Michael Iskols
@MIskols
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|| @TriIMDPhD || formerly: the Ginty Lab @harvardmed studying touch, pain, and sexual function
Joined June 2022
Incredibly excited to share our (@leonard_qi) preprint from the Ginty Lab studying the Krause corpuscle, a population of sensory endings in the genitalia that detect light touch and vibration to enable proper sexual behavior. They’re pretty cool looking too :)
Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior #biorxiv_neursci.
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RT @AnnieLHsieh2: 🎉Exciting news! Our latest work on Glioma-Innervating Neurons has just been published in PNAS!🔗 Read the full article her….
pnas.org
Gliomas are the most common malignant primary brain tumor and are often associated with severe neurological deficits and mortality. Unlike many can...
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RT @ScienceMagazine: This brown bear is performing a “wet dog shake”—a stereotypical behavior observed in most mammals when they get wet or….
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RT @AbhiLenka11: Exciting discovery: CSF flow isn't confined to the brain and spinal cord—it also extends to peripheral nerves! @ScienceMag….
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RT @MichaelLinLab: Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on….
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!!!.
🚨❗️🚨 New Paper Alert.My postdoctoral work now out in @Nature. We find that sensory neurons drive breast cancer metastasis via an activity-dependent paracrine signalling mechanism mediated by substance-P, extracellular ssRNA & TLR7 receptor. (1/11)..🧵👇🏾
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RT @YIgbaria: I'm thrilled to announce that our latest research on chronic vulvar pain has been published in Brain!..
academic.oup.com
Provoked vulvodynia is a neurological pain syndrome associated with recurrent inflammation, mast cell accumulation, and vulvar neuronal sprouting. Awad-Igb
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RT @ElaineFuchsLab: Welcome @MIskols to the lab for your rotation! Here posing with @CharlesXu3 in the neuro team uniform 👏🏼 .
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Alternate career path?.
Also check out the Nature podcast that talked about our work with @MIskols
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I’ve been incredibly fortunate to work with @leonard_qi on this project over the recent years; we explore a dense population of vibration-sensitive neurons in the genitalia and their contribution to sexual behavior (now including the clitorovaginal reflex)
nature.com
Nature - Krause corpuscles of the clitoris and penis are highly sensitive mechanical vibration detectors that mediate sexually dimorphic mating behaviours in mice.
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RT @KhannaLabUF: HOWZAT!!!.Nav1.7 as a biomarker of peripheral nerves in mice and primates!!! A fluorescently-tagged 🇵🇪 tarantula NaV1.7-ta….
biorxiv.org
Surgeries and trauma result in traumatic and iatrogenic nerve damage that can result in a debilitating condition that approximately affects 189 million individuals worldwide. The risk of nerve injury...
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RT @doctorveera: A GWAS of having never experienced a headache in life revealed a signal near ADARB2, which encodes an RNA editing enzyme e….
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RT @biorxivpreprint: Netrin G1 Ligand is a new stromal immunomodulator that promotes pancreatic cancer #bioRxiv.
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RT @SWC_Neuro: Researchers at SWC, @UCL, @Cambridge_Uni, @Harvard and @AllenInstitute have developed, used and evaluated Repix, a chronic i….
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RT @JankowskiLab: Excited to finally see @AdamDourson new paper available online now! .Macrophage memories of early-life injury drive neon….
cell.com
Dourson et al. investigate the effects of injury on peripheral macrophages and how they contribute to neonatal nociceptive priming. Macrophages are essential regulators of this phenomenon through...
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RT @AdamEzraCohen: Does the uterus have a pacemaker? Where do uterine contractions originate? We took a look!.https….
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RT @biorxivpreprint: Interleukin-6 induces nascent protein synthesis in human DRG nociceptors via MNK-eIF4E signaling .
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RT @LabWaggoner: Androgen signaling skews skin immunity toward reduced inflammation in male mice @ScienceMagazine @BelkaidLab . https://t.co….
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