Ben Myers Lab
@Myers_lab
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Transmembrane signaling in development and cancer / Univ. of Utah
Salt Lake City, UT
Joined December 2017
Myers lab @UUtah is hiring! Postdoc fellowships combining biochemistry / biophysics of transmembrane signaling with development and cancer models. Many exciting projects to choose from. Please RT! #Hedgehog #cilia #GPCR #kinase #development #cancer
https://t.co/DLAAA7qWcW
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So this was a nice thing that happened to me today. 😀
Join us in celebrating the #ASBMB26 Award Winners! #MakeItPossible • Monther Abu–Remaileh • Suzanne Barbour • @bradylabupenn • George Carman • Joseph @CotruvoLab • @RogerJDavis1 • @RolandDunbrack • Pamela Mertz • James @Olzmannlab • Kim Orth • Margaret Phillips
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Thrilled to share our collaborative paper on β-arrestin-2! 🎉 Combining MD simulations with experimental approaches, we reveal the early steps of C-tail displacement by ACKR3. Huge thanks to our amazing collaborators and everyone who made this possible! https://t.co/xFn7F13Wo3
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Deadline extended! Submit your abstract by August 8 to share your GPCR research Outstanding submissions will be selected for short talks and poster prizes — 🔬🧬📣 Don’t miss the chance to engage, present, and be recognized! Submit here --> https://t.co/WBxxh7vTfw
#ECIGPCR5
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My lab is recruiting post-docs! We study inter-organ communication using cutting-edge tools like proximity labeling (TurboID), in silico modeling (AlphaFold), and genome engineering (CRISPR). Come join us at @UofUGenetics, Utah is beautiful! (View from our fly room 👇)
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Microbiomes shape our biology from gut-brain, skin, immunology, and more. Here, Rebecka Sepela et al explores octopus “taste by touch” sensation to ask how environmental microbiomes drive animal behavior. @CellPressNews, @MCB_Harvard, @MBLScience
https://t.co/mxfkgoAVDA
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What keeps cancer cells in check—and can we tame hem? In 2 collaborative preprints, we trace glioblastoma cell transitions in space and decode what regulates their plasticity 🧠👇 📍 Spatial & multi-omic atlas: https://t.co/GNGoASIYCc 📍 Regulatory logic: https://t.co/j3D1N24HpW
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Excited to see our new article is out in @J_A_C_S, comparing conformational equilibria of a human GPCR in lipid vesicles, nanodiscs, and detergents. Great work from students @arka_ray1 and Beining (Kim) Jin! https://t.co/LPLOTNqTIB
#NMR #NMRchat
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Our lab's first paper (w @NLKProteomics) is officially online at Analytical Chem today!! @an_chem Excited for the opportunities this work brings to profiling heterogeneous membrane proteins like GPCRs. @CU_BMG @CUPharmacology @CUPharmacy @BioFrontiers
https://t.co/Jx3UiSJYD8
pubs.acs.org
G protein-coupled receptors (GPCRs) are the largest class of integral membrane receptors and responsible for transmitting diverse signals in response to extracellular stimuli. Post-translational...
Are there any scientists left here? If so, I've got a short story to tell! Excited to share our work on developing a practical approach to resolving intact GPCR proteoforms: https://t.co/SkuF3VfSTe A short 🧵
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NIH cuts are hitting young scientists the hardest. By David Baker.
timmermanreport.com
[Editor’s note: David Baker gave this speech to Seattle community leaders Mar. 10, at a celebration of his 2024 Nobel Prize in Chemistry.] Let me just briefly tell you how innovation arises in...
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Pursuing a PhD Is a Choice—And a Privileged One First and foremost, pursuing a PhD is a path we choose. No one is forced into it. There are plenty of career opportunities that do not require a PhD, and many of them offer stability, competitive salaries, and clear professional
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This is a really fascinating and important paper, on the mechanism of neurodegeneration in Huntington's disease. I often think single-cell 'omics is an overhyped approach, but it was completely essential here. 1/
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“My advice is to take as much time as you can with on-the-job training,” says HHMI Investigator Nels Elde. “That's how you find out if you become a basic scientist.” Learn more about Elde’s lab at @UUtah: https://t.co/XkxIY5An74
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Proud to share our work by a fantastic team, spear-headed by PhD student @Kainerox with major contributions by #xenopus expert @RosiFeistel. We developed an improved iAPEX-based #ProximityLabeling method for #massspec based subcellular #proteomics. https://t.co/0jDlrlkK7M
biorxiv.org
Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background...
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Happy New Year. I’m pleased to report publication of the Ducker lab’s latest cancer metabolism paper led by graduate student Kyle Dunlap in @CellReports. https://t.co/8t9MNLFV9z Thanks to @UofUBiochem! Full thread and other site
cell.com
Metabolic adaptations are key to cancer cell survival in nutrient-limited microenvironments, but strategies for coping with arginine scarcity are poorly understood. Dunlap et al. use CRISPR screening...
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The Robertson lab has multiple openings for postdocs! Particularly interested in those with experience in either plate reader assays or ML, but all are welcome!; come learn about GPCRs, cryoEM, MD/FEP, drug discovery and more! https://t.co/LXa6IYHM7O
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Congratulations to Dr. Minna Roh-Johnson (@roh_johnson_lab) for receiving an award from @theNCI for excellence in diversity and mentorship! This honor supports her groundbreaking research and commitment to inclusivity in science. https://t.co/CePoZU6m8O
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Very interesting mechanism for phosphorylation to block GPCR-G protein interactions. Nice work @atypicalGPCRs!
Non-canonical regulation of canonical GPCR signaling. CCR9 should be an effective activator of G proteins, but is instead suppressed by a unique phosphorylation mechanism. Congrats to Thomas Lamme's first paper of his PhD!
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Second half of my PhD work is up on Biorxiv and I’m really happy how this story turned out. A kinase and phosphatase battle to phosphorylate Stu2 which gave us insights into how cells regulate anaphase onset. @m_p_miller @biorxivpreprint
https://t.co/3FsDWwdD9e
biorxiv.org
Cells coordinate diverse events at anaphase onset, including separase activation, cohesin cleavage, chromosome separation, and spindle reorganization. Regulation of the XMAP215 family member and...
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