Patrick Rodrigues
@PatFernRod
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Postdoctoral Research Fellow | @TheColonnaLab | Washington University in St. Louis
St Louis, MO
Joined May 2021
RT @FGinhoux: Happy to share our latest paper on DC ontogeny! Congratulations to the team and to Dr Zhaoyuan Liu fr….
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RT @tmamuladze: I'm excited to share our new study published in Cell. This work uncovers a critical role for dural mast cells in shaping c….
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RT @DuSiling: 🧵1/.Excited to share my first publication from the @ColonnaLab in @NatImmunol! We investigated how mutations in the human CSF….
nature.com
Nature Immunology - Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia is a neurodegenerative disorder caused by pathogenic CSF1R mutations. Here the authors find that...
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RT @TheColonnaLab: Our new study by @DuSiling reveals how CSF1R mutations in adult-onset leukoencephalopathy with axonal spheroids and pigm….
nature.com
Nature Immunology - Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia is a neurodegenerative disorder caused by pathogenic CSF1R mutations. Here the authors find that...
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RT @TheColonnaLab: Congrats to @KedmiRanit’s group! RORγt⁺ APCs prime food-specific pTregs and induce oral tolerance. Infection or food poi….
nature.com
Nature - Immune tolerance to dietary antigens is mediated by a circuit of dedicated antigen-presenting cells and T cells, ensuring protective effector responses without compromising the...
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RT @TheColonnaLab: Big shoutout to Brown’s group: IRF8-dependent TC are essential for inducing food-specific pTregs & establishing oral tol….
science.org
In the intestine, peripherally induced regulatory T (pTreg) cells play an essential role in suppressing inflammatory responses to food proteins. However, the identity of the antigen-presenting cells...
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RT @davidrliu: In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, stud….
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RT @klechevskyLab: Early bird Dendritic cell, Myeloid cell enthusiastic! hurry up Submit your abstract and register soon! poster presentat….
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RT @maxim_artyomov: latest from our lab: .ITACONATE MECHANISM SOLVED!!. Tom Paulenda @tompaulenda solved molecular mechanism of immunoregul….
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RT @jonykipnis: Super important work from our colleague and friend, Marco Colonna @TheColonnaLab|| Rorγt-positive dendritic cells are requi….
cell.com
Deleting a regulatory element in the Rorc gene depletes RORγt+ dendritic cells from the intestine in mice, leading to a reduction of regulatory T cells and impaired oral tolerance to antigens. This...
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RT @LabWaggoner: RORγt+ DCs are key to maintaining intestinal immune balance and preventing inappropriate immune responses to food antigens….
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RT @TheColonnaLab: Excited to share that our work by @PatFernRod and @TongWu99 is published in Cell: RORγt+ DCs are required to induce oral….
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RT @YosukeKumamoto: Excited to see this finally out!! We found IL-2 made by CD301b+ DCs critical for the Th2 fate decision of CD4T cells an….
nature.com
Nature Communications - A subset of migratory type 2 conventional dendritic cells marked by CD301b expression (CD301b+DC), are required specifically for the development of Th2 cells. Here authors...
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RT @BelkaidLab: Happy to share our recent work led by postdoc @DanCorral showing that the maternal adapative immune system promotes optimal….
cell.com
Mammary intraepithelial lymphocytes enhance mammary gland differentiation during pregnancy, thereby promoting offspring fitness.
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RT @ShoutangW: Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control ….
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RT @zefachi: Excited to share that our work is featured on the cover of the latest issue of Cell Host & Microbe! Check it out! @TheColonnaL….
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RT @TheColonnaLab: Our new paper in Cell Host & Microbe:.Low-fiber diets worsen C. difficile infection by increasing epithelial MHC-II and….
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RT @CicaCanesso: I am excited to share our study showing how the immune system strikes a delicate balance between tolerating food and defen….
science.org
The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal...
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RT @TheColonnaLab: Our work by Fachi et al. @zefachi is out in PNAS! We show how NKp46+ ILC3s boost early gut defense against C. difficile….
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RT @simonyona: ✨Human dendritic cells (DC)✨ using stable isotope labelling in healthy volunteers, we define the circulating lifespan of cDC….
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