Paulos Lab
@PaulosLab
Followers
2K
Following
5K
Media
600
Statuses
3K
T cell specialists lab! @EmorySurgery @WinshipAtEmory
Atlanta, GA
Joined May 2011
RT @PaulosLab: Check out Dr. @GuillermoORang1's new Cancer Research paper. We show that not all stem-like memory CD8 T cells are equal. ….
0
3
0
Check out Dr. @GuillermoORang1's new Cancer Research paper. We show that not all stem-like memory CD8 T cells are equal. Progressively enhancing stemness of adoptively transferred T cells with PI3Kδ blockade improves metabolism and anti-tumor immunity
1
3
29
Newest preprint paper by our team (@LesinskiLab & @pauloslab) in biRxiv! @WinshipAtEmory @sitcancer .Clinically relevant orthotopic pancreatic cancer models for adoptive T cell therapy
biorxiv.org
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor. Prognosis is poor and survival is low in patients diagnosed with this disease; ∼12% at 5 years. Immunotherapy, including adoptive T...
0
2
20
RT @jessica_konen: Excited to announce that this manuscript is officially out in the latest issue of JCI! Thanks again to all the coauthors….
0
5
0
This! Please consider donating to our colleague in her time of need.
Friends and colleagues, our talented and hardworking technician, Soundharya needs your help! Please help us fundraise for her and her family in her time of need! .Share/donate! Any bit will help!.Fundraiser for Soundharya Kumaresan
0
0
1
RT @heykahn: If you're not using AI, you're falling behind. Here are 20 AI tools to future-proof yourself. Get more tools like this by si….
0
3K
0
☀️A must read by our MSTP student @GuillermoORang1! The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner.
biorxiv.org
Generating stem memory T cells (TSCM) is a key goal for improving cancer immunotherapy. Yet, the optimal way to modulate signaling pathways that enrich TSCM properties remains elusive. Here, we...
0
2
6
⭐️A must read!!! Congrats to @LesinskiLab & team for stellar work in novel immunotherapy to impact #PancreaticCancer. Just out in @JCI_insight: @sitcancer @ImmunologyAAI @WinshipAtEmory.
Our paper is out! Dual IL6/CTLA4 blockade in #PancreaticCancer so many collaborators over many years. @WinshipAtEmory @BwareRedHair @phillipsmaggiej @Chrystal_Paulos @hknochelmann @greeneEMnM @CarsonLabOSU @brobinsonGIpath @TMaceLab @cameron_herting @anruggieri @BasselElRayesMD.
0
0
6
We @PaulosLab honored to be #JITCTop10 for this coolio B cell ACT CD8 T cell paper. ;).
Countdown to 2023: #JITCTop10 - B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity @Aubrey_Smith04 @PaulosLab
0
1
38
CD40 agonism may circumvent a dysfunctional CD4 compartment to improve PD-1 blockade responsiveness, supporting a novel synergistic immunotherapeutic approach.
0
4
23
Increased numbers of neutrophils and macrophages associated with cancer progression may be risk factors for anaphylaxis.
0
0
2
The best of the best of the best, herein!! Woot @AyanaTRuffin.
#BIIW22 #BlackInImmunoRollCall.Hi there! I’m Ayana and I am a postdoc fellow in the @PaulosLab at @WinshipAtEmory . I am currently obsessed with B cells and their best friend CD4 T cells and how we might use both in adoptive cell therapy to treat cancer.
0
0
5
RT @Chrystal_Paulos: 💥Less is more: @MeganMWyatt’s new manuscript in @biorxivpreprint shows metabolically fit CAR T cells can be generated….
0
4
0
‘Wolde ye bothe eate your cake, and haue your cake?’.-John Heywood, 1546.Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy
pubmed.ncbi.nlm.nih.gov
Adoptive cellular immunotherapy (ACT) is a potentially curative therapy for patients with advanced cancer. Eradication of tumor in mouse models and humans correlates with both a high dose of adopti...
2
5
20
RT @Chrystal_Paulos: The @PaulosLab is VERY thrilled to welcome our #gamechanger postdoc fellow @AyanaTRuffin to @EmoryUniversity @….
0
3
0
RT @edyong209: … and an essay in the NYT. 7/
nytimes.com
The most familiar of settings can feel newly unfamiliar through the senses of other creatures.
0
19
0
RT @WinshipAtEmory: #ASCO22 | June 3 | Education Session | Developmental Therapeutics."Tebentafusp for Uveal Melanoma".Panel Speaker: Melin….
0
4
0