RFK Jr. went on national TV and spouted egregious, dangerous falsehoods about vaccines. As a parent and infectious diseases doctor, I couldn't stay silent. @FoxNews might not fact-check him, but I will. I've reviewed the trials. I've catalogued them. I have receipts. 🧵

Alarming @statnews report on FDA political interference. Career scientists are being asked to find data supporting predetermined conclusions on autism treatments, vaccines, SSRIs - the opposite of how science works. We need evidence-based regulation, not regulation-based

I also wrote a piece about this unpublished study here: TL;DR the sensitivity analysis didn’t redeem it, contrary to what’s been claimed https://t.co/oQ6dvX8vAQ

If you want to learn how to critically analyze a vaccine study and learn how to identify detection bias, surveillance bias, and unadjusted confounders, be sure to follow @jsm2334 (Director of Biostats) and read his piece on the Henry Ford study that’s fraught with all of them.

Yep! She is saying what I’ve been saying all year about how RFK approaches science like a lawyer trying to prove a predetermined conclusion rather than collect data to test hypotheses. He “does the studies to make the proof”, which is a Freudian slip that reveals how he thinks

UPDATE: some of the RIFs have been rescinded. Think about what it’s like to be at CDC. It’s like living with an abusive partner that attacks and then takes back some of the abuse. That doesn’t make the partner less abusive. Sending strength to CDC staff held hostage.

New: The CDC’s flagship publication which reports on public health threats and trends has been essentially rendered inoperable by cuts, sources tell us. I spoke with its former EIC about what this means for the public health of America:

I just want to emphasize: This is not normal. This is unprecedented. And it is chaos. This morning my colleagues -- who are working quite hard -- reported that the White House had decimated CDC offices related to injury prevention, respiratory disease surveillance, and chronic

Sec. Kennedy holds up this non-peer-reviewed preprint as a "rigorous scientific framework that substantiates" his interpretation. But it is not a mechanistic paper, but an explicitly biased narrative review that evaluates studies primarily by agreement with its hypothesis and

CIDRAP Op-Ed: Why the CDC director is wrong about the MMR vaccine by @jakescottMD A call to develop separate measles, mumps, and rubella vaccines to replace the combined MMR shot is not backed by evidence. Here are the facts. https://t.co/VeJku03xZ6

This study by Ota and colleagues (raised at the 9/19 ACIP meeting) claims spike in cerebral vessel walls 17 months post-vaccine but has significant limitations. Just 19 stroke patients, no healthy controls. Their test flagged 2 of 3 unvaccinated patients as positive, which raises

This study by Krauson and colleagues detected vaccine mRNA in hearts of 3/20 deceased patients, but only in areas with pre-existing heart injury that occurred before or at vaccination. The injury was from other causes (heart disease, hypoxemia). The vaccine didn't cause the

EMA - Comirnaty Public Assessment Report (radiolabeled LNP study) Injection site and liver identified as the major sites; "The greatest mean concentration was found remaining in the injection site at each time point in both sexes. Low levels of radioactivity were detected in

Some sources: EMA - Spikevax Risk‑Management Plan (nonclinical biodistribution) “Highest mRNA concentrations were at the injection site, followed by proximal and distal lymph nodes…consistent with distribution via the lymphatic system…only a relatively small fraction

6/ As Drew Weissman noted: “No vaccine was tested more extensively than the RNA vaccines, and no vaccine was given to more people than the mRNA vaccines, and they were found to be incredibly safe.” We want vaccines to work locally to generate immunity. The data show that’s what

5/ Other concerns raised at ACIP deserve context: "DNA contamination" - Trace DNA is expected in many vaccines made in cells. WHO set limits of 10 nanograms per dose for vaccines from continuous cell lines after decades of safety data. The cell-based flu vaccine (Flucelvax)

4/ Biodistribution in rats at 48 hours (radiolabeled LNP lipid, microgram lipid-equiv per g or mL, higher dose/body weight than humans): Injection site: ~165 Liver: ~24 (7x less) Brain: 0.068 (2,400x less) Heart: ~0.6 (300x less) Trace amounts in other tissues are expected for

3/ The "706 days" claim refers to spike PROTEIN in some patients, not mRNA. These are completely different things. mRNA degrades quickly - detectable in blood for days, in draining lymph nodes for weeks. Drew Weissman, who won the Nobel Prize for developing the modified mRNA

2/ In vaccine biology, "local" means the injection site muscle and the lymph nodes that drain it (your armpit for a shoulder shot). That's where vaccines are designed to work. Regulatory studies confirm this: highest concentrations remain at the injection site. Small amounts

U.S. Exclusive: Venture-backed PR software startups Propel, Signal AI announce “strategic partnership”

The mRNA from COVID vaccines primarily stays local at the injection site and its draining lymph nodes. I understand why this has become controversial and confusing. There's a lot of scary information out there. I'll try to clarify a few things: 🧵

1/n Trump admin set to tie Tylenol to autism risk, officials say…but my view: the published evidence is not very compelling with largest study finding no association, and a systematic review showing some studies linking it other not. This needs reframing