Zihai Li, MD, PhD
@Zihai
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Founding Director, Pelotonia Institute for Immuno-Oncology (@OhioStatePIIO) • Deputy Director of @OSUCCC_James for Translational Research • Views My Own
Columbus, OH
Joined July 2009
Are #NK_cells friends or foes in cancer #immunotherapy? We found they impede the development of anti-tumor NK-regulated T cells (#NKRTs). A separate study by @lab_marine showed that NK cells contribute to ICB resistance in melanoma.
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So proud of our students! Two major stories from my lab are on the way - each led by our amazing graduate students. Stay tuned. @OhioStatePIIO @OSUCCC_James.
🎉 Today is Graduate Student Welcome Day!. 👏 Thrilled to welcome new trainees in the.🎓 MS in #Immunology & Microbial Pathogenesis.🎓 PhD in Immunology & #Immunotherapeutics (I2GP). Looking forward to seeing these bright minds join our wonderful community of immunologists 🧬💡🛡️
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Generate videos in just a few seconds. Try Grok Imagine, free for a limited time.
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We’re wrapping up Strategic Plan 2.0 for @OhioStatePIIO. Stay tuned for what’s ahead! It’s remarkable to think 6 years have already passed since PIIO’s launch. So grateful to @pelotonia and the community to enable us to do impactful work.
pelotonia.org
Pelotonia is a community that is determined to see an end to cancer. Together, we've saved countless lives. Help us save more.
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The newly released research and funding priorities of @NIH
nih.gov
NIH is moving toward a unified strategy that aligns our priorities and funding approaches to fulfill this commitment.
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RT @YangZhao102: Excited to share our @Nature papers exploiting the receptor pairing code to expand the cytokine receptor alphabet in T cel….
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The law of protein folding - genetics, energetics, and allostery in proteins with randomized cores and surfaces
science.org
A lack of systematic experimental data limits our understanding of protein evolution. In this study, we experimentally characterized proteins with randomized sequences. Vast numbers of amino acid...
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The @NIH National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.
science.org
Republicans on spending committee push back against proposed reorganization and overhead cuts
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Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures
cell.com
A 50-year multi-tissue proteomic atlas reveals transcriptome-proteome decoupling, proteostasis decline with amyloid accumulation, and asynchronous aging clocks, identifying circulating senoproteins...
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RT @Chrystal_Paulos: BREAKING: We uncovered a potent immune alliance that could change how we treat solid tumors. Published in @Cancer_Cell….
cell.com
Cole et al. report that adoptively transferred, tumor-specific Th17 cells engage host B cells and drive B cell proliferation and differentiation. These Th17 cells require B cells for sustained...
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RT @KimrynRathmell: Inspired choices recognizing excellence in immunology all around!!! @JeffRathmell ❤️.
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AI or not, NIH limits scientists to six applications per year
science.org
Some critics of the new policy say the cap could hinder researchers in need of funding
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Yet another layer of complexity of NK cell biology and clinical translation.
Data suggest that eliminating NKG2D signaling could be beneficial in NK cell adoptive therapy, highlighting the need to better delineate downstream effects of NKG2D in humans rather than in mice before developing new #immunotherapy. Learn more:
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