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Avery Posey Profile
Avery Posey

@IAmDrDex

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Cancer Immunologist

Philadelphia, PA
Joined May 2011
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@IAmDrDex
Avery Posey
3 months
@PoseyLab PhD students Heather Sosnoski and Nohelly Derosiers delivered excellent oral presentations today at “Cellicon Valley ‘25: The Future of Cell & Gene Therapies”. Both were supported by the Muriel Joan Drew Hege MD fund (thx @KristenHege) and will present @ next week’s AAI
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@IAmDrDex
Avery Posey
5 months
The work of building a more inclusive STEM community is far from over. But it is a mission worth pursuing every day. We all have a role to play in making science equitable, accessible, and innovative for all. #BlackHistoryMonth #STEM #DiversityInScience #RepresentationMatters.
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@IAmDrDex
Avery Posey
5 months
Despite attempts to smear it, DEI is not a dirty acronym. It stands for anti-discrimination actions that create more representative environments of belonging. It also leads to better teams, stronger collaboration, & improved scientific outcomes.
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@IAmDrDex
Avery Posey
5 months
Scientific progress has historically been hindered by exclusionary & siloed practices. Diverse perspectives broaden discovery, challenge biases, & drive innovation. STEM doesn’t advance in isolation—it thrives when we uplift all voices.
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@IAmDrDex
Avery Posey
5 months
I stand on the shoulders of those who came before me. Their legacy reminds me that DEI isn’t just an ideal—it’s a responsibility. Progress isn’t linear. It must be actively upheld. Perseverance in one era lays the foundation for the next.
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@IAmDrDex
Avery Posey
5 months
His curiosity & love for discovery were contagious. He taught me that exploration—whether of the Earth, the universe, or the microscopic world of cells—is fundamental to progress. Now, I carry forward this generational passion as a scientist studying cancer & immunotherapy. 🧪🧬.
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@IAmDrDex
Avery Posey
5 months
Henson was also my grandfather’s cousin. His story had a profound impact on my family. Inspired by Henson’s legacy, my grandfather became a science educator, first in segregated & later in integrated schools, with a passion for earth science. 🌍.
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@IAmDrDex
Avery Posey
5 months
Henson was included in the historic journey, yet society’s embrace of inclusion is often conditional rather than consistent—in vogue one day, disregarded the next. #BlackHistoryMonth reminds us that representation in science has always been a struggle.
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@IAmDrDex
Avery Posey
5 months
His achievement came at a time when Jim Crow laws enforced segregation & discrimination, limiting opportunities for Black Americans in nearly every aspect of life. Yet, despite his accomplishments, Henson’s recognition was delayed until 1944—a reflection of systemic exclusion.
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@IAmDrDex
Avery Posey
5 months
Matthew Henson was a pioneer—an explorer who braved the harsh Arctic & played a pivotal role in the first expedition to the North Pole with Robert Peary in 1909. Some records even suggest Henson reached the Pole first. 🧊❄️ #BlackSTEM.
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@IAmDrDex
Avery Posey
5 months
🔬As we close this year’s #BlackHistoryMonth, I honor the legacies of those who persevered, innovated, and expanded human knowledge—despite the obstacles before them. A personal reflection on legacy, science, and the responsibility of diversity, equity, & inclusion (DEI). 🧵👇.
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@IAmDrDex
Avery Posey
6 months
Interestingly, this therapeutic approach runs counter to the lipid-lowering strategies that predominant CVD treatment. We are eager to now explore the efficacy of this therapy in models at risk for accelerated CVD, such as CHIP and checkpoint immunotherapy.
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@IAmDrDex
Avery Posey
6 months
This is the first demonstration that engineered immune cells can treat heart disease. And with these data, we are excited that CAR T cells may now be able to tackle heart disease in patients at high risk for plaque rupture.
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@IAmDrDex
Avery Posey
6 months
We developed CAR Tregs with specificity for OxLDL, and these cells remarkably reduced atherosclerosis in mice prone to the heart disease through immunosuppressive mechanisms. The Tregs suppress T cell proliferation, foam cell formation, and ~80% of plaque deposition.
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@IAmDrDex
Avery Posey
6 months
CAR T cells have shown efficacy in blood cancers and autoimmune disease. In my lab’s recent preprint, we developed CAR Tregs to tackle the #1 cause of human mortality - heart disease.
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biorxiv.org
Cardiovascular disease caused by atherosclerosis is responsible for 18 million deaths annually, highlighting a significant need for new medical therapies, especially for patients ineligible for...
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@IAmDrDex
Avery Posey
1 year
Many insights from this discussion - importantly, identifying biomarkers in your preclinical models that are indicators of drug activity are needed to improve clinical trial designs.
@jmancuso76
James J Mancuso, PhD
1 year
@IAmDrDex and Allison Institute Assistant member @sang_goswami chair an informative discussion on lessons learned from failed clinical trials at keystone meeting. Great insights from @AndreaCercek @aaparicioMD Hideho Okada and @ProfGLongMIA.
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@IAmDrDex
Avery Posey
1 year
RT @PennMedEVDCSO: Other exceptional @PennMedicine scientists recognized previously as part of the @CellCellPress #FacesofCell initiative i….
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@IAmDrDex
Avery Posey
2 years
As Dr. Susanna Greer, CSO of @TheVFoundation, recently wrote, I am an "all gas and no brakes" researcher! I am running the 2024 Chicago Marathon on Team V to raise funds supporting innovative cancer research! Read more and help support this cause at
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@IAmDrDex
Avery Posey
2 years
15 years ago, I stood in Grant Park for an event that changed the way I thought about democracy. What an event!.
@BarackObama
Barack Obama
2 years
15 years ago today, I asked you to believe in the change we could create together—and you did. I’m so proud of our Obama alumni, many of whom we saw this week, for carrying that mission forward.
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@IAmDrDex
Avery Posey
2 years
RT @ChelseaPinnix: Great talk and words of wisdom for undergraduate students from @AnthonyNguyenMD at the @sitcancer undergraduate in STEM….
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