Roni Nowarski
@NowarskiLab
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Studying how interactions between tissue and immune cells shape immunity and inflammation @harvardmed and @BrighamWomens
Joined May 2023
RT @ASIPath: Speakers from @BrighamWomens/@harvardmed, @cwru, @cinvestav will provide insights into various aspects of innate and adoptive….
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Imagine there's no treatment.It's easy if you see.Nothing to fight your cancer.Or autoimmunity.Imagine all the research.Ceasing to exist.Woo-hoo hoooo.
Can you believe that universities with tens of billions in endowments were siphoning off 60% of research award money for “overhead”? . What a ripoff!.
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A terrific synopsis of bistability in innate immune signaling by Jayajit Das and Giuseppe Giuliani, previewing our paper on macrophage tolerogenic memory published today @Immunity
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RT @ButovskyLab: Our new work published today @NatrureMedicine The work led by Neta Rosenzweig (@NetaRose11) and Ki….
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RT @jkagan1: Why are there so few drugs that target innate immune signaling pathways? Maybe bc we know so little about the natural protein….
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RT @BrighamResearch: New research from @NowarskiLab uncovers a 'switch' in the gut that can provide protection against harmful intestinal i….
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RT @jkagan1: @ImmunityCP A must read for anyone interested in how innate immune signals impact intestinal inflammation.
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Incredibly proud of Tyler Mertens, Aditya Misra @amisra96, Peng Xiao and the team for figuring it out! Big thanks to @FlavellLab, @m_hemberg, @KanarekNaama and @AnaAndersonlab! .Read more here @ImmunityCP:
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This tolerogenic state is maintained and reinforced in macrophages by a bistable circuit driven by cGAS-STING activation, and by an intercellular positive feedback loop sustaining epithelial IL-18 and macrophage cGAMP secretion.
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Very excited to share our paper showing that IL-18 activation of the salt transporter NCC programs durable immune tolerance in the gut! We found that NCC induces a metabolic switch in macrophages that stabilizes fatty acid oxidation and prevents glycolytic reprogramming ⬇️
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Thrilled to have our work mapping tissue remodeling in intestinal inflammation online! An amazing collaboration between @SivanathanKisha and Paolo and Jeff in the @MoffittLab probing the diversity and origin of #inflammation associated #fibroblasts.
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RT @gadishamia: If you don't live in Israel or consume Israeli media, you don't know who Yair Golan is. He is a 61-year-old retired Major G….
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Taking a break from the Harvard Immunology retreat for a Colgate audition
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So proud of Aditya Misra @amisra96 for being selected as a @MathWorks Engineering Fellow in recognition of "outstanding academic record, exceptional background, and promising future". Keep at it Rockstar!.
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RT @dana_peer: The most beautiful spatial paper I have seen, a notch (or two) above all the rest. Congratulations to the team.
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Excited to announce the results of an exciting collaboration with Jeff Moffitt and @MoffittLab at @harvardmed, where we charted the cellular organization of the #gut and show how #inflammation shapes fibroblast trajectories and tissue remodeling! .
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