John Janetzko
@jjanetzko
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Asst. Prof. Univ of Colorado @CU_BMG. Chemist, sometimes structural biologist, bike racer 🚴🏼♂️, 👦 & 🐶 dad, 🇨🇦, 🎓 Stanford/Harvard/UToronto.
Denver, CO
Joined September 2009
Whenever I say something unsubstantiated from now I’ll just start with “respectfully”
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In the interest of promoting an understanding of the history, this scathing letter from Crick to Watson in 1967 is a remarkable document. Crick lays out a detailed criticism of the draft of Watson's "Double Helix" (provisionally titled "Honest Jim" here). https://t.co/yz1zGwufKL
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Lior Pachter’s dream analysis 😂
How I interpret the results of our latest crispr screen vs what the data actually show.
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One obvious thing we **should** have done when moving to electronic publication was switch to rich citations that point directly to what you are citing in a paper - a data point, a figure, a method, a conclusion - and explain why you are citing it. Another thing publishers
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Hooray!! The first major product from the lab is out today @Nature. Small molecules that bind the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.💥 Check it out! 👉 https://t.co/oO21BkoxVQ 🧵👇
nature.com
Nature - Studies of the G-protein-coupled receptor NTSR1 show that the G protein selectivity of this receptor can be modified by small molecules, enabling the design of drugs that work by switching...
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Our faculty in the Department of Pharmacology at CU Anschutz are driving biomedical research that makes an impact. Here’s to another year of discovery and collaboration! #ResearchExcellence #CUAnschutz
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The Lipid Brain Atlas is out now! If you think lipids are boring and membranes are all the same, prepare to be surprised. Led by Luca Fusar Bassini with Gioele La Manno's lab, we mapped membrane lipids in the mouse brain at high resolution. https://t.co/q3AeqGsIS1
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Our latest work: As it turns out different positive allosteric modulators bind to different sites at the mu opioid receptor. Find out more in our @biorxivpreprint. https://t.co/lorGBe427R
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“due to recent NIH actions, more than 4 in 5 early career researchers are considering leaving academia or relocating outside the US. When I directly pressed Bhattacharya about this exodus during our meeting, he said that if researchers did not like the way things are in the US /1
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Come join us 😃
Fred Hutch's Human Biology Division is recruiting a tenure-track Assistant or Associate Professor to lead a laboratory-based research program focused on the biological mechanisms of solid tumor cancers and their clinical translation. Learn more and apply: https://t.co/7abt8x92wu
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Check out my new crit bike 👀
Sergey Dashevsky won the Guinness World Record for the smallest functional bicycle in the world with a creation that measured just 8.4 cm (3.31 inches). Here's one of his performances. https://t.co/sjUdMuUxQT
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A lab that collects data together stays together. Feeling like the luckiest PI to work with such great folks 🤩🔬 @CUAnschutz @CUBIOCHEM1
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Proximity-specific ribosome profiling using LOV-BirA reveals two distinct strategies for mitochondrially-localized translation: one for long coding sequences and one for short. It was a pleasure to contribute to this beautiful work from Jonathan Weissman @JswLab and @JingchuanLuo
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Great opportunity!
A NOA from NIDA on a UG3 grant is here. Excited to work with Brian Kobilka and Jay Mclaughlin on NAMs for treating opioid overdose upto IND phase. Several postdoc positions in both chemistry/pharmacology available. @washumedicine @WashUClinPharm Please RT
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0.8% of direct costs for publishing would be ~2k total for a NIGMS MIRA - I think that would make a lot of journals (most journals?) off limits 😕
"NIH grantees should utilize as much of their grant funds as possible for research activities...[J]ournals with large publishing fees can lead awardees to pay unreasonably high fees from their NIH awards that lessen the funds available for conducting research"
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In the latest issue! Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes https://t.co/8CYaL7mr1a
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