Gregory Lesinski
@LesinskiLab
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The Lesinski Laboratory is focused on understanding the interactions between the immune system and cancer. opinions are my own. #immunotherapy #GICancer
Georgia, USA
Joined November 2016
Very lucky to work with these all stars!.
Honored to be awarded the All-Star V Foundation grant! Inspired by great team efforts between @PaulosLab @LesinskiLab! Props to cell therapy gurus @megen_wittling @AnnaCamille98 #MeganWyatt @WinshipAtEmory!
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Congrats to our collaborators @PaulosLab @Chrystal_Paulos @AnnaCamille98 @hknochelmann @WinshipAtEmory on this tremendous @Cancer_Cell work! Comprehensive tweetorial below. Punchline: Th17 therapy needs the B cells! #Tcell #immunotherapy #Bcell.
BREAKING: We uncovered a potent immune alliance that could change how we treat solid tumors. Published in @Cancer_Cell , we show that Th17 cells *must* work with B cells to eliminate tumors—and keep it from coming back. 📄 🧵1/12👇Let’s walk through it:.
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High impact report from @Zihai with many other superb @OSUCCC_James colleagues @CarsonLabOSU and more on #nkcell and #tcell interactions. Check it out!!.
Are #NK_cells friends or foes in cancer #immunotherapy? We found they impede the development of anti-tumor NK-regulated T cells (#NKRTs). A separate study by @lab_marine showed that NK cells contribute to ICB resistance in melanoma.
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Check out our new paper in Hepatology on how myeloid cells limit #immunotherapy in preclinical #cholangiocarcinoma models! .Disease site matters! Collaborative effort with @Chrystal_Paulos and many others @WinshipAtEmory @KimmelCancerCtr @VanderbiltU .
pubmed.ncbi.nlm.nih.gov
These findings identify myeloid cells as key mediators of both immunotherapy resistance and toxicity in CCA, highlighting the critical importance of tumor site and use of physiologically relevant...
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Cool pre-print alert! @Chrystal_Paulos @megen_wittling @PaulosLab @WinshipAtEmory offer new insight into how neoAg help adoptively transferred #Tcells traffic!.
Checkout our teams new work by @megen_wittling et. al. @WinshipAtEmory on how neoantigens drive adoptively transferred CD8 T cells to long-lived effectors mediated by lymph node trafficking | bioRxiv
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Congrats to this outstanding team @IamLinghua @Aiims1742 and many others on important #pancreaticcancer research that likely took many dedicated years to do!!.
Thrilled to share our latest study just out in @Nature 😄A major milestone in our collaboration with @Aiims1742 Led by brilliant @GuangshengPei @jiminmin_v @MDAndersonNews
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RT @sitcancer: The Advances in Cancer Immunotherapy™: A Focus on Gastrointestinal Cancers program on April 23, features in-depth clinical e….
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Outstanding day of impactful cancer research bringing together @universityofga and @WinshipAtEmory!.
Thanks to @universityofga for hosting the exciting joint symposium between @WinshipAtEmory and @universityofga Cancer Center. Our partnership continues to grow strong! @AdamMarcusPhD @LesinskiLab @EmoryUniversity
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High-Dimensional Protein Analysis Uncovers Distinct Immunological and Stromal Signatures Between Primary and Metastatic Pancreatic Ductal Adenocarcinoma Excited to share our new preprint comparing primer and metastatic HUMAN #pancreaticcancer!.
biorxiv.org
Our understanding of the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME) primarily stems from murine models or primary patient tumors. While metastatic tumors have generally less...
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Time is running out! #postdoc event @WinshipAtEmory apply now!.
Join us on March 13-14, 2025, for postdoctoral recruitment event at Winship! Network with mentors and postdocs, and explore Emory's research and career resources. 📅 Apply by January 31, 2025 🔗 Details & Application:
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Imp study led by @BasselElRayesMD and others on new combo chemo in #pdac. Honored to collab in this effort!. Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine: Cell Reports Medicine
cell.com
Nagaraju et al. have identified that paricalcitol (P) plus hydroxychloroquine (H) potentiates the efficacy of gemcitabine (G) in PDAC. GPH treatment induces ER stress and autophagy with M1 polariza...
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Calling all #postdocs!!!! @WinshipAtEmory wants YOU! Please apply if interested in exploring our collaborative environment to launch your career!.
Join us on March 13-14, 2025, for postdoctoral recruitment event at Winship! Network with mentors and #postdocs, and explore Emory's research and career resources. 🔗 Details & Application: #PostdocOpportunities #CancerResearch #WinshipResearch
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I’ve moved to #BSKY as well. Check LesinskiLab on the platform and let’s start over. Looking forward to a more positive science focused experience!.
Signed up for #BSKY account too. Will be posting there for #immunotherapy and #melanoma #Bridge2024 in Napoli too. @BernardAFox @LesinskiLab @sitcancer @DrBetofMDPhD @WinshipAtEmory @PAscierto @PoseyLab.
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Check out the difference between cells in primary and metastatic #pancreaticcancer at poster 890 #SITC24 from brilliant postdoc @natalie_horvat @WinshipAtEmory
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Congrats to my collaborator @Chrystal_Paulos @WinshipAtEmory @EmorySurgery a true #trailblazer for her pioneering cell therapy work! Congrats to her and the other bright stars noted as awardees below from @EmoryMedicine!.
As part of Faculty Recognitions Week, we congratulate members of our faculty who've been recognized with the Excellence in Research: Trailblazer Award. Recognizing faculty who engage in outstanding/cutting-edge research that advances our knowledge base.
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A day of collaboration is near….Please check out and register to see collaborative science between @WinshipAtEmory @GACancerCenter @GeorgiaTech @universityofga @GeorgiaStateU @CAU and more!.
Join us for the annual Winship Scientific Symposium at the Emory Conference Center Hotel on Monday, Nov. 11, 2024. Registration is complimentary and includes meals and refreshments. ➡️Register today:
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Congrats to our fabulous colleagues @Maria_Carden1 @HaydnKissick et al @WinshipAtEmory for this remarkable #Tcell paper! Very happy to see this out!.
Congratulations to @Maria_Carden1 and @HaydnKissick for their work on the significance of stem-like CD4 differentiation in cancer, published today in @Nature ! It’s a must-read for anyone interested in cancer immunology!.
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Congrats to @zach_buchwald and colleagues @WinshipAtEmory on this high impact work on #brainmetastasis.
Plz check out our new paper on pre-op SRS and the immune microenvironment of human brain metastases. Big team effort: @careyjans @meghatron2016 @HaydnKissick @Maria_Carden1 @MohammadKhanMD and many more.
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