Luca Valenti
@lucavalenti75
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MD, researcher, editor; Hepatology & Internal Medicine, Genetics; father of two; views are my own
Milano
Joined March 2015
RT @EricTopol: Adherence to a Mediterranean diet linked to reduced dementia-related metabolites, many of which showed causal relationships….
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RT @rabataller: 🚨 AI won’t replace doctors… but it can prevent them from learning how to think. A critical article in @NEJM shows that if….
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RT @NEJMEvidence: Statistical testing of more than one hypothesis has the potential to increase the risk of type I error. Amy LaLonde, PhD,….
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RT @davidasinclair: Optimizing Yamanaka factors for epigenetic age reversal . Congrats @OpenAI @RetroBio_ 👏
openai.com
OpenAI and Retro Biosciences achieve 50x increase in expressing stem cell reprogramming markers.
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Check it out: a short overview of the PNPLA3 research field and our Special Issue! Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics @LiverInt
onlinelibrary.wiley.com
Steatotic liver disease (SLD), caused by excess lipid accumulation in hepatocytes, is now a leading global liver condition triggered by metabolic dysfunction, alcohol, toxins and heritable factors....
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RT @EricTopol: A discovery of a gene underpinning the perception of pain with implications for treating the chronic condition that affects….
nature.com
Nature - The SLC45A4 gene encodes a neuronal polyamine transporter and is linked to pain response in humans and mice.
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RT @andganna: Impressive paper by EPIC. They built a autoregressive transformer on 150M individuals and 115 billion.medical events. Inclu….
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RT @EricTopol: Rejuvenating the brain of old mice by targeting ferritin light chain (FTL1)."Our data raise the exciting possibility that th….
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RT @NikoMcCarty: Mitochondria are known as the "powerhouses" of a cell. But that is a ridiculously incomplete description. A new study sho….
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This is worrisome.
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RT @AghemoAlessio: Today Resmetirom was approved by EMA for the treatment of F2-F3 MASH. Here is an article to learn more about Resmetiro….
onlinelibrary.wiley.com
The rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) poses a significant global health challenge, affecting over 30% of adults worldwide. MASLD is linked to...
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RT @NEJM: A new review discusses the global clinical burden and consequences of MASLD as a multisystem disease and focuses on the new and p….
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RT @MarcoArreseMD: @rabataller @EASLedu @AASLDtweets @AEEHLiver Fully agree. This table from Mangia & Valenti just published review is comp….
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RT @NEJM: Correspondence: A Naturally Occurring Gain-of-Function Mutation in Factor VIII . #Hematology #Cardiology….
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Safety Choice Drivers of the Coming Treatment Options for Non‐Cirrhotic Metabolic Steatohepatitis - Mangia - 2025 - Liver International - Wiley Online Library @LiverInt.
onlinelibrary.wiley.com
Metabolic dysfunction associated steatohepatitis (MASH), formerly known as NASH, represents one of the leading causes of chronic liver disease worldwide. Its high prevalence is driven by insulin...
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RT @MichaelAlbertMD: 🚨BREAKING: FDA grants accelerated approval to Wegovy (semaglutide 2.4 mg injection) for treating adults with non‑cirrh….
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RT @massimoiava: Additional indication for semaglutide 2.4 mg for treatment of non cirrhotic #MASH in adults with moderate to advanced live….
novonordisk.com
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Check out our latest review on MASLD! A metabolic liver disease. Fresh from the press @NEJM @LaStatale @policlinicoMI.
MASLD has become the most common chronic liver disease worldwide. Giovanni Targher, MD, Luca Valenti, MD (@lucavalenti75), and Christopher D. Byrne, MB, ChB, review the features of the disease as well as pharmacotherapies targeting the associated liver and
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RT @EricTopol: New @Nature .The possibility that lithium deficiency is a driver of Alzheimer's disease. Experimental model shows Li depleti….
nature.com
Nature - Lithium has an essential role in the brain and is deficient early in Alzheimer’s disease, which can be recapitulated in mice and treated with a novel lithium salt that restores the...
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