KJWON_LAB
@KjwonL
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Computational Biology Lab at BRIC, University of Copenhagen
Copenhagen, Denmark
Joined July 2018
🔬Can whole-slide Hematoxylin and eosin (H&E) stained histology images predict gene expression profiles in single-cell spatial omics? #spatial #SingleCell Introduce our latest paper, BLEEP (Bi-modaL Embedding for Expression Prediction): a state-of-the-art tool predicting spatial
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Dinner & goodbye. The social side of science is what makes the difference. #singlecellCPH23 🌿 Vanessa Hall, Jeff Moffit, @adameykolab @KharchenkoLab @KhodosevichLab @KrishnaswamyLab @ravnskjaer_lab @AUGCsoup @KjwonL
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Nice safari into hundreds(instead of thousands) of cells to infer inductive interactions! Great work by @JunilKim_caleb and @MichaelaRothova who interrogated these critters in @KjwonL Shout out to collaborators: @IdoAmitLab @SiyeonRhee @rajangogna_ . https://t.co/DIr420GhI1
pnas.org
Development of multicellular organisms is orchestrated by persistent cell–cell communication between neighboring partners. Direct interaction betwe...
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Gene expression changes due to cell-contact with neighbors @pnas. Neighboring cell type prediction from #scRNAseq. Works by @JunilKim_caleb and Michaela. Collaboration with @josh_brickman, Rajan, and @IdoAmitLab. Thanks to @lundbeckfonden. https://t.co/7KFQlD6Q0x
pnas.org
Development of multicellular organisms is orchestrated by persistent cell–cell communication between neighboring partners. Direct interaction betwe...
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CFP: The Symposium on Artificial Intelligence for Learning Health Systems (SAIL) is a new annual conference on AI for clinical medicine. SAIL will be held in Puerto Rico on May 9-12, 2023. https://t.co/CXxjqvg8FH
#bioinformatics #artificialintelligence
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Gene regulatory network reconstruction from scRNAseq: Greatly reduced false positives using multivariate transfer entropy. Great work by Guangzheng and @JunilKim_caleb. Collaboration with @kedar_natarajan
https://t.co/bWVU2N2Vec
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In our new study we chart human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution (RNA + ATAC) @CellCellPress
https://t.co/jqTWLOZEIu
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We updated our database and now list 385 postdoc fellowship opportunities (w/ description, deadline, amount, eligibility, etc). Getting one means a lot more freedom to do the work you want to do.
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We have an open search for a collaborative biostatistician to join our faculty at @CedarsSinai! Please RT! https://t.co/AcrtJi0ZAT
#biostatistics #statstwitter #epitwitter #datascience
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It is great to see an algorithmic development (TENET) leads to finding a new factor important for autophagy. Great work by @JunilKim_caleb in collaboration with Sunghee Baek and Dongha Kim.
Systemic approaches using single cell transcriptome reveal that C/EBPγ regulates autophagy under amino acid starved condition
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scRNAseq analysis revealed the role for Shank3 neural stem cells and the association with autism. Collaboration with Jongphil Kim. https://t.co/5YC7P9zQvJ
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We (@KjwonL & @WennerbergLab )designed a tool for identifying and grouping effective drugs based on their response in multiparameter high-throughput and high-content screenings #cancer #AML #MDS #chemotherapy #immunotherapy
https://t.co/qHcH5eg6Za
@eLife
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Space-time analytics in digital human organoids! Stellar work from talents @WahlePhilipp @brangiov @HarmelChristoph @zhisong_he + team! Collab with @lucaspelkmans @TreutleinLab. Thanks @OrganoidAtlas @cziscience @humancellatlas @ETH_BSSE @IOB_ch #organoids
https://t.co/DxqNpmCLJ7
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A new type of analyzing spatial transcriptomics data.
Excited to announce our latest work in the @KjwonL Lab! We study cell contact-dependent gene expression using the transcriptome of spatial beads composed of multiple cell types. https://t.co/9tyWSxLA9Z
#SpatialTranscriptomics #SlideSeq #CellContact #CellCellInteractions
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What an exciting week for CUT&Tag!!! After we published spatial-CUT&Tag in Science last week, Prof. Xiaowei Zhang lab demonstrated combining CUT&Tag and MERFISH to image, for example, 127 target H3K4me3 loci or 139 H3K27ac loci in mouse brain. Very cool! https://t.co/BWddFt1Kdb
biorxiv.org
The recent development of spatial omics methods enables single-cell profiling of the transcriptome and the 3D genome organization in a spatially resolved manner. Expanding the repertoire of spatial...
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We’re excited to have this approach by @Morteza31846588 & @EllaKarjalainen published. A great collaboration with @KjwonL @HelinLab and the Grønbæk lab @UCPH_BRIC
@Morteza31846588 's work to process high-dimensional screening data is finally out in @eLife. It clusters samples based on their drug responses. Collaboration with @WennerbergLab.
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Spatial biology meeting organized by Oxford Global. Vesalius by @pcnmartin and @HyobinKim4 will be introduced. https://t.co/C110m2q5PN
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our paper is out: Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models
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Exciting preprint from @dana_peer lab on quantifying intestinal stem cell activity. Plus, interesting new deconvolution approach BayesPrism and pretty spatial visualization method SpaceFold. https://t.co/Zn6V2Tw7bY
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