Ruxandra Teslo 🧬
@RuxandraTeslo
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Genomics PhD 🧬 @sangerinstitute | Somatic Evolution in Aging & Cancer | long- form https://t.co/ipFMYGuR84 | Emergent Ventures | views my own
Joined January 2020
One's 30s are a crucial period for professional advancement. Especially in so-called "greedy careers": those where returns to longer hours are non-linear. But one's mid 30s is also when most women's fertility starts to drop 🧵.
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It's ethical to cure your own cancer. It's ethical to cure your own cancer. It's ethical to cure your own cancer. There's no debate to be had.
A scientist who successfully treated her own breast cancer by injecting the tumour with lab-grown viruses has sparked discussion about the ethics of self-experimentation
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I hadn't realized this but Romania's next president was 1st in the world in the International Maths Olympiad 2 years in a row with maximum score
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My take on this is that she should quit school, band together with other kids like her and learn stuff on her own. There’s no “system” for the exceptional, people need to realise this and stop asking a system to do what a system can’t do by definition
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@typeclonghouse @animalologist What? What could they possibly be doing lmao. Also you realize there's dirt everywhere.
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This is so bad. 1) no one will be swayed in their vote by this endorsement. It's pure virtue signalling. 2) it will just make ~ half of the voters distrust scientific institutions (there's even a study showing this is what happens).3) how could a political endorsement be.
Scientific American endorse Harris. Which is good and obviously a pro-evidenced based and scientific stance. Cue: all the data bros going eeeuuuhh science isn’t political and meeeeeh science shouldn’t take sides waaaah.
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This rings so true. Many of my friends report being told by their therapists that their partners/ relatives/ friends are narcissistic/ manipulative / egocentric. At some point it dawned on me this is statistically impossible unless smthing like 50% of the population is simply too
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Unpopular opinion but I don't think we should do wealth transfers to people who'll pursue one of the most stable and remunerative careers. Fund people who would take risks they wouldn't have otherwise taken.
Beginning in the fall of 2024, Johns Hopkins University will provide tuition-free Medical School for most medical students and expand aid for future nurses and public health pioneers. Learn more:
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I love how Taylor Lorenz simultaneously thinks not wearing a mask outside is a grave transgression *and* posts what are essentially incitements to murder of insurance company CEOs.
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I just was informed about the extent of science cuts. This is tragic. It's going to be very very very bad. I hadn't realized how bad it was. That being said, I maintain what I said which is that science should have never entangled itself with politics.
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I can’t imagine a more efficient way to waste smart people’s talent than encouraging them to become competitive chess players.
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Girls can wear the same dress actually and nothing bad happens. I do it all the time and generally speaking ppl think I look good. Also, men generally don’t care how many times you were the same dress. So it’s all in ur head.
Male privilege is wearing the same outfit multiple times to events while girls cant wear the same dress twice no matter how cute it is.
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It’s notable the centre right party in UK celebrates not the possibility of achievement, but rather getting by on a stagnant and insufficient median wage by saving and not complaining. Highest virtue the youth can attain is not bothering the older rent seekers.
Katy works for me. She is single & earns less than 30k, rents a room for £775pcm in Central London, has student debt, £120 a month on travelling to work saves money every month, goes on foreign holidays & does not need to use a foodbank. Katy makes my point really well.
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In order to do anything worth doing in life, you need to be a bit delusional and actually really believe in that thing, in a way that might seem irrational from the outside. This takes courage. Spreadsheet morality (80k hrs careers ranking) & its cousin, optionality obsession,.
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There are 2 reasons I changed my mind on having kids:. 1) I like my bf. He’s a combo of pragmatic+ strong & emotionally intelligent. I also trust that whatever happens he’s gonna find a way to sort it. : He’s gonna actively take part in parenting & not just leave stuff to me.
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I Genuinely think understanding how markets work should be required from anyone who studies anything related to society.
We are all doing the same job. We teach the same number of classes. I don't think my labor is worth $20,000 LESS than that of my econ colleagues. More money please.
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As someone who was born and raised in an ex-Communist country, I am always surprised how little regard young Westerners have for their magnificent civilisation. There were a lot of mistakes, indeed, but I FIRMLY believe all alternatives are worse. Romania is a small country. .
Over the past 24 hours, thousands of TikToks (at least) have been posted where people share how they just read Bin Laden’s infamous "Letter to America," in which he explained why he attacked the United States. The TikToks are from people of all ages, races, ethnicities, and
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My Stance on why I'm on Twitter but not on Instagram
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I have become very anti credentialism pilled and I basically think radically expanding uni enrolment has been one the largest mistake in recent decades, with profound consequences. We have basically expanded a class of rent seekers. I think going to.College is still the.
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This is a strawman intended to make everyone who believes in commitment and love look like a naive idiot. Ofc everytime we start dating someone we do such calculations in our brains. The whole point is that:. 1) after this stage, commitment means you choose to view someone as
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The whole proposing thing is a very American thing. In Romania, arguably more trad, women just decide they wanna marry you and they sort of push you into it. This is how my parents & most ppl I know did it. There’s no big “oh no he hasn’t proposed to me” thing.
Proposing to a man is one of the most pathetic things a woman can ever do. Do not do a man’s job for him ever. Also fyi causally dating multiple men simultaneously without the intention to marry is the hallmark of modern hook up culture which is finding women lonelier and more.
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I am not a doctor and not giving advice here, but this has been blown entirely out of proportion. The number of extra mutations with age is still very small and most of them will not have any impact. It has been linked to slightly increased risks of various disorders, but these.
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I genuinely don't have have a mental model of someone who googles "who is Donald Trump" on election day.
future of democracy depends on the people googling "who is donald trump" at 9:30 AM on election day 2024
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I understand that getting a health claim denied is personally devastating, but without denying claims, is the insurance industry even viable? It seems to me like there's a lot of rent seeking in healthcare and some procedure prices are too high, but is this the fault of insurance.
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This is a great explanation of PCA that combines Maths with intuitive understanding.
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I've written a lot abt the need to advance the science of fertility so women can take control of their reproductive timelines & have how many babies they want, when they want. This is feminism. What the article below is, from a self-proclaimed "feminist", is nihilism. Debunk 🧵
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I heard medieval peasants also performed less emotional labour for their kids than we do today.
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@StrangVirusLab @alanlparker What about the ethics of dying? People should be able to try if they are adults and willing to.
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Because they are the jobs that pay well in the current environment. I can’t believe we need Girard or whatevs to explain this 😣.
Why do elite colleges pump students into the same five industries: law, medicine, tech, investing, and management consulting?. For answers, let’s turn to the philosopher René Girard.
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Reading Crime & Punishment only when the murder rates are up
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I mostly think trad/ anti-feminist women have no idea what they’re talking abt. No, having a podcast as a uni educated woman, where you get to satisfy your intellectual needs, does not make you trad. I have spent numerous summers in an actual trad small town in Romania. I have.
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What billionaires donate to highly correlated to what their wives want. See Zuckerberg who donates to Science because of his amazing wife. We need a Bene Gesserit thing where we train the future wives of billionaires so they make wise decisions.
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“Any system that is not explicitly pro-Weird Nerd will turn anti-Weird Nerd pretty quickly.”. My essay on why those looking to create/improve intellectual institutions need to take Rux's rule into account -- with loads of references to Katalin Kariko.
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The whole engagement ring discourse would make sense in a society in which women didn’t have access to household finances. But given that ur money is gonna be shared, whatever price is paid for the ring is not really a “gift” from ur husband, but a dent in ur joint future wealth!.
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The reason why ppl are reacting so negatively to the Harvard people clinging to their credentials w/ their teeth is in large part the hypocrisy of it all. These top unis & their graduates have made it a habit to pretend they are anti elitist. But their very existence is an.
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I find it a bit weird that people consider PhD students at top unis “elites” ( a big part of right wing discourse is focused against these “elites”). There’s an entire actually elite world I was not aware of before going to Oxford. The actual elites don’t do science PhDs, lol.
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I wish more Biology textbooks (and lectures) would take a "historical" approach to teaching biology. The Biology of Cancer by Weinberg is the only one that comes to mind that does this well. Understanding how people came up with an experiment, the available methods at the time
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I suspect many missed opportunities in life are downstream of the fear of appearing to be “cringe”.
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Blackpill for me was when I realised Both the Left and the Right (and especially people in culture wars) use the cover of concern for poor people to discuss what are fundamentally upper middle class -specific concerns & angst.
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This is how people operate when they don’t believe in anything. If you believe in a goal or a mission (in this case a relationship), you become delusional about it. I am deluded about my work and my love. I romanticise them and am crazy in it. I’m a warm blooded animal.
this is the way most people operate, just nobody likes admitting it to themselves.
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I'm confused by how many people think both of these things:.a) we need more children for future economic growth. b) AI will take over most jobs. It's either one or the other.
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Safetyism is strangling progress. Chat I had with a brilliant scientist today (postdoc):. “I feel like I’m no longer doing science. My job has become shuffling around ethics and compliance documents. It’s strangling our science. I am depressed. It’s like they’re trying to stop us.
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They have new evidence abt him engaging in human trafficking, rape and organised crime. What Romanian news outlets describe: taking advantage of poor, young naive women and promising them relationships in UK in order to recruit them into prostitution. This happens quite a lot.
BREAKING: Andrew Tate and brother Tristan arrested in Romania in human trafficking probe
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My granddad looking good after a triple cardiac bypass at 84 and getting surgery for early lung cancer. Long live the Industrial Revolution and modern medicine.
The industrial revolution is the best thing that ever happened to humanity. Ted Kazinsky was a fucking retard.
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I obviously disagree with this and think free speech is above all. But the thing ppl who care abt free speech should wonder where our culture went wrong such that decent but not genius guys like Walz, who simply absorb the surrounding culture, haven't internalised the.
Tim Walz: “There’s no guarantee to free speech on misinformation or hate speech and especially around our democracy”
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As I keep saying, the scarcest resource in today's world is courage.
"An A+ Democratic Senate source of mine reckons that, of the 51 Ds, no more than half a dozen believe he still has a plausible chance in November and want him to stay in the race. The ratio on the House side, as best as I can tell, is roughly the same"
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Whenever ppl talk abt how bad the American healthcare system is (and it has problems) & how great the NHS is, I try to remind them that it’s American money that fuels most of drug discovery. Europeans then get these drugs due to this free riding. Everything has a cost.
@Altimor Interesting piece in @TheEconomist on Europe as the free-rider continent (– you can go over the paywall by disabling JS). My hack is to enjoy the European lifestyle while working for north american companies remotely.
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The appeal of Huberman, in short: He combines looking like a strong man who can handle gorillas with a "oh my soul was in pain and I discovered myself via therapy" vibes. Strong implication he's waiting for "that woman" to replace the therapy as the fix and help him get over.
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I promise I've read other books, but I only recently realised how real Hermione was when she told Harry that courage is more important than books & the significance of her being a Gryffindor and not Ravenclaw. The more I spend time among smart ppl, the more I realise how rare.
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I don’t think the purpose of academia is to achieve justice. The purpose of academia is to get closer to the truth. Doctors should treat a patient independently of their moral failings (they should cure a murderer); Academics shouldn’t cast moral judgements on their findings.
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I was saying this exactly 2 years ago when it was highly unpopular and Evth since then has proven me right. Science aligning itself with politics has hurt it. And people at the top like Holden are responsible for it.
Since when do science magazine editors get to decide which policies are acceptable and which aren’t (& with strong words like “permissible”) ? That’s the purview of politics. Their only job is to make sure that they publish high quality science.
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The cost of freaking out about AI . I owe so much to @ylecun & @beenwrekt . Last year, after chatGPT 4 was launched, I had a month or so of extreme anxiety. I hadn't engaged with doomer arguments before, so they sounded extremely appealing & new. Everyone on Twitter was extremely.
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The books I hope to read in 2023:. Jan: The Bible .Feb- Dec: Trump’s The Art of the Deal.
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bf is in SF and he reports: "There are a lot of people here like you. They have the autistic gaze and walk around looking confused".
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Type of guy who fine tunes his classics fiction reading list according to current events, so that he stays relevant
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I just found out dentist training takes 8 years in the US. In Romania it’s 5. Are dentists in the US so much better? How many jobs are like this, where we impose an arbitrary (and high) threshold for training?.
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If I had to design an intervention that would maximally hurt trust in science without achieving anything pragmatic, it would be having a science affiliated publication endorse a political candidate in the current environment.
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Many ask why medicine is not progressing faster. I go through biology history, argue against the talent/not enough math theory, conclude it's a lot due to slow feedback loops & why we need to make clinical trials faster. Excerpts:. "A version of the.
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This is how the brain of a thinking person works & Thiel, whatever else one might think of him, is a thinking person. You can be pro-capitalist and understand that if a part of a system (e.g. housing) is broken, people won't buy into it.
Wild. This leaked email from Peter Thiel really doesn’t jive with my understanding of his politics that was mostly incepted into my brain by the media.
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There's probably a middle ground to this but I know 2 Romanian men who underperformed in school despite being very smart (both computer scientists). Their entire life changed post taking ADHD medication in UK. I mean not just productivity, but also better mood etc.
23 Percent of American 17-year-old boys have an ADHD diagnosis. Stop. Medicalizing. Boyhood.
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I just had non alcoholic beer for the first time and I realized it's basically just as good as normal beer. Like why do people have alcoholic beer?.
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He treats my interests/ career w/ great respect and has a lot of understanding for the challenges I’ll face as a mother regarding maintaining that. & is very keen to help me. 2) talking to older ppl. It seems that after a certain age ppl start caring much more abt their family.
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Unironically being in a happy stable relationship has been a great boost to my professional life. I suspect we emphasise too little the role that getting a good partner has in the life of women (for both career and personal reasons).
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It's really insane how much more I get out of reading stuff than listening to it. I switched from listening to a podcast to reading its transcript and BOOM! I absorbed everything. Is there a name for this? Bcuz I often don't get what ppl say irl, so it's generalised.
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I wrote a blog post about somatic evolution, a new field with exciting implications that I am working in! I focused on its implications for disease, particulary ageing. Summary in thread below:.
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My very offline bf : . “Have you heard that Barbie and Oppenheimer were launched on the same day?”. Adorable!!!!.
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This website has become intensely dumb. I think deboosting external links has helped achieve this, because it disincentives ppl from sharing any more long form stuff.
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I see academics have learned the right lessons from this 🥴🥴🥴 self-satisfied dunking on the plebs is gonna work this time, trust me bro.
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Safetyism is the biggest enemy my generation has to battle. The dangers are immense: from depressed teens to stagnant innovation landscape. Courage & risk-taking are the most underrated values of our times.
Safetyism is strangling progress. Chat I had with a brilliant scientist today (postdoc):. “I feel like I’m no longer doing science. My job has become shuffling around ethics and compliance documents. It’s strangling our science. I am depressed. It’s like they’re trying to stop us.
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SBF studied Physics not CS & this is misleading. Quant finance is absolutely the top place for Physics/Maths ppl to go if they don’t wanna do academia. Being a programmer in finance is less prestigious indeed bcs ur not at the action center! But SBF was a physicist!.
I went to MIT & studied CS, one year under SBF. When he graduated in 2014, the place where all the top tier engineers went was Palantir. If you couldn't pass that interview, then it was Dropbox/FB etc. And the third-tier was quant/finance, ie Jane Street. SBF was tier-3 bad eng.
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I am interested in the phenomenon through which smart ppl are blatantly wrong. Balaji is obviously smart. 3 ideas:.1) he’s lying for money .2) he’s memed himself into insane ideas due to audience capture .3) you don’t need to understand the world broadly to be good at one thing.
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Even accomplished ppl change their priorities. Seeing old ppl dote on their families so much really changed my perspective and made me realise my priorities might shift.
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Tucker Carlson missed his chance to film himself in a Russian prison and marvel at the fact that you can take walks there
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Poast ur favourite moral innovation. Mine is presumption of innocence. Truly going against human nature and our impulse to jump to conclusions regarding guilt.
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Brits love being like “yeah I am middle class” and then you find out their parents own a castle.
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A lot of ppl have been asking for a skincare routine. As a biochemist I have researched this and I think you only need 4 things (in order of importance): sunscreen SPF 50, retinol (one that has retinaldehyde), moisturising cream & exfoliant. Maybe vitamin C. Products 👇.
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A guy on LessWrong wrote a 24 mins post about something that does NOT exist (diamondoid bacteria) & is just a product of Eliezer's imagination. People laugh about that girl whose dissertation focuses on Marxist fluxes of metabolic energy, but what is this?
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If I learned anything in grad school, it's that NO method can replace STARING at your raw data. This is literally a slide from my presentations. You need to get intimate with your data, know its ins & outs, become one with your data. Do it until you the lines between human and
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Non-Bio ppl sometimes ask me how to get up to speed with Biology. Most recently, @PradyuPrasad. These ppl tend to be CS/Maths oriented. Their most common complaint is: “I find Biology interesting but gave up on learning it because it is so memorisation based.”. Thread:.
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Ok. Real question. Has someone laid out a step-by-step explanation of a scenario where AI would kill us all? Like what exactly would happen?.
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People greatly overestimate how much this “social power” translates into any actual power for women. I’ve said this before and I’ll say it again: being hit on at networking events is off-putting & it’s often harder to get into the networking circles that would actually give you.
"Young women often have a lot of social power, whereas, except for the fortunate few—the born rich, the strikingly handsome, the 6-foot-3—young men have none. Socially speaking, young men are shit"
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Something I wish more people understood is how much scientific progress is slowed down for banal bureaucratic reasons. For example, I've had projects delayed for > half a year due to a need to redo ethics forms for working with human tissues, despite nothing material changing in.
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@MiriVinni Why is it bad that ppl go to bed early seems healthy . Presumably they also wake up early.
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Among reasonably smart people, the main differentiator is not raw intelligence, but interest in a topic. Maybe this does not hold true for pure maths, but for most topics it does.
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Very excited to have been awarded an Emergent Ventures fellowship ❤️🚀🎉
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If someone has a wife or a gf, I automatically consider that it's impossible they would be hitting on me. But it turns out it's not.
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