Matteo Allegretti
@MatteoAll
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Cellular structural biology (cryo-EM/ET, biophysics) | nature, society | Group Leader at @MRC_LMB and father, prev. @MPIbp @embl | https://t.co/4fxzFaTL8W
Cambridge (UK)
Joined December 2011
Ever wondered if nuclear pore architecture and function changes during germ cell differentiation? In human spermatogenesis it does, and radically!!.Check out our first lab preprint @AliaCSantos et al! @PiotrKolata1 @AlisterBurt @TDendooven @MRC_LMB
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RT @lab_baum: 🎉 Finally out! 🎉 Thrilled to share our work on the evolution, structure and membrane remodeling of Asgard ESCRT-III proteins!….
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RT @DavidPosner13: 🚨 New article alert! 🚨.I wrote an article in @Nature about how anyone in a well-resourced lab can implement to democrati….
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RT @jgreener64: I have two job adverts open at the minute:. - A PhD position on fast MLIPs for biomolecules (. - A….
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RT @ben808080: @AdrianoAguzzi How about adding something like this to the author contribution section ? ."The authors agree that equally co….
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This fascinating journey through sperm cell differentiation would not have been possible without the great collaboration with David Barford lab, @TomHale1040915, EM facility @gcannonii, and LM facility! Enjoy the read!!
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After meiosis nuclear pore architecture changes drastically resulting in a reduced scaffold with only the inner ring present. We find that the pore’s central channel is highly constricted, slowing down nuclear diffusion, and that Ran dependent transport is severely perturbed!
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RT @JamesDManton: Thanks to @royalsociety and @MRC_LMB, @lab_baum and I are looking for a student to develop the next generation of fluores….
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RT @NobelPrize: BREAKING NEWS.The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to….
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RT @InesJCastro: Thank you everyone for everything peripheral: Lamins, LADs, NPCs, LINC comp, laminopathies, peripheral chromatin et al! Gr….
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RT @svenklumpe: Check out JP’s virtual lift-out experiment that made it on the cover of Nature Methods!.
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RT @KellyTHD_Nguyen: Come and join this amazing group of scientists to work at the cutting edge of structural biology of telomeric complexe….
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RT @GaiaPigino: Over the moon about this work! 🤩 .Sam @Samlacey combines cryo-EM, #teamtomo magic, #AlphaFold, and structural proteomics (w….
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Join our fantastic EM facility team!All latest high end instrumentation available!.
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