳🇱 were collected in November/December and encompass BA.3.2.1.1.1 (RD.1.1) 2x BA.3.2.1.1.2 (RD.1.2) 2x BA.3.2.2.2.1 (RE.2.1) 1x BA.3.2.2.2 (RE.2.2) 18x
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Great visual summary of the BA.3.2 family and recent sequence count from Europe here by @snpoehlm.
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5 out of 36 (14%) sequences submitted from Scotland 🏴today are BA.3.2.2.2/RE.2
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Oh, and if you want to read about the reality of masks and airborne transmission, look no further than this... https://t.co/T6rmc0ER0E
journals.asm.org
SUMMARY This narrative review and meta-analysis summarizes a broad evidence base on the benefits—and also the practicalities, disbenefits, harms and personal, sociocultural and environmental impact...
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I am NOT infected & out about - so please don’t have a go at me for wearing a mask. Recent updates on 😷 seem to added to the stigma, mask wearers face. I choose sensible precautions to reduce risk of #Flu & any other 🦠 #PublicHealth 🙏 @UKHSA
#Disability #FridayFeeling
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During this Flu surge, wearing a mask will save lives and protect the NHS. It's a small act which can make a huge difference. If the Government is anything but completely clear about these facts, it risks repeating the mistakes of the pandemic. https://t.co/BwtOeKAL2P
theguardian.com
Number of people in England being treated remains at record level for this time of year with daily average of 2,660
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@BigBadDenis Public health in Japan and even the UK has reacted to their wild waves of influenza, driven by "sublcade K" ("Kangaroo variant" ?), with mask mandates in healthcare. They have already driven cases sharply down in Japan. It's clearly not over here - when will @VicGovDH act?
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A pale horse with a pale rider takes the reins at CDER
NEW: I dug deep into new top drug regulator Tracy Beth Høeg's record at the FDA so far, talked to agency staff, and even found some old and interesting blog posts, to get a sense of how she'll lead the drug center. TLDR, staff are worried. More here: https://t.co/jJfDhy15pP
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23. We remain in a scenario, entrenched by past actions, where any changes are met by the right wing press as an attack on our freedoms. It's a simple matter of balanced consideration. Question is, do we want to remember these lessons, hard-learned by 100s of 1000s of deaths?
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Hollywood Animal is available with 25% off. Play “The Stuff That Dreams Are Made Of” new update now!
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22. Remember the flu waves in 2020/21? No, because they didn't happen, despite not acting against airborne transmission. The rebound wave in 2022 could have been mitigated by ramping up vax, masks, clean air, but no, that's not "normal". There's no humane sick pay either.
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21. Ultimately, we need Govt, public health, and public opinion to cause a paradigm shift where we start taking infectious diseases seriously. Why do we tolerate "winter pressures" EVERY YEAR?! They are predictable AND preventable. The investment would more than pay for itself...
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19. Put it this way, countries in SE Asia have embraced this philosophy for good reasons, as @globalhlthtwit rightly points out, relentlessly. They coped with SARS1, SARS2, avian flu, Nipah, etc...they know their onions! Just compare the death rates, folks. 20. Immunity debt, no.
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18. Needless to say, the Healthcare/NHS IPC refusal to act against airborne infections is a nonsense. People would be less upset if you admitted your mistake, apologised, and took action now. Reintroducing mask mandates, too late, wrong masks, and piecemeal just compounds this.
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17. Think "Swiss Cheese" - no single measure is enough on its own, no single person will effect change at scale. BUT, individual acts can have both good and bad consequences. Balance risk, vax status, time spent, ventilation, the activity in question, and who else is there...
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16. What we need is information regarding risk (ventilation ratings, prevalence, etc) and to drop the ridiculous persecution of those who act to both protect themselves and others. This is a trivial act, a minor inconvenience, you don't know who you're sitting next to on the bus.
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14. The narrative that "masks don't work" not only denies physics, but is clearly biased towards fatalism, individualism, and libertarianism. How convenient to have something you don't like rubbished by "experts"...I mean, come on folks... 15. We don't mostly need "mandates"...
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11. Airborne viruses include, but are not limited to: SARS2, influenza, RSV, measles virus, M-Pox (likely)... 12. Yes, virus particles are smaller than mask pore sizes, but aerosol particles are NOT. 13. Masks aren't sieves, they r multi-layered & chemically/physically optimised.
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9. Respirator (FFP2/3) masks, well fitted, DO protect the wearer as well as exerting source control. Surgical masks and, to a very limited extent, "face coverings" will restrict/protect from droplet-borne viruses. 10. Airborne transmission means FFP2/3 masks are gold standard.
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7. Specifically, mask RCTs are inherently flawed, source control must be considered alongside protection. 8. RCTs can't account for complex behaviour. 8. Meta-analyses & systematic reviews are defined by their selection criteria, study weighting, and evidence hierarchy/idolatry.
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