Muhammad Jbara
@JbaraM90
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Assistant Professor of Chemistry - TAU
Joined August 2017
שלושה חוקרים מאוניברסיטת תל אביב זכו במענקי ERC Starting Grant היוקרתיים לשנת 2025🏆 מועצת המחקר האירופית (ERC) פרסמה את תוצאות הקול הקורא של מענק ה- ERC Starting Grant לשנת 2025, בהם שלושה חוקרים מאוניברסיטת תל אביב. מענק זה מיועד לחוקרים וחוקרות מבטיחים בתחילת הקריירה האקדמית
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Thrilled that our #ProTailor project has been awarded the #ERCStG! With #ProTailor we will advance the development of synthetic transcription factors to crack the molecular mechanisms of gene expression and unlock exciting new applications! @ERC_Research
@TelAvivUni
#ERCStG
📣 The ERC Starting Grant call results are out! Find out which early-career researchers will receive funding, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025! ➡️ https://t.co/cGctMhcJos 🇪🇺 #HorizonEurope
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In 2025, the successful ERC Starting Grant applicants have 51 different nationalities and will carry out projects in 25 countries. This round of grants is estimated to create some 3,000 jobs within the teams of the new grantees. More facts and figures 👉 https://t.co/dVRIGSyi5T
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New preprint alert! We developed a covalent small molecule that targets guanines in structured RNAs, guided by the FMN riboswitch structure. In collaboration with Rob Batey https://t.co/3D52JDbUOQ
#RNA #DrugDiscovery #ChemicalBiology
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Despite all the sad moments back home, it was a great pleasure to receive the 2025 Vincent du Vigneaud Award during the APS meeting held in beautiful San Diego. Thank you to all the friends, colleagues, and past and present lab members who have been part of my scientific journey.
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Our latest preprint @ChemRxiv introduces a method for the Photocatalytic Late-Stage Decarboxylative Functionalization of Bioactive, Naturally Occurring, and Fatty Acids via gem-Borylsilyl Alkene. Congrats to @NadimEghbarieh 🏆 https://t.co/PBaU48CQ8H
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Our new preprint is out! We show how Au(III) organometallic chemistry platform can facilitate the formation of hybrid peptide tricycles, which are normally challenging structures to access. An Organometallic Chemistry Approach to Peptide Tricycles | ChemRxiv -
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Happy to share our new paper in @NatureSynthesis !! "In-brain synthesis of receptor-based protease sensors by coupling ligand-directed chemistry and click chemistry" https://t.co/ezdtP5s67a
nature.com
Nature Synthesis - The complexity of living systems makes methods for chemically functionalizing proteins in vivo rare. Here, a genetic-engineering-free method to modify receptor proteins with...
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Today, our new study titled “Cell-Based Assay of Pd-Mediated Arylation of Cyclic Peptide Binders of Ubiquitin Chains: Towards Modulating NEMO Liquid-Liquid Phase Separation” was published in ChemRxiv https://t.co/dnGWBF7kdO
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Truly honored to have been selected as a JSP Fellow at the 58th Bürgenstock Conference 2025. Thanks, @SwissChemistry and the organizers for an incredible and inspiring week in Brunnen! #SCS_BC25
https://t.co/zsshLOCnSm
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JSP program at the Bürgenstock conference 2025 promotes Scientific Leaders of the next Generation from both academia and industry! Class 2025 JSP together with the Bürgenstock president José Luis Mascareñas. #SCS_BC25 #JSPFellow2025 #scs
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Eid Mubarak! We are happy to share our latest work @JOC_OL on Programmable Strategies for the Conversion of Aldehydes to Unsymmetrical (Deuterated) Diarylmethanes and Diarylketones | Organic Letters https://t.co/hbBtDGQGMX Congrats to @vipingavit8 ,Nicole , @NadimEghbarieh
pubs.acs.org
Herein, we present a versatile method for synthesizing unsymmetrical diarylmethanes and diarylketones from aldehydes and arenes. This involves: (1) regioselective Ar–H alkylation to form benzhydryl...
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"One-Pot Total Synthesis of a Post-translationally Modified Max Transcription Factor Sheds Light on Ser-Phosphorylation and Lys-Acetylation Crosstalk in DNA Binding" Raj V. Nithun, Shada Khoury, and Muhammad Jbara https://t.co/JTbihozCP8
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One-Pot Total Synthesis of Post-translationally Modified Max Transcription Factor in Seven Consecutive Steps: Unveiling the Crosstalk Between Ser-Phosphorylation and Lys-Acetylation in DNA Binding | Published @JOC_OL
https://t.co/HXCI6tu3Lq Congratulations to Nithun and Shada!
pubs.acs.org
We report a one-pot total synthesis of the transcription factor Max in seven consecutive steps, starting from three peptide segments and employing native chemical ligation. The developed synthesis...
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Several years in the making: we show how exopolyhedral substituents on a symmetrical dodecaborate cluster result in a perfect electronic directing effect and vertex-precise functionalization. Carboranes without Cage Carbons: closo-Dodecaborate Mimics of Neutral closo-Carboranes |
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Our feature article in @ChemCommun’s #2025PioneeringInvestigators special issue on structurally constrained, cationic P(III) species is now online! It highlights a lot of our work in the field. Congrats to @Deependrabawari & @DoniaToami99! https://t.co/5PBG9CDAuX
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Thrilled to share our latest work: Abiotic Transcription Factors by Strategic Insertion of Non-Proteinogenic Amino Acids. Appeared today on @ChemRxiv
https://t.co/jMgfQD6jkF Exciting collaboration with @dynafluors & @Afek7Afek Congrats to Omer, Ferran, and the rest of the team!
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Ligand-Enabled Selective Coupling of MIDA Boronates to Dehydroalanine-Containing Peptides and Proteins | Journal of the American Chemical Society @NUS @UTokyo_News_en @TotalSyntheses
pubs.acs.org
α,β-dehydroalanine (ΔAla) is a uniquely reactive nonproteinogenic amino acid often employed for the late-stage functionalization of peptides, natural products (NPs), and proteins. The modification of...
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Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody–Drug Conjugates | Journal of the American Chemical Society @EdinburghUni
pubs.acs.org
Antibody–drug conjugates (ADCs) represent promising therapeutic constructs to enhance the selective delivery of drugs to target cells; however, attaining precise control over the timing and location...
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