Naama Kanarek
@KanarekNaama
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Metabolic adaptability is magical. A researcher, a mentor, a teacher. Harvard Medical School Professor @Boston Children’s Hospital. opinions are my own.
Boston, MA
Joined June 2018
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If you don't STRONGLY condemn Hamas and what they did on Saturday - I don't want to work with you. On anything. Ever. This is a rational and professional decision - I simply don't trust your judgment
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I am happy and excited to start my own lab next week
@BostonChildrens
, Pathology Department. Big thank you to
@DMSabatini
and the Sabatini lab for making me the scientist I am. I will miss you!
..... off to study my big love:
#Folate_metabolism
:)
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Looking for some light reading for the long days at home?
Check out our
@nature
review with
@DMSabatini
and
@KanarekLab
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So we
@KanarekLab
think that we found the molecular etiology for anemia caused by folate deprivation. Kudos to
@amaynard_
who led the work and everyone who helped. Check it out.
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The
@KanarekLab
is celebrating:
1. 1/2 birthday (6 months already!)
2. A grant (thanks
@CHoodFoundation
3. Acceptance of our review with
@DMSabatini
to
@nature
(wait for it..)
Good times!
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Kanarek Lab | Folate Metabolism | Boston Children's Hospital
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This is shaking the core of my existence and life in Boston and in the US academia
This is the reality that MIT President wants to hide. A letter from Israeli & Jewish MIT students:
To all students at MIT,
Today, Jewish and Israeli MIT students were physically prevented from attending class by a hostile group of pro-Hamas and anti-Israel MIT students that
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Thank you Smith Family Awards Program for Excellence in Biomedical Research via
@hriaction
for supporting our research of the cellular response to folate deprivation. We are excited to get the work done!
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While completely distracted by the war in Israel, I still want to let people know that
#AmazingBory
made it easy for others to detect redox metabolites in mammalian cells and tissues by LC-MS
@KanarekLab
Check it out
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Our work is now published
Work from
@DMSabatini
at Whitehead Institute to uncover ways of improving methotrexate chemotherapy, reveals potential role for histidine supplementation in increasing sensitivity of cancer cells to drug. .
@MITBiology
@MITScience
@kochinstitute
@HHMINews
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Check this out! Our new collaborative work with
@LehtinenLab
. See the🧵
ChP-CSF targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy.🧠
Excited to have this collaborative investigation with Boryana from
@kanareklab
@KanarekNaama
out in
@Neurocellpress
, led in our lab by
@JangAhram
. [1/3]
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@KanarekLab
at Red Carpet Event celebrating the grand premiere of our homemade videos (aka metabolomics tutorials). See here:
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Our
@jbiolchem
review on the regulation of 1C metabolism is now out. Check it out (or at least the figures :) )
@KanarekLab
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The
@KanarekLab
is excited and grateful for
@CureCancerNow
for their decision to fund our leukemia research
@BostonChildrens
.
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Finally!
@KanarekLab
+
@HogstromJenny
and
@tarumurmur
can celebrate in person with 4 good reasons [1] collaborative grant with
@tarumurmur
[2] Bory's promotion to HMS instructor and [3] a
@BostonChildrens
grant with
@LehtinenLab
and
@HannoSteen
[4] its spring
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@OdedRechavi
My personal experience was nothing but positive. I am Harvard faculty, known for being an Israeli and I was supported,hugged, and listened to by all the people around me. From faculty, trainees and administrators.
Don’t live in Twitter. It sucks. Our world is a better place.
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The
@KanarekLab
is looking for an RA to join our team and work with amazing Bory.
#metabolomics
Please RT.
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Check out our Preview by
@amaynard_
in
@Cell_Metabolism
In reference to the latest Rabinowitz paper regarding serine-derived NADH production .
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Thank you BSF
@usisraelbsf
for funding our collaborative work with the Nachmani lab
@DaphnaNachmani
in Jerusalem, Israel. We are really excited to dive with them into their world of RNA biology.
Really, but really, outside my comfort zone!
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today is the holocaust memorial day. This 1941 photo (was shared today during a ceremony by the Israeli president) made me stop everything and think about the many mothers that held their son's hand just before they were killed. What did they say? What could they possibly say??
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I agree with Hidde!! Read here: End the wasteful tyranny of reviewer experiments | Nature
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This story is about us.... Fund Helps Parents Be with Their Hospitalized Child
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Proud of my students Riley, Nancy, Amy and Alan for presenting their work today at HMS pathology retreat, and happy for Amy and Alan for winning best posters. A good day for the
@KanarekLab
:)
#folaterocks
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Thank you
@CHoodFoundation
!!
The Hood Foundation is honored to announce our most recent Child Health & Major Grant Award Recipients!
Sincere thanks to all of the highly qualified investigators who submitted proposals, as well as our amazing Scientific Reviewers.
Visit for details.
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Very proud of my student Amy Yu for receiving the NSF GRFP doctoral award. Very well deserved and making me so very happy :)
GO AMY!!!
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Thank you
@nada_kalaany
for coming! It was fun to have you there :)
And it’s a great launch 🚀 Today with
@KanarekNaama
on Intro to
#CancerMetabolism
👏. In-person engaging discussions + snacks 🍪 ☕️ 🍎!
Join us next week for another awesome lecture on Oncogenic
#nutrient
sensing with
@alex_toker
@LandryCancerBio
! 🤩
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Did you ever wonder about mitochondrial nutrient sensing? Well, then read this! I think they found a mitochondrial nucleotide sensing mechanism. mitoTOR? miTOR? Except of course it’s not “target of rapa” so maybe we need a new name… super cool either way!
Thanks to
@KanarekNaama
and group for the help and collaboration! See also
@langer_lab
,
@NGrotehans
,
@tommacvicar
recent preprint for more on NME6.
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Long thread. Stay with me.
I heard about teachers who chose to deal with the recent Hamas atrocities by talking with the kids about the Israeli-Palestinian conflict. This is wrong and hurts both the Palestinian legitimate struggle AND the innocent Israeli victims. See more...
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We got quite hungry after all that great science today at the Boire-Kanarek retreat
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Our very own Dr. Maynard! Congratulations
@amaynard_
for successfully defending your thesis, and for a brilliant talk. We are so very proud :)
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SO so happy to be part of this list. Thank you
@adrienne_boire
for spearheading this, and excited to get this project going. Will be fun!
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Checkout this creative work by
@ptrtsvetkov
- published in
@ScienceMagazine
- Copper induces cell death
#cuproptosis
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Proud that the
@KanarekLab
is part of this:
@BostonChildrens
Hospital will participate in newly launched
#IMPACC
#COVID
-19 study. The study will examine immune responses of people hospitalized with COVID-19.
@levy_o
of
@PrecVaccines
will lead the study
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@KanarekLab
is bubble-tea-celebrating with Nancy - who just had her PQE! Congratulations Nancy :)
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Celebrating Hanukkah and metabolism with Sufganiot. Although Sufganiot is mostly fatty acids metabolism and we don’t really study that….
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Checkout our new website
@KanarekLab
@BostonChildrens
Kanarek Lab | Folate Metabolism | Boston Children's Hospital
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@Manning_BD
@Gerta_Hoxhaj
@bensahralab
#nutrientsensing
The way I see it- NME6 is a mitochondrial nucleotide sensor. What do you think?
#mitomTOR
?
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Can’t wait to run some samples. Thank you
#pathology_BCH
for this amazing opportunity
KanarekLab had a BIG day: unpacking our QEs, before and after. So exciting to see and hear first signs of life!
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Lab hike! More like a lab stroll actually.
Thank you Chiarle lab guests for joining :)
@KanarekLab
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Excited to give a talk tonight (literally tonight, btw, not “this evening” or “afternoon”) at the
#cshlnutrient
. Thank you
@DMSabatini
@BrunetLab
@trotmanlab
and
#NoTwitterNav
for organizing and giving me the opportunity to speak.
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This wa fun. Looking forward for day 2
Thank you
@LandryCancerBio
Day one of our nanocourse: Toxicity of Cancer Therapy - Lessons from Metabolomics with
@KanarekNaama
and
@LehtinenLab
!
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The amazing people in my lab celebrating the beginning of the celebrations season. Thank you for hosting
@tarumurmur
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This work was possible thanks to the support of the
@Revson_Fdn
and their Women in Science award!
Thank you for providing the support when I most needed it!
#WomenInScience
Weizmann Alumni Fellow Naama Kanarek
@KanarekNaama
is doing important research on cancer chemotherapy! Be sure to read her article in
@nature
!
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@ribosaur
I think increasing the availability of personal mentorship to young female scientists (PhD level) by more senior female scientists might help, motivate, guide and inspire these bright young females and will encourage them to stick around.
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If you ever ask yourself what’s happening in you brain when you’re asleep… check this out!
One of our favorite projects :)
Such a cool integration of tools and creative thinking by Ryan Fame!
Metabolism in the ChP was also vastly different between day and night. In collaboration with Bory Petrova and
@KanarekNaama
we identified that more metabolites are in the oxidized state at night. CSF metabolites also change with Thyroid Hormone ⬆️ in CSF at night.[6/9]
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Toy Drive by
@SSDSBoston
for . When an amazing community decides to help hospitalized children at
@mghfc
, wonderful things happen :)
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Caroline and her team at the
@WhiteheadInst
care about the users’ projects like they were their own. Here’s to the best metabolomics core!
When a researcher approaches the Metabolite Profiling Core about a project, step one is talking through the best approach, says Caroline Lewis: “They come to us & we have a discussion about what question they really want to answer.”
#ThankYouCoreFacilities
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Can’t wait for the great things
@MariaMMihaylova
will do with these funds!!
Congratulations:)
#OSUWIMSCongratulates
Dr.
@MariaMMihaylova
, assistant professor of Biological Chemistry and Pharmacology, who was selected for the 2021 NIH Director’s New Innovator Award!
#OhioStateWIMS
#OSUWexMed
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Tomorrow we will start our joint retreat with the Boire Lab
@MSKCancerCenter
, our STARR collaborators and good friends (even though they are from New York… 🤷🏽♀️…nobody’s perfect)
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Wonderful work
@ChristofkLab
! Check out our new preprint with (somewhat complementary, albeit different maternal pathology) embryonic CSF metabolomics: bioRxiv 2023.12.06.570507; doi:
So excited to share our latest research on fetal metabolism in diabetic pregnancy, outstanding work by Cesar Perez Ramirez in collaboration with the labs of Jun Park and Atsushi Nakano at UCLA
-HRC
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...so many people to thank for this!
#Pathology_BCH
@BostonChildrens
and of course AMAZING Bory :)
day 2 and 3: finished setting up the basics. Thanks to LC-MS specialists from
@thermofisher
for all the help
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Congratulations Kim lab!
Today I celebrate the publication of the research paper I have worked hard to develop for the past 4 years. Next up, thesis defense- PhD here I come! Most importantly: I could not have done this without my family, friends, and lab mates. Congratulations, Kim Lab! 🎉🎉🎉
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Amazing help for the community! Thank you 🙏
If you don't get it, you don't get it
Download our (updated) massive database of POSTDOC fellowships.
We list 373 fellowships w/ description, $ amount, deadline, and eligibility criteria (e.g. citizenship).
HERE:
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You can help parents of hospitalized children
@mghfc
that face additional hardship due to COVID by sending comfort packages
Will you not do it?
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the holidays are here. everyone should have their loved ones with them. especially those who are ill, and scared, and away from home. especially if they are kids. help us bring parents to their hospitalized children's bedside
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This will be fascinating
Listen to
@kristinknouse
discuss how understanding the liver’s regenerative ability could show how to confer that ability on other organs to repair injury & disease. May 8, 6-7 PM
@WhiteheadInst
. Part of our
#SpringIntoScience
lecture series. Register:
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Beautiful work by the Kim lab!
Online now! A micronutrient with major effects on cancer cell viability
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Congratulations
@DMSabatini
!!
Congrats to
@DMSabatini
for earning the 2019 Louisa Gross Horwitz Prize from
@ColumbiaMed
! He is 1 of 3 researchers to receive this accolade for their seminal contributions to the role of the PI3K pathway in physiology and oncogenesis:
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Really excited about this webinar series! Thank you for including me and can’t wait to listen to the talks :)
@HaigisLab
Confirmed speakers also include
@Caroline_Bartma
@nada_kalaany
Celeste Simon
@LyssiotisLab
#NoTwitterNav
@DavidFinlayTCD
@laoneill111
@FilippoVeglia81
@andMORand
@OlivierFeron
@KanarekNaama
Andrea Viale
@WellenLab
@FrezzaLab
@rushika_perera
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Go Roberto!!
5 years since starting his lab the big day is here :
@RobertoZoncu
tenure talk
@UCBerkeley
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Bring Naama home. And everyone else. How can we live our lives while these kids are abducted? My heart is broken. My thoughts are with them
Help us bring home Naama Levy and all the hostages from the Hamas terrorist attack NOW
Naama Levy, peace-seeking, terrified young girl, handcuffed and with bloody clothes, being pushed into a 4x4 vehicle by maniacal terrorists
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An important interview with a smart person
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We need more of these stuffed-animals/blankets to offer some
#comfortatthebedside
to babies at
@mghfc
Please help by clicking here:
or read more:
or:
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This is pure goodness! Thank you
We just updated on database of POSTDOC fellowships in ONCOLOGY/CANCER RESEARCH.
We include description (link), deadline, amount, and eligibility.
50 fellowships.
Download it for free here:
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Great commentary by my brilliant student
@amaynard_
, supported by
@LandryCancerBio
Hey everyone! My name is Adam Maynard. I am a 3rd year
@BBS_Harvard
PhD Candidate in the
@KanarekLab
! Today I will be taking over the Landry twitter account to share some of my thoughts and experiences from grad school. I will be updating this thread throughout the day. (1/n)
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Just an example: We helped the mother of a baby who has spent most of his nearly 1 year of life in the hospital to be with her baby by paying for gas. Help us help others like her
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New paper!
Beautiful work by Nick Kramer and Gyan Prakash from the
@fiddle
Sterling lab
🎉Our paper "Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression" is now online! 🎉
Summary ⬇️but the published manuscript is greatly expanded! Congratulations to Nick Kramer,
@GyPrak
thanks to
@KanarekNaama
for collab.
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Thank you!
So excited it’s out!
Just out: A great review article by
@KanarekNaama
, Boryana Petrova and
@DMSabatini
on dietary modifications for enhanced cancer therapy👇
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Can’t agree more with
@DMSabatini
Our lab lacking everyone non-USA born(middle). Bottom also removes those with foreign-born parents, which includes me. Diversity represented: India, Netherlands, Austria, Germany, Ethiopia, Russia, Haiti, Poland, Brazil, Hong Kong, China, Philippines, Ukraine, Colombia, England!
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@PetrovADmitri
@Stanford
I’m deeply disappointed by the meek response by American academia leadership all around. The fear to say anything too strong, even in the face of pure evil, is not being progressive, it’s being wrong.
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Can’t say enough about
@h_r_keys
‘s professionalism, rigor and ability to help the novice screener!
In the Functional Genomics Platform
@WhiteheadInst
, Heather Keys helps researchers adapt CRISPR screens to new types of research questions. “It opens up a lot of doors for different types of science,” she says.
#ThankYouCoreFacilities
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Can you imagine a child spending days and nights alone in the hospital without the presence of a parent to support, hug and help? You can do something about it!
#GivingTuesday2020
@mghfc
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I was a guest in this lab during my PhD and my visit changed the way I think about science, and motivated me to make research my life. If you consider a postdoc - take a look here
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It is very satisfying to realize how we are aligned in our interpretation of the next frontier of the
#cancer_metabolism
field
@LocasaleLab
@LabVousden
@DMSabatini
@KanarekLab
Related recent reviews from
@LabVousden
and
@DMSabatini
@KanarekNaama
and colleagues
@Cancer_Cell
and
@nature
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Hello
#sciencetwitter
, the
@KanarekLab
are looking to collaborate with a developer (node.js) on some advanced mass-spec analysis tools. We have the tool, but we need the developer.... Please send to people who might be interested and please RT.
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toy drive 2021
Donate this month and your donation will be matched (up to $10,000)
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Join us! Will be fun
📢 We have an exciting new nanocourse in May!
Cancer Metabolism: The Metabolomics Perspective
Keynote speakers
@KanarekNaama
,
@alex_toker
,
@MostoslavskyLab
and
@nada_kalaany
!
More info & registration
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Come join our nanocourse!
@LehtinenLab
@LorenWalensky
and with
@LandryCancerBio
at
@harvardmed
and
@BostonChildrens
New Harvard nanocourse covering CSF metabolite profiling in the context of chemotherapy, led by Naama
@KanarekNaama
, Loren
@LorenWalensky
, and myself. This March 5 & 26. Sign up below!
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Checkout this out! Another beautiful work by
@ptrtsvetkov
Our Pre-print is out, showing that FDX1 is an essential upstream regulator of protein lipoylation in human cells. This is mediated through direct binding of FDX1 to the lipoylating enzyme LIAS and not through Fe-S cluster regulation.
@BroadCancer
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This is a fantastic work bridging cell cycle and nutrient sensing through allosteric regulation of a key enzyme in the pyrimidine synthesis pathway. So simple. Makes SO MUCH sense. Congratulations to the team.
I am pleased to share new work out in
@NatMetabolism
, the Magnum Opus of former PhD student Josh Shin! Josh wanted to understand precisely how cancer cells regulate metabolism to meet the demands of each phase of the cell cycle
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Congratulations! Makes me so happy to see so many familiar faces of scientists I look up to both personally and scientifically.
Please join us in celebrating the new Freeman Hrabowski Scholars, who will help us build a strong foundation for the next generation of scientists!
#FHScholars
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Conclusion - what happened on Saturday was a pogrom motivated by a desire to kill Jews. Any connection between this event and the Israeli-Palestinian conflict diminishes the severity of these evil deeds and the depth of sorrow they brought but also hurts the Palestinians who
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*To explain what that means, 800 casualties in Israel are equivalent to about 28,000 casualties in the US: imagine that. In one day. Civilians. And the numbers are still rising*.
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Great news! The Pew community just got better
I am incredibly honored to be selected as a Pew-Stewart Scholar! A huge thank you to my team for their dedication and creativity, and excited for the opportunity to further explore the realm of NADPH cofactors in cancer. Congratulations to all the 2023 Pew Scholars!
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Thank you
@harvardmed
. It was really fun :)
Looking forward to hearing from Ranjith from
@eGenesisBio
, Naama
@KanarekNaama
from
@harvardmed
@BostonChildrens
and Sebastian
@LouridoLab
@MITBiology
@WhiteheadInst
starting at 4pm. Register here: .
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Thank you for the picture Izabella. Indeed a fun afternoon!
Today I,
@KanarekNaama
and
@hoy_Shen
had the pleasure to present our works on vitamins B6, B9 and B12, respectively, at
@TuftsUniversity
to celebrate Dr Jacob Selhub’s career and legacy! We are so lucky to have Jacob around, nobody knows more about vit B than him!!!
#vitaminB
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@OdedRechavi
Two daughters that went through hell just before taken to Gaza. They have a long way to recovery :(
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Please RT.
Now, with COVID-19, even more families suffer from financial instability and need our help
#GivingTuesday2020
Can you imagine a child spending days and nights alone in the hospital without the presence of a parent to support, hug and help? You can do something about it!
#GivingTuesday2020
@mghfc
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I bet postdocing with
@Gerta_Hoxhaj
will be an amazing experience
Looking for talented postdocs with training in biochemistry, molecular biology and/or cell biology! Job details are in the Nature ad:
#phdchat
#AcademicTwitter
#scicomm
#postdoc
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Bring Naama back! A peace activist, a young girl, a daughter, a human being. How can people justify abducting her as an act to free Palestine exactly? Its people like her who can seed the hope for peace between our two nations
#BringThemHomeNow
This is Naama Levy.
Naama is still in the hands of Hamas. What have they done to her?
Where is the
@unwomen
?
@unwomenchief
?
Please share - We want Naama and all of the hostages back.
#bringthemback
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Pathology Department
@BostonChildrens
is now hiring.
Come join a fantastic scientific community!
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Such a beautiful story by
@chivukula_raghu
and
@DMSabatini
Thrilled to share that our work identifying a new form of human lung disease is now published! Thanks to all involved, particularly the patients and families. Hopefully we can leverage these insights to aid in diagnosis and therapy!
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