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Bo Wang

@BoWang87

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SVP and Head of Biomedical AI @Xaira_Thera; Associate Prof @UofT; Chief AI Officer @UHN; former PHD, CS @Stanford; opinions my own. #AI #healthcare #biology

Toronto, Ontario
Joined September 2016
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@BoWang87
Bo Wang
2 days
Do deep generative models in single-cell omics really work for perturbation prediction?. Some benchmark studies say yes:.šŸ”— šŸ”—Others say no:.šŸ”— šŸ”— BMC Genomics: To move beyond this
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@BoWang87
Bo Wang
2 days
Really liked this meme from @lucascamillomd šŸ˜…
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@BoWang87
Bo Wang
2 days
Do deep generative models in single-cell omics really work for perturbation prediction?. Some benchmark studies say yes:.šŸ”— šŸ”—Others say no:.šŸ”— šŸ”— BMC Genomics: To move beyond this
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@BoWang87
Bo Wang
5 days
šŸš€ What do genomic Transformers actually learn about biology?.•What knowledge do they hold at random init, after pre‑training, and following fine‑tuning?.•We dove deep into every attention head to find out. šŸ“„ Preprint live now ā€œInterpreting Attention Mechanisms in Genomic
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@BoWang87
Bo Wang
7 days
Exciting day for the virtual cell revolution! šŸš€ . @arcinstitute has just launched the Virtual Cell Challenge, calling on leading institutions worldwide to push the boundaries in virtual cell modeling (. Huge congrats to Arc Team (@genophoria @pdhsu.
@arcinstitute
Arc Institute
7 days
Register today for the Virtual Cell Challenge and use AI to solve one of biology’s most complex problems. Announced in @CellCellPress, the competition is hosted by Arc Institute and sponsored by @nvidia, @10xGenomics, and @UltimaGenomics.
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@BoWang87
Bo Wang
8 days
What a mind-blowing week for AI in biology!. šŸš€ Xaira just dropped the largest genome-wide perturbation dataset ever last week. 🧬 Arc unveiled STATE yesterday, the most powerful foundation model for single-cell perturbation prediction. 🧠 DeepMind followed up with AlphaGenome,.
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@BoWang87
Bo Wang
13 days
More in-depth technical tweetorial from the amazing @_annhuang , the first author of our X-Atlas/Orion paper! .
@BoWang87
Bo Wang
16 days
šŸš€ Xaira Therapeutics has just dropped a game-changer for AI-driven biology. Today, we unveiled X-Atlas/Orion, the largest publicly available genome-wide Perturb-seq dataset to date—spanning 8.4 million single cells with perturbations across all ~20,000 human protein-coding
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@BoWang87
Bo Wang
13 days
My take?. It’s still early for AI models to accurately simulate biological processes. The bottleneck: lack of specialized, dynamic training data. But the potential is enormous—for science education, interactive textbooks, or even virtual cell simulation models.
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@BoWang87
Bo Wang
13 days
For comparison, here’s one of the best educational demos of the central dogma I’ve seen—made by humans, of course:. šŸ”—
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@BoWang87
Bo Wang
13 days
Next, I tried the latest @midjourney model, which supports video generation up to 5 seconds. Here’s what it came up with for the same prompt. šŸŽ„ā¬‡ļø
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@BoWang87
Bo Wang
13 days
First up: Google’s Veo 3 — arguably the most advanced video model right now. It supports up to 8 seconds of video generation. Here’s what Veo gave me for ā€œDNA to RNA to Protein.ā€.šŸŽ„ā¬‡ļø
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@BoWang87
Bo Wang
13 days
Prompt I used: "Generate an high-resolution animation video showing the central dogma of cellular biology, specifically how a DNA sequence is transcribed into RNA sequence, and how the RNA sequence is translated into protein sequence in a cell.".
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@BoWang87
Bo Wang
13 days
AI models for video generation are advancing fast. But how well can they capture biological processes?. I put them to the test using the most iconic concept in molecular biology:.The central dogma — DNA → RNA → Protein. Let’s see what the models produced 🧵
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@BoWang87
Bo Wang
13 days
Highly recommend! I’ve had the privilege of working with both @sara_mostafavi and @anshulkundaje when I was a student—they’re true pioneers in the field.
@anshulkundaje
Anshul Kundaje (anshulkundaje@bluesky)
14 days
@sara_mostafavi (@genentech ) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/
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@BoWang87
Bo Wang
15 days
If you're passionate about building the world's first AI virtual cell model, we're hiring at @Xaira_Thera-- come join us!.
@BoWang87
Bo Wang
16 days
šŸš€ Xaira Therapeutics has just dropped a game-changer for AI-driven biology. Today, we unveiled X-Atlas/Orion, the largest publicly available genome-wide Perturb-seq dataset to date—spanning 8.4 million single cells with perturbations across all ~20,000 human protein-coding
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@BoWang87
Bo Wang
16 days
RT @DeryaTR_: This is an incredible public dataset, 8.4 million single cells with 20,000 protein perturbations! Truly a game-changer for Bi….
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@BoWang87
Bo Wang
16 days
Got an email from my PhD student today—she had traveled to Tehran just a few weeks ago, right before war was unfolding. No complaints. No requests. Just a quiet, steady project update—sent with the kind of calm strength that left me speechless. I sat there staring at the.
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@BoWang87
Bo Wang
16 days
šŸš€ Xaira Therapeutics has just dropped a game-changer for AI-driven biology. Today, we unveiled X-Atlas/Orion, the largest publicly available genome-wide Perturb-seq dataset to date—spanning 8.4 million single cells with perturbations across all ~20,000 human protein-coding
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@BoWang87
Bo Wang
19 days
šŸ† Congratulations to nnInteractive (from German Cancer Research Center) and BioMedparse (from @Microsoft ) for taking the top prize in the CVPR 2025 Foundation Models for Interactive and text-guided 3D Biomedical Image Segmentation Challenge, respectively!. We curated 286K for
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@BoWang87
Bo Wang
20 days
Woke up to this kind message in my inbox and it truly made my day šŸ™šŸ„¹. As researchers, we often work long hours not knowing who might read or benefit from our papers. Seeing scGPT inspire others to build new models and push the field forward is one of the most meaningful
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