We are pleased to share our paper "Structures and mechanisms of U6 snRNA m6A modification by METTL16” Nature Communications https://t.co/FTYxDJm3f4

New online! tRNA as an assembly chaperone for a macromolecular transcription-processing complex https://t.co/15YPdu5qx7

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators. https://t.co/PTMoqQqwcU

[プレスリリース] 正確なmRNAスプライシングを制御するU6 snRNAのm6A修飾の分子機構を解明――スプライシング異常が原因の疾患理解に貢献―――新領域創成科学研究科 https://t.co/EaUsC1ilT4

RFdiffusion2 is now live! https://t.co/H5bsYd0YuA You can now design proteins, and in particular enzymes from just partially defined amino acid side chains, and without defining their sequence position or order! Great job @r_krishna3 @woodyahern @dougtischer and everyone else!

正確なmRNAスプライシングを制御するU6 snRNAのm6A修飾の分子機構を解明 ――スプライシング異常が原因の疾患理解に貢献―― - 東京大学大学院 新領域創成科学研究科

Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism: Cell

The most radically recoded genome yet! Syn57 is E Coli with only 57 codons, freeing space to encode up to 4 non-canonical amino acids. That, combined with its virus resistance, will make it an incredible tool for biomanufacturing. From the Chin Lab in @ScienceMagazine

🦠 Launching a bimonthly digest on RNA modifications and related topics in bacteria!🤩 First issue: Summer 2025. Shared here + by email, future ones will be quicker reads! 😅 #rnamodifications #bacteria #ribosome Subscribe and share if you are interested!

Featured on the cover of @ScienceMagazine, BioEmu @MSFTResearch, a deep learning system that rapidly generates diverse protein conformations for accurate insights into protein function. Illustration: N. Burgess/Science; Data: S. Lewis et al., https://t.co/V0fRBX4EXc.

Seminars by Dr. Dominique Fourmy and Dr. Satoko Yoshizawa (CNRS, ENS Paris-Saclay, Université Paris-Saclay) on new antibiotic susceptibility tests and innovative antimicrobial strategies. Really enjoyed them — fascinating work!

We are excited to share our latest research on Q-modification in precursor-tRNAs, which just got published in @NatureComms. This was an very exciting and fruitful collaboration with @francescatuorto in Heidelberg. https://t.co/73krcQRqwV

A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function:

Had a great scientific time at RNA Tokyo @ IQB UTokyo with Prof. Phillip Zamore and RNA PIs from the Tokyo area. Big thanks to Prof. Yuki Tomari for organizing! Great discussions—and a fun evening at Hantei after the seminar.

Our study where we develop EvoBind2: Design of linear and cyclic peptide binders from protein sequence information is now published! https://t.co/WPjPaWmTuT

Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale. https://t.co/WwKjj5B0eb

The eukaryotic tRNA chaperone La impacts tRNA modification levels (queuosine and others). Interesting because in procaryotes, tRNA modif enzymes themselves are thought to be chaperones. In both cases, there seems to be a link between modif and chaperones.

We attended the 26th Annual meeting of RNA society of Japan in Sendai. Wondetful meeting as always and thank you organizers! A phD student and a postdoc from my lab presented their research.

Mammalian tRNA acetylation determines translation efficiency and tRNA quality control

Thank you Prof. Rujuan Liu for hosting and inviting me to the seminar at SLST, ShanghaiTech. It was a fruitful and enjoyable visit — great to meet and discuss with faculties and students!