Euan Arnott
@Nucleocapsoid
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Joined September 2022
Pinning this to help convert between multiple alternative numbering systems in use for influenza H5N1 hemagluttinin.
In addition, we have made a page to help convert between the many confusing numbering schemes used to name HA mutations: https://t.co/IkizgoNIZ7 (Throughout we use H3 numbering, but other studies use other schemes)
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@HNimanFC Ongoing survey of avian influenza in 🇨🇦wild birds, both dead and alive, since 2005. A significant effort. But BC and Yukon, covering 🇨🇦 part of Pacific flyway, were seriously under-sampled in 2024 and 2025. https://t.co/Np79W98bA0
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Great talk from @ukhadds. Key takeaway for school IAQ: Viral decay of Flu is driven by humidity, while for SARS-CoV-2, it's CO2. Reduce the aerostability of both viruses by keeping mid-level humidity ~45% & CO2 as low as possible & <800ppm @CAPublicHealth
I’ve also uploaded the presentation about our research that I gave at the conference to my YouTube channel. https://t.co/oiwRfmsVhf
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Long, but not hard work to read - and *well worth reading* because it puts all the currently known story in one place. The point about diagnosis delay and hospital infection control *before* H5 is known are especially relevant in an ONGOING way!
#H5N5 #H5N1 #H3N2 @CDCgov @USDA ⚠️⚠️⚠️ Update: What we know about the WA H5N5 case Here’s a rundown of what we know for sure about the H5N5 case in Washington, along with what we might also surmise. There are some real red flags here.🚩 There are indications that public health
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Another good point! A bit like how a *human* can fly an awfully long way during incubation period too. But yes, we are cheating rather by using jet engines...
@Nucleocapsoid We also don’t appreciate how fast birds can fly when they have the mind to. Tundra swan can hit on the order of 90 kmh. Individual tracking data⤵️ They could get infected just before starting, and cover a lot of ground/water before getting sick https://t.co/6Y6JHzd9K2
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Interpreting liver blood test results can be challenging. This article proposes an updated approach to managing abnormal test results, underpinned by new evidence Includes a visual summary #BMJInfographic 🔗 https://t.co/QLrTJlDI1H
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Excellent thread by @snpoehlm summarizing their recent BA.3.2 study. Two BA.3.2 (of 67 total) from Sydney today, continuing its creeping geographical spread. @siamosolocani points out they're related to other NSW BA.3.2, so this is local spread, not a separate introduction.
Our recent study on BA.3.2 is now available. Thanks to Markus Hoffmann, Lu Zhang and @behrens_georg for the great collaboration. Here’s a brief summary of our findings
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May not be literally this specific Tundra Swan that carried H5N5 down to WA this Fall, but whatever migrant bird did had to TOLERATE HPAI well enough to travel while sick? E g. Gannets seem to die fast? Of course, local spread after travel can be in more fatally affected birds.
@HNimanFC Tundra swan is a candidate But still that separation between eastern & western pop’ns Likes estuaries, like the one at in Gray’s Harbour County, at end of Chehalis R Known to winter in Chehalis R valley https://t.co/Wz6QYbi9MD
https://t.co/8c0aGGUwxr
https://t.co/zTrRJxUn7Y
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Here's a tragedy: A teacher has recently had a Covid infection. It's the third time that they know of. They have, once again, been very ill. They are concerned about the impact of multiple infections on their health. They feel their baseline health has deteriorated. 1/🧵
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PB2 mutations: Note: A/Washington/2148/2025 | Host: Human; Collection date 11/10/2025; highlighted in green 2/n
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A/Washington/2148/2025 | 11/10/25 H5N5 A6 geno N5 1346 1344 A/Ringed_Seal/NU/FAV-0410-3/2024 A/Northern_Fulmar/NU/FAV-0290-1/2024 1343 A/Great_Black-Backed_Gull/NS/FAV-0188-9/2025 A/Great_Black-Backed_Gull/NS/FAV-0188-8/2025 A/Great_Black-Backed_Gull/NS/FAV-0188-6/2025
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@danwalker9999 The top 2 N5 samples are from Nunavut! A/Ringed_Seal/NU/FAV-0410-3/2024 A/Northern_Fulmar/NU/FAV-0290-1/2024 Both dead at - Resolute Bay
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"In conclusion, in this series of COVID-19 patients with thrombocytopenia, we observed a decrease in bone marrow MKs, an increase in emperipolesis, and the presence of SARS-CoV-2 proteins in bone marrow megakaryocytic cells. Further work should address the issue of SARS-CoV-2
jthjournal.org
Thrombocytopenia and altered platelet activation are correlated with COVID-19 severity and mortality. COVID-19 patients have modifications of the platelet and blood-circulating megakaryocyte (MK)...
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@Nucleocapsoid @DuckSwabber The top 2 N5 samples are from Nunavut! A/Ringed_Seal/NU/FAV-0410-3/2024 A/Northern_Fulmar/NU/FAV-0290-1/2024 Both dead at - Resolute Bay
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Epidemiological and virological update on the emerging SARS-CoV-2 variant BA.3.2 - The Lancet Infectious Diseases
thelancet.com
The constant emergence of novel SARS-CoV-2 variants has driven the COVID-19 pandemic and sustains the current endemic. Saltation variants, such as BA.2.86,1 encode highly mutated spike (S) proteins...
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1/ Epidemiology: BA.3.2 gained a strong foothold in Western Australia, where it may be on track to dominance. More recently, BA.3.2 also has re-appeared in South Africa, the Netherlands, and Germany, and has made its first appearance in Slovenia, New Zealand, and the UK.
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3/ When examining plasma from individuals who received the JN.1-adapted vaccine, we observe similar levels of antibody evasion for XFG and BA.3.2. This is consistent with earlier studies.
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6/ The new LP.8.1-adapted vaccine markedly increases levels of antibodies that neutralize XFG, while this effect is substantially less pronounced for BA.3.2.
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