Ben Myers Lab
@Myers_lab
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Transmembrane signaling in development and cancer / Univ. of Utah
Salt Lake City, UT
Joined December 2017
RT @NBellono: Microbiomes shape our biology from gut-brain, skin, immunology, and more. Here, Rebecka Sepela et al explores octopus “taste….
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RT @cyclic_Andreas: Our recent take on localized #GPCR signaling @TsvetanovaLab @MiriamStoeber @bradenlobingier
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RT @MoritzMall: What keeps cancer cells in check—and can we tame hem? In 2 collaborative preprints, we trace glioblastoma cell transitions….
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RT @MatthewEddyLab: Excited to see our new article is out in @J_A_C_S, comparing conformational equilibria of a human GPCR in lipid vesicle….
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RT @jjanetzko: Our lab's first paper (w @NLKProteomics) is officially online at Analytical Chem today!! @an_chem . Excited for the opportun….
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RT @Kaochar2: Pursuing a PhD Is a Choice—And a Privileged One. First and foremost, pursuing a PhD is a path we choose. No one is forced int….
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RT @ProfBootyPhD: This is a really fascinating and important paper, on the mechanism of neurodegeneration in Huntington's disease. I often….
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RT @HHMINEWS: “My advice is to take as much time as you can with on-the-job training,” says HHMI Investigator Nels Elde. “That's how you fi….
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RT @gsducker: Happy New Year. I’m pleased to report publication of the Ducker lab’s latest cancer metabolism paper led by graduate student….
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RT @BiophysicsGuy: The Robertson lab has multiple openings for postdocs! Particularly interested in those with experience in either plate r….
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RT @huntsmancancer: Congratulations to Dr. Minna Roh-Johnson (@roh_johnson_lab) for receiving an award from @theNCI for excellence in diver….
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Very interesting mechanism for phosphorylation to block GPCR-G protein interactions. Nice work @atypicalGPCRs!.
Non-canonical regulation of canonical GPCR signaling. CCR9 should be an effective activator of G proteins, but is instead suppressed by a unique phosphorylation mechanism. Congrats to Thomas Lamme's first paper of his PhD!
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RT @biochem_stew: Second half of my PhD work is up on Biorxiv and I’m really happy how this story turned out. A kinase and phosphatase batt….
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Big thanks to everybody involved in this collaboration, led by co-first authors Will Steiner / Nate Iverson / Zac Michaelson (@Myers_lab); Varun Venkatakrishnan (Ganesh Anand’s lab); Jian Wu (Susan Taylor’s lab); @t00mek88 (Jana Selent’s lab)! @huntsmancancer @UofUHealth.👏🔬.
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RT @biorxiv_biochem: A Structural Mechanism for Noncanonical GPCRSignal Transduction in the Hedgehog Pathway #bior….
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This was a fantastic collaboration with Susan Taylor, @RolandDunbrack, and many others as well! . Check out the preprint for a deeper dive, and let us know what you think.
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Our work highlights AlphaFold's power in uncovering structures for challeinging complexes, especially those involving IDRs. We suspect that other GPCRs might also use phosphorylation-induced folding to engage new effectors.
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