Mazen Noureddin, MD, MHSc @NoureddinMD profile

Mazen Noureddin, MD, MHSc

@NoureddinMD

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Prof of Med, Hepatologist @Methodisthosp . Researcher, Dir Houston Research Institute. Father to 2 girls. AE @AGA_CGH

Houston, TX

Joined November 2016

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

The new AASLD guidance for #NAFLD are here! 2023 also started with pos phase 3 RCT. data. Congrats @marurinella et al #livertwitter #MedTwitter @drmoutaz @AASLDPresident @AASLDtweets @AASLDFoundation

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Mazen Noureddin, MD, MHSc

@NoureddinMD

11 days

RIP big brother! Stephen last few days were filled with what he loved most. He was writing a piece about Resmetirom use and was pushing it w his close friends throughout the weekend. He passed from natural causes on Tuesday. His legacy will continue and we will all miss him…

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

My heart and prayers go out to the people from my city #Aleppo who were hit with the earthquake. Growing up I have never imagined this city and country will go through so many tragedies 🥹. @AlkhouriNaim @NoureddinNabil #aleppo_earthquake #Syria_earthquake #Syria @cnnbrk

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Here is the new nomenclature for #nafld ! Presented at @ddw2023 ⁦ @AlkhouriNaim ⁩ ⁦⁦ @AASLDtweets ⁩ ⁦ @EASLnews ⁩ ⁦ @AGA_CGH ⁩ ⁦ @JonathanStineMD ⁩ ⁦ @nagachalasani ⁩ @AlinaAllenMD ⁩ ⁦ @marurinella ⁩ ⁦ @phil_newsome7 ⁩ #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

⁦ @AlkhouriNaim ⁩ becomes a fellow of the ⁦ @AASLDtweets ⁩ the highest honor of our society! Congrats. ⁦ @LiverArizona ⁩ ⁦ @AlinaAllenMD ⁩ ⁦ @NoureddinNabil ⁩ ⁦ @schattenbergJ ⁩ ⁦ @ebtapper ⁩ @NASH_and_coffee ⁩ #TLM22

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Life is unfair😢This is a devastating heartbreaking day to our hepatology community. Keep our friend and colleague @VinaySundaramMD in your prayers! #livertwitter @AASLDtweets @DrLiver @KowdleyMd @AlkhouriNaim @RajivJalan1 @rajVuppaLanchi @AsraniSumeet @lilydaramd @ArpanPatelMD

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 months

Hot off the Press: The Most Important MASH phase 3 RCT hopefully leading to first Drug approval for MASH is out #livertwitter

A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis | NEJM

Nonalcoholic steatohepatitis (NASH) is a progressive liver disease with no approved treatment. Resmetirom is an oral, liver-directed, thyroid hormone receptor beta–selective agonist in development ...

www.nejm.org

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

#NALFD nomenclature update. A Pic worth thousand words ⁦⁦ @AASLDtweets ⁩ ⁦ @EASLnews ⁩ #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

My parents and I have not seen my brother for 5 years. We haven’t met his first son. They were not allowed! My mom dad and all of us are full of hope today to see them soon. @JoeBiden @KamalaHarris #ban #dignity

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

💡Our New Paper in #hepatology using Machine learning to predict various stages of #NASH and #NASH fibrosis. #ML models did better than Conventional NITs including #fibroscan #livertwitter @AASLDtweets @EASLnews @LITMUS_IMI @AlkhouriNaim @schattenbergJ

Machine learning models are superior to noninvasive tests in identifying clinically significant...

ML models performed better overall than FibroScan, FIB-4, FAST, and NFS. ML could be an effective tool for identifying clinically significant liver fibrosis and cirrhosis in patients with NAFLD.

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Fatty liver is still under diagnosed and many patients present for the first time with cirrhosis 👎🏻. Screening in diabetics & overweight people should be started. International NASH day June 12. #livertwitter #NAFLD #MedTwitter @intNASHday @NAFLDSupport @GlobalLiver @NASH_AWARE

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 months

#Resmetirom is the first FDA drug to be approved for NASH/MASH patients without cirrhosis! #livertwitter it took long years but what a rewarding journey for those who were part of it! Happy for our patients. More work to be done @MadrigalPharma @AASLDtweets @HMethodistMD …

Yaron Rotman

@NASH_and_coffee

2 months

Important day for hepatology - 1st ever medication approved for #MASH #NASH ! Resmetirom approved by @US_FDA for people with MASH & fibrosis but no cirrhosis. Let's hope the promise shown in clinical trials will hold in real life outcomes. #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

In London early for #ILC2022 and Celebrating father’s day with this guy ! #LiverTwitter (Red jackets memo) @AlkhouriNaim

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

هذا هو جهاز الفايبروسكان والذي يقيم: ✨درجة دهن الكبد ✨درجة خشونة الكبد متواجد في الشرق الأوسط و البلاد العربية @drmoutaz @wedocaresaudi #طب #لطلاب_الطب #كبد #أجهزةطبية

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

🔥Breaking News: Madrigal Announces Positive Topline Results from the Pivotal Phase 3 MAESTRO-NASH Trial of Resmetirom for NASH and Liver Fibrosis. #livertwitter @AlkhouriNaim @NASH_and_coffee @AlinaAllenMD @ebtapper @novonordisk @madrigal @akerotx #GITwitter @AleksanderKrag

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

علاج التهاب الكبد B...في اميركا نسخدم إما Velmidy أو entecavir. أفضل الأول لانه لا يترافق مع طفرات فيروسية (يعني الفيروس لا يمكن ان يقاوموا). العلاج لا يجب ان يوقف اذا بدأ. البحث العلمي جاري لاستكشاف علاج يشفي تماما منه بدلا من العلاجات الحالية. @drmoutaz @wedocaresaudi

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Not doing a single thing related to work or medicine tonight. I am spending this time #girldad #MedTwitter @AlkhouriNaim @NASH_and_coffee @DrLiver @NoureddinNabil #FamilyFirst

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Honored this weekend to speak @ National #liverconnect conf in AZ and update pic w Harvey Alter ( #NobelPrize 2020 recipient) who I had the honor to work with @NIH and follow w a talk @ScrippsHealth @ their 36th Annual Liver Conf. @AlkhouriNaim @NASH_and_coffee #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Congrats to the future GI fellows who matched today including my mentees. For those who did not match, keep at it👊🏼❤️I remember when I didn’t match first time in GI, I felt it was the end of the world! I am a faculty now 🙂 #GITwitter #LiverTwitter #MatchDay2022 #gifellowship

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Liver transplantation cover ❤️ A pic worth thousand words ⁦. ⁦ @marurinella ⁩ ⁦ @AlinaAllenMD ⁩ ⁦ @Mayo_liverdoc ⁩ ⁦and many others ;) #livertwitter ⁦ @AlkhouriNaim ⁩ ⁦ @NASH_and_coffee ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

اخ في السعودية تبرع لوالده بجزء من الكبد من سنة. سألني اذا في أي ادوية لازم يمتنع عنها. الكبد عضو مميز واذا وضعت منه جزء فقط فأنه ينمو خلال ٨ اسابيع من الزراعة إلى حجم كامل تقريبا. نفس القصة تحصل مع المتبرع. الكبدان يعملان بشكل طبيعي فورا بعد الزراعة @drmoutaz @wedocaresaudi

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

#NAFLD nomenclature update! Here we are so far in our discussion!! #livertwitter ⁦ @AASLDtweets ⁩ ⁦ @EASLnews ⁩ ⁦ @AlkhouriNaim ⁩ ⁦ @NASH_and_coffee ⁩ ⁦ @schattenbergJ ⁩ ⁦ @JVLazarus ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

خبر مبشر: دواء السماغلوتيد Semaglutide أثبت في دراسة جديدة أنه يؤدي إلى نقص ٢٠٪ من الوزن عند الناصحين. أكثر دواء أثبت فعالية لمعا��جة السمنة. #السمنة #صحتك_تهمنا #البدانة @drmoutaz @sayidatynet @mohapuae

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

When your youngest sibling is in the same field you are in and attending the same #ddw2020 meeting. My fav GI fellow ⁦ @NoureddinNabil . Proud of you!⁩ @DrLoomba ⁩ ⁦ @AlkhouriNaim ⁩ ⁦ @UCSD_GI ⁩ @NASH_and_coffee ⁩ #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Good day for #NASH : Akero Press release: EFX 50mg (41%) and 28mg (39%) groups demonstrated ≥1 stage improvement in fibrosis vs the placebo rate (20%) 50mg (76%) and 28mg (47%) groups demonstrated NASH resolution w/o worsening of fibrosis, vs placebo rate (15%) #livertwitter 1/2

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

MAST score combines PDFF+MRE+AST to identifies pt with NASH and significant fibrosis (>=F2) accurately in clinical trials. We also presented data assessing longitudinal changes to Resmetirom this past @AASLDtweets #TLMDx #livertwitter @AlkhouriNaim @NASH_and_coffee @Pinnacle_TX

Journal of Hepatology

@JHepatology

2 years

🆕Article just out❕ MRI-based (MAST) score accurately identifies patients with #NASH and significant #fibrosis By @NoureddinMD & colleagues Read more here➡️ #NAFLD #FattyLiver #LiverTwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Two uncles in their 70s with COVID19. Both in the middle east & hospitals are completely full. Trying to help managing over the phone with one of them quite sick. This is the most I felt helpless, powerless and tired as a physician . #MedTwitter #COVID19

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

#NAFLD nomenclature conf in Chicago organized by international organizations. Time for the hepatology community to unify for our patients well being! ⁦ @AASLDtweets ⁩ ⁦ @EASLnews ⁩ #livertwitter ⁦ @AlkhouriNaim ⁩ ⁦ @schattenbergJ ⁩ ⁦⁦ @AlinaAllenMD ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Extra love and wanting to play with daddy when daddy is reading the final draft of a grant resubmission!! 😍 🤷‍♂️ #medtwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

This is an interesting study…. Semaglutide decreases #alcohol #drinking ! Treatment for BASH?!! @AleksanderKrag @Dr_Vijay_Shah @rabataller @juanpabloarab @JuanAbraldes @AlkhouriNaim @nagachalasani @novo #livertwitter @DrMTLong @SagiZelber @JVLazarus

The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates...

Growing evidence indicates that the glucagon-like peptide-1 (GLP-1) system is involved in the neurobiology of addictive behaviors, and GLP-1 analogues may be used for the treatment of alcohol use...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

8 months

A blood test to diagnose NASH and significant fibrosis (NASH >=F2). Will be available in the US within few months #livertwitter #gitwitter @novonordiskmed @MadrigalPharma @akerotx @Innov_Medicine @VCU_Liver @AlkhouriNaim @juanpabloarab @RMayo_OWL @OWLMetabolomics @CAlonso_OWL

SurfingMASH

@surfing_MASH

8 months

#NITs #NASHpodcast #SurfingNASH #FattyLiver

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Mazen Noureddin, MD, MHSc

@NoureddinMD

7 months

Chilling in Chile with great friends and Colleague at #SPED2023 @juanpabloarab @MMendizabalMD @FcoIdalsoaga @LuisAntonioDiaz @GCastro_NarroMD @ggarciatsao #livertwitter #gitwitter @alehlatam

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

علاج تشحم الكبد (دهن الكبد) : انقاص الوزن الزائد (شوف فيديو دكتور معتز @drmoutaz ) اما العلاج الدوائي فهو محدود. في اميركا البعض يستخدم فيتامين E او pioglitazone وهو لعلاج المرض السكري. الابحاث العلمية مستمرة ونتوقع اول علاج خلال أشهر @wedocaresaudi #كبد #طبيب

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Mazen Noureddin, MD, MHSc

@NoureddinMD

9 months

Introducing MASEF:🩸metabolomics based to assess at-risk NASH (NASH w NAS ≥4 + ≥F2) 👉🏻Performed Similar to FAST 👉🏻 FIB-4+MASEF = FIB-4 + VCTE 👉🏻International Multicenter 📖 #livertwitter @QAnstee @AlkhouriNaim @phil_newsome7 @OWLMetabolomics @ebtapper

Serum identification of at-risk MASH: The metabolomics-advanced steatohepatitis fibrosis score...

MASEF is a promising diagnostic tool for the assessment of at-risk MASH. It could be used alternatively to LSM by VCTE in the algorithm that is currently recommended by several guidance publications.

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Work led by Emily Troung an outstanding IM resident showed that although Asian Americans are leaner they have similar NAFLD disease severity. Nonalcoholic fatty liver disease prevalence and severity in Asian Americans from NHAENS #livertwitter ⁦

Nonalcoholic fatty liver disease prevalence and severity in Asian Americans from the national...

Studies have examined nonalcoholic fatty liver disease (NAFLD) prevalence and severity in Asians; however, this is not well understood in Asian Americans (both East and South Asian Americans) as few...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

10 months

If you are wondering about the future of NAFLD/MASLD the @TheLancet has published data showing that 1.31 Billion People could be living with T2DM by 2050!! #LiverTwitter @AlkhouriNaim @marurinella @AASLDtweets @AmerGastroAssn @WRayKimMD @ChengHanNg

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence...

Bill & Melinda Gates Foundation.

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

During my work with Vinay I witnessed him saving so many lives! I pray for miracle to save his life! @lilydaramd @ebtapper @DrLiver @RajivJalan1 @KowdleyMd @AlkhouriNaim @LaurenNephewMD @AnandVKulkarni2 @ArpanPatelMD

AASLD

@AASLDtweets

2 years

We've learned that a valued member of our community @VinaySundaramMD experienced a health emergency yesterday. We’re heartbroken to hear this news, and are keeping him and his family in our thoughts and prayers.

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Check out our new paper w @AlkhouriNaim @GileadSciences @novonordisk showing where NASH treatment is heading. It will be a combination therapy similar to the diabetes field. @loomba #livertwitter #GITwitter @JHepatology @surfing_NASH @LancetGastroHep

Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients...

Non-alcoholic fatty liver disease and its more severe form, non-alcoholic steatohepatitis (NASH), are serious liver conditions that worsen over time if untreated. The reasons people develop NASH are...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

A new paper @NatureMedicine that we wrote with friends & great minds @AlinaAllenMD @AlkhouriNaim #stephenharrison #julie summarizing issues in the NASH trials landscape #LiverTwitter #gitwitter #MedTwitter

Challenges and opportunities in NASH drug development - PubMed

Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical need, as no licensed drugs have...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

7 months

New player in MASH treatment. HU6 a mitochondrial uncoupler. Great PDFF reduction in 61 days only! In coll w @VCU_Liver @RivusPharma @MeenaBBansal @juanpabloarab @AlkhouriNaim @nagachalasani @ebtapper #livertiwtter

The Lancet Gastroenterology & Hepatology

@LancetGastroHep

7 months

New research - Noureddin et al - Safety and efficacy of once-daily HU6 versus placebo in people with non-alcoholic fatty liver disease and high BMI: a randomised, double-blind, placebo-controlled, phase 2a trial #LiverTwitter #NASH #MASH @NoureddinMD

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 months

#MASLD precision medicine conf in Las Vegas! Come join us #livertwitter #gitwitter

AASLD

@AASLDtweets

3 months

The ETC's Program Chairs bring a wealth of knowledge, experience, and a personal dedication to advancing the understanding of #MASLD through the lens of precision medicine. Explore the full program: #LiverTwitter #AASLDETC @WRayKimMD @NoureddinMD

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 months

Implementation of FIB-4 is very important to screen high risk #MASLD population but data from our group and @WRayKimMD emphasizes that we need to continue improving the tests/process #livertwitter @AGA_CGH

Degree of Discordance Between FIB-4 and Transient Elastography: An Application of Current Guideli...

Using FIB-4 in the AGA/AASLD guidelines to risk-stratify subjects at risk for MASLD-associated fibrosis results in many subjects being misclassified into the low- and high-risk categories. Therefore,...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

أعراض أمراض الكبد هي التعب (أو) الخمول، ألم في الطرف الأيمن من البطن، الحكة، وفي المراحل المتقدمة سائل في البطن (الحبن)، أو اصفرار العينين أو نزف هضمي (استفراغ دم لا سمح الله). العلاج متواجد لمعظم الحلات فاسأل مختص. @wedocaresaudi @drmoutaz

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

#TLM22 when you run into the people who trained you within the hepatocyte!!! ⁦ @NASH_and_coffee ⁩ ⁦ @NoureddinNabil ⁩ ⁦ @AASLDtweets ⁩ ⁦ @livertox ⁩ ⁦ @DavidKleiner12 ⁩ ⁦ @ChrisKohMD ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

A honor to speak @EASLedu NASH Summit in Dublin about serum based non invasive tests in #NASH #livertwitter

EASL Education

@EASLedu

2 years

👉 @NoureddinMD : Combination of serum biomarkers and imaging ➡��way to go for #NAFLD staging and treatment response #NAFLDsummit @gastaldelli_amy @lucavalenti75 @aelsharkawy75 @RuiCastroHD

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

@RanaAwdish I am 7 years out of fellowship and I am already thinking about taking dragon drawing lessons!!

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Our editorial for recent paper by @VWSWong on the possible + effects of ACEis. @Duke_liverdoc #livertwitter @naim @DrLoomba @NASH_and_coffee @AlinaAllenMD ACE inhibitors: The Secret to Prevent Cirrhosis Complications and Hepatocellular Carcinoma in NAFLD?

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Hepatologists and Hep NPs/PAs. You manage so many NAFLD pts and u wonder which diet and food you should tell them to eat? Here is the most updated literature presented in a webinar. 👇🏼. Join us this Wed. @AASLDtweets #GITwitter #livertwitter #dietitian #NAFLDSIG

AASLD

@AASLDtweets

4 years

Register for the "Dietary Recommendations for #NAFLD Patients" webinar on Wednesday, August 19 at 12 pm ET. Presenters: @DrMTLong #ZacharyHenryMD #ManuelGomezMD Moderator: @NoureddinMD Learn more & register 👉 #LiverTwitter #GITwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

9 months

#Houston Methodist Hospital has risen in the ranking. We are #5 in the US in GI & our transplant volume has been 2nd and could be #1 soon ;) #livertwitter #gitwitter @AASLDtweets @AmerGastroAssn @EASLnews @AlkhouriNaim @MethodistHosp @nagachalasani @MMendizabalMD @AleksanderKrag

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

أخ عنده دهن الكبد مع خشونة (مرحلة ٢ من ٤) قبل التليف و أجيبه: ✨الخشونة يمكن أن تزول مع خسارة ١٠٪ أو أكثر من الوزن ✨أفضل الحميات هي التي تقلل فيها من السكريات ✨الوصول للتليف يستغرق سنين عديدة ✨أبتعد عن المشروبات الغازية مثل الببسي @wedocaresaudi @wedocaresaudi @arabdiet

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Harvey Alter, Charles Rice and Michael Houghton won the 2020 Nobel Prize for Hep C discovery. I had the honor to work with Harvey during my fellowship at the NIH. Brilliant, Funny and most importantly Nicest guy ever. #MedTwitter @AlkhouriNaim @NoureddinNabil @NASH_and_coffee

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

NASH Cirrhosis ETC ⁦ @AASLDtweets ⁩ . #Stephenharrison discussing NASH cirrhosis trial design ⁦ @AlkhouriNaim ⁩ ⁦ @DrLoomba ⁩ ⁦ @marurinella ⁩ ⁦ @AlinaAllenMD ⁩ ⁦ @Mayo_liverdoc ⁩ #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

Today is #NASHDay the most common #liver dz and leading cause of #cirrhosis . Thanks to @GlobalLiver for your awareness program and @DCPatient for organizing these must watch webinars! Thanks to @AASLDtweets and @EASLnews for the ongoing support to battle the dz #LiverTwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

I found a new friend to hang out with at the AASLD meetings! Congrats @NoureddinNabil on ur match in the T32 @UCSD_GI GI fellowship. @AlkhouriNaim @DrLoomba #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 month

MASH clinical trials and drugs pipeline: An impending Tsunami . Update Review on MASH Drugs #livertwitter #gitwitter ⁦ @NaimAlkhouri ⁩

MASH clinical trials and drugs pipeline: An impending Tsunami - PubMed

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as NAFLD, has ascended to prominence as the predominant chronic liver disease in Western countries and now stands as a...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

شرب القهوة يساعد في إزالة دهن الكبد و يحسن خشونته @wedocaresaudi @drmoutaz @arabdiet @mohapuae @MOH_Bahrain @sayidatynet

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Mazen Noureddin, MD, MHSc

@NoureddinMD

11 months

The new nomenclature for NAFLD is now MASLD (Metabolic-dysfunction associated Steatotic Liver Disease) #LiverTwitter @EASLnews @marurinella @AASLDtweets @AlkhouriNaim @JVLazarus @NASH_and_coffee @lilydaramd @AASLDPresident

Juan Pablo (JP) Arab, MD 

@juanpabloarab

11 months

🚨 Hot of the press! New #MASLDNomenclature ! @AASLDtweets @alehlatam @EASLnews @Hep_Journal [] #LiverTwitter @LuisAntonioDiaz @MarcoArreseMD @NoureddinMD @AlkhouriNaim @marurinella @AASLDPresident @WRayKimMD @mromerogomez @DrLoomba @JVLazarus @mqkMD

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Mazen Noureddin, MD, MHSc

@NoureddinMD

6 months

The DUET study is the first phase 2 Placebo Controlled Combo RCT in MASH that is positive. Presented today #TLM2023 #LiverTwitter @AlkhouriNaim @NASH_and_coffee @JVLazarus @schattenbergJ

The Lancet Gastroenterology & Hepatology

@LancetGastroHep

6 months

In the late breakers, @NoureddinMD presents data from a ph 2a trial combining a THR beta agonist and an FXR for patients with presumed MASH #TLM2023 #TLM23 #LiverTwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Asking my 3 year old who my vote should go for though i am already biased #TLMDx #aasldtweet

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Drink Water and No #Sodas or Diet Sodas please!! ⁦ @AGA_CGH ⁩ @USC ⁦ @AlinaAllenMD ⁩ ⁦ @AlkhouriNaim ⁩ ⁦ @Mayo_liverdoc ⁩ ⁦ @novonordisk ⁩ #livertwitter

Sugar-Sweetened Beverage, Diet Soda, and Nonalcoholic Fatty Liver Disease Over 6 Years: The...

Nonalcoholic fatty liver disease (NAFLD) is associated with sugar-sweetened beverage (SSB) consumption in cross-sectional studies. In a prospective cohort, we examined the association of beverage...

www.cghjournal.org

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

Friday text from ⁦ @AlkhouriNaim ⁩ . Semaglutide approved for weight loss. Once a week injection up to15%weight loss!! NASH P3 is ongoing. #livertwitter #medtwitter #gitwitter @NASH_and_coffee ⁩ ⁦ @KathleenCoreyMD ⁩ ⁦ @DrMTLong ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

11 months

@AlkhouriNaim presenting the NAIL NIT data (> 5000 patients from NASH trials) @EASLnews in Vienna #LiverTwitter @AlinaAllenMD @rajVuppaLanchi @AleksanderKrag @DrLoomba @marurinella @mcharltonmd

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Someone promoted and supported you so make it your passion to support and promote others. One day your life will flash before your eyes. Make sure it is worth watching. #Academia #AcademicTwitter #MedTwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Came to round on our liver floor to see this #livertwitter ! Great job to our fellows and residents ⁦ @RikiGravesMHA ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

6 months

What is a hepatologist doing in #kidneyeek @ASNKidney ? 1) reapplying for Nephro fellowship 2) spreading the word about #MASLD #FIB4 #livertwitter @marurinella @AlkhouriNaim @NASH_and_coffee @AlinaAllenMD @NoureddinNabil @JVLazarus @AASLDtweets

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Mazen Noureddin, MD, MHSc

@NoureddinMD

11 months

Happy #Fatherday to all my GI, Hepatology and Doctors Friends and Papas ! #livertwitter ⁦ @AlkhouriNaim ⁩ ⁦ @DrLiver ⁩ ⁦ @nagachalasani ⁩ ⁦ @mcharltonmd ⁩ ⁦ @NASH_and_coffee ⁩ ⁦ @ChrisKohMD ⁩ ⁦⁦ @NoureddinNabil ⁩ ⁦ @DrLoomba ⁩ #gitwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

Happy 4th! Friday 6 Pm scope for GI bleed followed by urgent consult for a TIPS on a blakemore! Dear Interns, thats why we signed up for this.. saving lives. BBQ with masks tomorrow!! @AlkhouriNaim #Medtwitter #livertwitter @Sarah_Mojarad #TipsForNewDocs

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Mazen Noureddin, MD, MHSc

@NoureddinMD

10 months

The 2022 IF of @AGA_CGH is 12.6! This is holding at the same range despite drop in most journals. Also please check the special issue on Liver Dz @AlkhouriNaim @schattenbergJ @nagachalasani @SeragHashem @KanwalFasiha @drkeithsiau #livertwitter #gitwittter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

Sadly in liver disease we lose patients due to #cirrhosis but I have never lost as many as this week and all due to #COVID19 . Heartbreaking #MedTwitter #liverinfo #StayAtHome

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Mazen Noureddin, MD, MHSc

@NoureddinMD

9 months

Wegovy (semaglutide 2.4 mg) MACE @by 20% in adults with overweight or obesity in the SELECT trial🤩 #livertwitter 👇🏼 @ebtapper @JonathanStineMD @pgholam @LancetGastroHep @JVLazarus @AlinaAllenMD @novonordisk

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with NAFLD - Brilliant study by ⁦ @lucavalenti75 ⁩ #livertwitter ⁦⁦ @EASLedu ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

سألت أخت عن نتائج الفايبروسكان. شوف صورة شاشة الجهاز. الرقم الأزرق هو نسبة الدهون. الرقم البرتقالي(الرقم الأهم) هو نسبة الخشونة و التي قد تؤدي إلى تليف الكبد. الرقم البرتقالي أقل من ٦.٥ هو طبيعي أو قريب الطبيعي. أما إذا كان أعلى فناقش الأمر مع طبيبك. @drmoutaz @wedocaresaudi

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Dr. @AlkhouriNaim presenting at the Royal Society in London! Also wonderful tour at the Society (One pic is their first journal and the other is Newton’s handwriting)!! #ILC2022 #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Stephen Harrison ⁦ @Pinnacle_TX ⁩ presenting Imp data on #Resmetirom showing decrease in liver and spleen in cirrhotics! Also the durg was safe #ilc2022 #livertwitter ⁦ @AlkhouriNaim ⁩ ⁦⁦ @MadrigalPharma ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Good morning everyone #TLMDX #Livertwitter from the west coast. You were supposed to be here ! Looking forward to seeing you online @AlkhouriNaim @NASH_and_coffee @AlinaAllenMD @DrMTLong @DrLoomba @sidbarritt4 @RajVlanchi @KathleenCoreyMD @schattenbergJ @drmoutaz @NoureddinNabil

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Intercept Pharmaceuticals Announces REVERSE Phase 3 Study of Obeticholic Acid (OCA) in Compensated Cirrhosis due to NASH Did Not Meet its Primary Endpoint #livertwitter #GITwitter @AlkhouriNaim @surfing_NASH @schattenbergJ

Intercept Pharmaceuticals Announces REVERSE Phase 3 Study of Obeticholic Acid (OCA) in Compensated...

Company remains on track to resubmit new drug application (NDA) for OCA in its lead indication of fibrosis due to NASH by year end based on its positive...

www.globenewswire.com

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

With a push of a button our ML model (based on clinical variables) can predict F2, F3 and F4 as well @as NASH and F2 and higher better than Fibroscan and its scores!! @AlkhouriNaim @NASH_and_coffee @KowdleyMd @ebtapper @AleksanderKrag @nagachalasani @lilydaramd #livertwitter

HEPATOLOGY Journal

@HEP_Journal

1 year

Chang D et al. Machine learning models are superior to noninvasive tests in identifying clinically significant stages of NAFLD and NAFLD‐related cirrhosis @NoureddinMD #LiverTwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Thank you #helio & #WCIRDC @yhandelsmanmd . It is time to screen for NAFLD in Type 2 Diabetes patients. That will save many lives and data support that @scottisaacsmd @Yoav_Rotman @AlkhouriNaim @LiverSaver @GlobalLiver #endotwitter #medtwitter #GITwitter

Healio

@GoHealio

2 years

Screening for NAFLD should be conducted in all high-risk patients, including those with type 2 #diabetes , and there are several promising agents on the horizon for treating advanced fibrosis, according to @NoureddinMD . #WCIRDC2021 @WCIRDC

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Mazen Noureddin, MD, MHSc

@NoureddinMD

11 months

Finally the paper is out. Multi-center study from the US to address the Agile 3+ and Agile 4 cut offs and accuracy #LiverTwitter @ebtapper @rajVuppaLanchi @AlkhouriNaim @Echosens @NoureddinNabil

Hepatology Communications

@HepCommJournal

11 months

📑 Increased accuracy in identifying #NAFLD with advanced fibrosis and cirrhosis! ⭐️ Agile 3+ & 4 scores performed superiorly to FIB-4 & LSM by VCTE & maintained good accuracy for diagnosis of adv fibrosis and cirrhosis! #LiverTwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Keep praying for Vinay @VinaySundaramMD we are still hoping for a Miracle!!!! #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Most recent update on #NASH therapies landscape. Stay tuned for a special liver issue coming out via @AGA_CGH #livertwitter #GITwitter @nagachalasani @AlkhouriNaim @schattenbergJ @juanpabloarab @marurinella @DrMTLong @drkeithsiau @NatureMedicine

Clinical Trial Landscape in NASH - PubMed

Nonalcoholic fatty liver disease consists of a spectrum starting from nonalcoholic fatty liver disease that may progress to nonalcoholic steatohepatitis (NASH), which can lead to fibrosis, cirrhosis,...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

This international study deserves highlighting. Does it challenge the current guidance using FIB-4 as first test for screening!? Not the first time FIB-4 falls short @AlkhouriNaim @wonglaihung @VWSWong @LITMUS_IMI @QAnstee @DrLoomba @MajaThiele @AGA_CGH

Low Accuracy of FIB-4 and NAFLD Fibrosis Scores for Screening for Liver Fibrosis in the Population...

FIB-4 and NFS are suboptimal for screening purposes due to a high risk of overdiagnosis and a non-negligible percentage of false-negatives, especially in patients with risk factors for chronic liver...

pubmed.ncbi.nlm.nih.gov

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

After a long day in the hospital seeing sicker than usual liver patients my Neighbor made my day 👏 #SocialDistanacing #WeAreInThisTogether @NoureddinNabil @NASH_and_coffee

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

President of ⁦ @alehlatam ⁩ and ⁦ @AASLDPresident ⁩ open the discussion about the #NAFLD nomenclature led by ⁦ @marurinella ⁩ ⁦ @phil_newsome7 ⁩ And ⁦ @KanwalFasiha ⁩ ⁦ @EASLnews ⁩ @bcm_gihep ⁩ #livertwitter @ddw2023 ⁦

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

👇🏼The offical document of #NAFLD guidelines is out online led by @marurinella #livertwitter #MedTwitter #GITwitter @AlkhouriNaim @AlinaAllenMD @AleksanderKrag @DrLoomba

Maru Rinella MD

@marurinella

1 year

Amazing work by all - hope people find it helpful! @DrLoomba @JVLazarus @ebtapper @AlinaAllenMD @Mayo_liverdoc @NoureddinMD @GlobalLiver @liverUSA

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

Live with Nobel prize in medicine 2020 Drs. Rice, Alter and Houghton. #TLMDX

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Mazen Noureddin, MD, MHSc

@NoureddinMD

3 years

I am doing IM injections after years of not touching a needle and I just gave a #COVID19 to a pregnant #frontliner ... This is the highlight of my week 🙂 #GetVaccinated #StayAtHome

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

I dont like politics but she is talking about me and many many of us!! 👇🏼Lets start with the example of #FrontLineHeroes including doctors and nurses #Immigrants #EqualityForAll #MedTwitter

Lauren Witzke

@LaurenWitzkeDE

4 years

Most third-world migrants can not assimilate into civil societies. Prove me wrong.

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Does this count ? First successful attempt? @DrLiver @AlkhouriNaim #girldad

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 months

Thank you Dr. Anna Lok and #CROI2024 committee for the invite to talk about #MASH cirrhosis . It was great to be with Jenny Price after seeing ! ⁦ @AlkhouriNaim ⁩ ⁦ @ebtapper ⁩ in AZ! #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

Honored to speak in this congress 👇🏼 organized by @yhandelsmanmd and has world renowned speakers #RalphDeFronzo #SamKlein #GeraldShulman #LiverTwitter #nash #NAFLD @NASH_and_coffee @AlkhouriNaim @shadiabdelnour @GileadSciences @MadrigalPharma

World Congress on IR, DM & CVD 🌎

@WCIRDC

2 years

#WCIRDC2021 Program Highlight: Dr. Mazen @NoureddinMD will discuss the Diagnosis and Treatment of Patients with #NAFLD / #NASH in the Future. To see more of the #Liver session, register at @CedarsSinai @CedarsSinaiMed #medicalconference #meded #endoed

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Mazen Noureddin, MD, MHSc

@NoureddinMD

6 months

A special morning speaking about #MASLD and #MASH to my friends and colleagues at the Gastroenterology Society in #Ukraine #livertwitter

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Mazen Noureddin, MD, MHSc

@NoureddinMD

2 years

#LiverConnect @AlkhouriNaim wearing his Non-NASH hat and talking about liver disease In children. Fascinating talk #livertwitter #GITwitter #MedTwitter @DrLoomba @AlinaAllenMD @LiverArizona

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

#MATCH2021 Attending here, the most common two questions we ask in the interview 1) why you want to apply to our place? 2) where do see yourself 5 years from now?3) we also like to ask about hobbies :) Best advise: read the webpage where u interview #MedTwitter #IMRESIDENCY

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Mazen Noureddin, MD, MHSc

@NoureddinMD

4 years

اسباب تضخم الكبد عديدة أهمها هو تشحم الكبد الذي يترافق مع امراض السكر والبدانة او في الغرب ايضا مع شرب الكحول . الاسباب الاخرى عديدة مثل التهابات الكبد B و C, فيروسات اخرى. انصح بزيارة طبيب هضمية و امراض كبد اذا وجد هذا التضخم. @wedocaresaudi @drmoutaz

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year

Fascinating study by @mromerogomez and @LITMUS_IMI :many of our cohorts were combined @DrLoomba #livertwitter An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibrosis staging with magnetic resonance elastography

An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibro...

We conducted an individual patient data meta-analysis to establish stiffness cut-off values for magnetic resonance elastography (MRE) in staging liver fibrosis and to assess potential confounding...

www.journal-of-hepatology.eu

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Mazen Noureddin, MD, MHSc

@NoureddinMD

9 months

Texas Medical Center this Am! The largest in the world… another organ has arrived… saving lives ⁦ @MethodistHosp ⁩ ⁦ @bcm_gihep ⁩ ⁦ @HowardTLeeMD ⁩ #gitwitter #livertwitter ⁦ @AlkhouriNaim ⁩

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Mazen Noureddin, MD, MHSc

@NoureddinMD

11 months

Really imp study @AGA_CGH by @HannesHagstrom Risk of liver Bx in #NAFLD @AlkhouriNaim @DrLoomba @marurinella @schattenberg @nagachalasani @EASLnews @AleksanderKrag #livertwitter @ebtapper @GlobalLiver @US_FDA @JasmohanBajaj @JVLazarus @HenryEChang

Risk of Severe Infection in Patients With Biopsy-proven Nonalcoholic Fatty Liver Disease – A...

It has been suggested that patients with nonalcoholic fatty liver disease (NAFLD) might be at increased risk of severe infections, but large-scale data from cohorts with biopsy-proven NAFLD are...

www.cghjournal.org

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Mazen Noureddin, MD, MHSc

@NoureddinMD

1 year