Kodi Ravichandran
@kodiravi
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Our team (@WashU and @VIB/UGent) focuses on phagocytosis of apoptotic cells, its elegant complexity, and relevance to homeostasis/disease
St. Louis and Ghent, Belgium
Joined November 2012
Huge thanks to the ECDO Board for this selection and recognizing the works from our group! I am truly honored! Thank you.
We are delighted to announce that the 2025 ECDO Honorary Lecture will be awarded to Kodi Ravichandran for his extraordinary discoveries in the field of Efferocytosis. The Award ceremony will take place during the ECDO 2025 Conference in Berlin (7-10 Oct, 2025).
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We are delighted to announce that the 2025 ECDO Honorary Lecture will be awarded to Kodi Ravichandran for his extraordinary discoveries in the field of Efferocytosis. The Award ceremony will take place during the ECDO 2025 Conference in Berlin (7-10 Oct, 2025).
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A beautiful story from the @Andersonbuglab!! @Ravi_Research Metabolite-based inter-kingdom communication controls intestinal tissue recovery following chemotherapeutic injury: Cell Host & Microbe
cell.com
Anderson et al. demonstrate that host cell death drives dysbiosis and disease following chemotherapy. Intestinal epithelial cell apoptosis and the release of soluble metabolites promote Enterobacte...
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Conversation between host &gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy Preview of @Andersonbuglab @kodiravi work showing chemotherapy-induced apoptosis drives dysbiosis &transcriptional rewiring,delaying intestinal recovery https://t.co/bg4VQRsyab
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Congratulations to CJ Anderson, many members of our group at VIB/Ghent University, and CJ's new team at Univ of Edinburgh - remarkable body of work and exciting discoveries!
September Featured Article: Interkingdom communication controls recovery following chemotherapeutic injury @Andersonbuglab @kodiravi
https://t.co/XaEl4IB4Hk
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Huge Congratulations to Parul Mehrotra @MehrotraPa, Sophia Maschalidi @Maschalidi, and many coauthors from our group, plus key collaborators (Mo Lamkanfi, Esther Hoste, Umang Jain) in dissecting the hidden tissue repair roles of the pyroptotic secretome!! https://t.co/GvhoS9ziRl
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Huge Congratulations to Parul Mehrotra @MehrotraPa, Sophia Maschalidi @Maschalidi, and many coauthors from our group, plus key collaborators (Mo Lamkanfi, Esther Hoste, Umang Jain) in dissecting the hidden tissue repair roles of the pyroptotic secretome!!
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Pyroptotic cells release oxylipins and metabolites that act as mediators of tissue repair! 🔥🔥🔥 Check out our recent work in @Nature! Thanks to all coauthors @maschalidi and the incredible @Ravi_Research @kodiravi labs! https://t.co/11oLpqqMSo
nature.com
Nature - Defining the composition of the secretome of pyroptotic macrophages reveals the involvement of the component factors in wound healing.
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Thrilled to share our work with @MehrotraPa and @Ravi_Research @kodiravi identifying oxylipins and metabolites from pyroptotic cells as promoters of tissue repair. Out today in @Nature Huge thanks to all coauthors and collaborators! https://t.co/eVozPyO0Zd
nature.com
Nature - Defining the composition of the secretome of pyroptotic macrophages reveals the involvement of the component factors in wound healing.
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Huge congratulations to Turan Tufan for defining how macrophages use pause/release to rapidly (within min) modify their gene and protein expression during efferocytosis to ingest successive corpses! Thanks to many coauthors who helped us along!
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Last year, while applying to ophthalmology, I took an elective in endocrinology. My attending said, "The eye is not an endocrine organ." I replied, "As far as we know." WELL. Now we have evidence of endocrine (OK, paracrine) signaling with endogenous insulin in the retina! 🤯
Congratulations to J. Iker Etchegaray (and many co-authors) for detailing an unexpected role for phagocytosis by the RPE in inducing a local insulin source in the eye, how it is distinct from systemic insulin, and its impact on retinal physiology.
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Congratulations to J. Iker Etchegaray (and many co-authors) for detailing an unexpected role for phagocytosis by the RPE in inducing a local insulin source in the eye, how it is distinct from systemic insulin, and its impact on retinal physiology.
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Out today from The Perry Lab @Cell_Metabolism
https://t.co/90Fmqv1UBG. Sincere thanks to the lab, collabs, & the editors at CM and @CellCellPress who really worked hard to get this paper over the finish line (more below). The tweetorial can be found here
cell.com
Tissues pose distinct challenges that macrophages must overcome, including limited nutrient availability (glucose, oxygen), to perform essential functions such as apoptotic cell clearance (efferocy...
The Perry Lab is really excited to share our latest story "Novel adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments"! https://t.co/Bw2mPE31YO Explainer (and videos) below 👇
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CHEF Kodi did it again!! Harnessing the power of ELMO to increase the appetite of cells in living organisms and dramatically improve #resolution_of_inflammation l Future therapy?! A-ma-zing!! Congrats team 🔥 @kodiravi
@CellCellPress
https://t.co/p0lBaPeg9d
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Huge congratulations to Sho Morioka, other lab members, and collaborators on a new way to boost efferocytosis and dampen inflammation in disease models
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Thank you, Art. I will add that this meeting also covers other modalities of cell death as well as tissue regeneration and repair. Thanks.
If you want to know all things related to efferocytosis - go to this meeting!!! @EMBO @kodiravi #efferocytosis #phagocyotosisofdeadcells #hungryhungrymacrophages
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Join us for the EMBO meeting with an exciting lineup of topics and speakers in the lovely city of Ghent, Belgium, from Sep 12-15, 2022 . Due to relaxation of COVID rules, we have ~20 more additional spots. Please register soon! Kindly retweet - thanks!
meetings.embo.org
Everyday, we turnover >100 billion cells in our bodies. The excess, used, or damaged cells that turnover usually die and are then recognized and removed by nearby or recruited phagocytes. Phagocyt…
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Congratulations to @Mehrotra_Pa on two counts. First, her publication today in Nature Rev Drug Discovery ( https://t.co/pcnbPDcSnj) on "Drugging the efferocytosis process". Second, for securing an Asst Prof position to start her lab in IIT, New Delhi - so well deserved!
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