Lee, Jiyeon
@Jjiyeon_lee
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Research Professor/Ajou University Medical Center/WashU alumni/Circadian clock, Alzheimer's disease, lipids, REV-ERBs
Missouri, USA
Joined July 2019
Functional liver genomics identifies hepatokines promoting wasting in cancer cachexia: Cell
cell.com
Cancer-induced liver changes promote body wasting through secreted factors, with circadian regulators and hepatokines being important contributors to cancer cachexia.
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Cell-type-directed network-correcting combination therapy for Alzheimer’s disease: Cell
cell.com
A multi-cell-type drug discovery strategy targeting dysregulated gene networks in neurons and glia identified letrozole and irinotecan as a combination therapy that significantly improved memory and...
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RT @MolNeuro: '#Proteomic landscape of #AlzheimersDisease: emerging technologies, advances and insights (2021 – 2025)'. Jay M. Yarbro, Him….
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RT @davidasinclair: An antibody directed to the NAD-degrading enzyme CD38 in mice restores metabolic fitness, improves cognitive performanc….
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RT @SleepPIA: 🧠 Join us for an insightful discussion on Sex and Gender Differences in AD and Sleep/Circadian Rhythms!.🗓️ April 28, 10:00 AM….
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RT @CircadianClocks: This is the most important paper in the circadian field in over a decade. A completely new clock component that is ev….
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RT @mvlourenco: These are very interesting findings reporting astrocyte changes across Alzheimer's disease progression. It will definitely….
nature.com
Nature Neuroscience - Using single-nucleus RNA sequencing from 32 donors, researchers identified distinct astrocytic gene expression programs activated across brain regions and Alzheimer’s...
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RT @gabriel_tofani: 🚨 New Research. Excited to share my PhD work now published in @Cell_Metabolism.In this study we explore the role of the….
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RT @heniek_htw: Sex differences in sleep, circadian rhythms, and metabolism: Implications for precision medicine.ht….
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RT @SatchinPanda: Biological Age Vs. Chronological age is often discussed in academic and public discourse. This article in @NatureMedicine….
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RT @ShorterLab: Modeling Parkinson’s disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and pr….
nature.com
Nature Neuroscience - Bayati et al. discovered that sequential treatment of iPSC-derived dopaminergic neurons with α-synuclein fibrils and proinflammatory cytokines leads to the formation of...
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RT @CellCellPress: Now online! Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues
cell.com
Patho-DBiT enables spatial profiling of a range of RNA species (i.e., mRNA, microRNA, tRNA, splicing isoform, etc.) all at once in clinical formalin-fixed paraffin-embedded tissue with high sensiti...
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RT @LukensJohnR: Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy….
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RT @LukensJohnR: Gut-induced alpha-Synuclein and Tau propagation initiate Parkinson’s and Alzheimer’s disease co-pathology and behavior imp….
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RT @Cell_Metabolism: Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lacty….
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RT @SciencNews: Scientists should get paid for thinking time @Nature . #PhD #PhDlife #academics #AcademicChatter #AcademicTwitter #Postdocs….
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RT @ISMND1: We are thrilled to announce Dr. Eleanor Drummond @DrEleanorD @Sydney_Uni as our next ISMND Science webinar speaker!. Title: Usi….
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RT @LukensJohnR: Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease @NatureMedicine .h….
nature.com
Nature Medicine - APOE4-dependent neutrophil–microglia interactions drive cognitive impairment in female carriers with Alzheimer’s disease via IL-17F.
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RT @KnoblochLab: Excited and proud to see the final version of our manuscript out @NatureComms, describing a new….
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RT @ErikMusiek: Very excited that our astrocyte & microglia circadian atlas preprint is out! Congrats to @Patwsheehan on this awesome work,….
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