Andy Intlekofer
@IntlekoferLab
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Physician scientist in HOPP and DOM/Lymphoma at Memorial Sloan Kettering. Our lab studies the metabolic control of cell fate and oncogenesis. Tweets are my own.
New York, NY
Joined May 2014
It was an honor to be part of this team effort to understand how some cancers develop resistance to IDH inhibitors. Thank you Alan Shih, Eytan Stein, Craig Thompson, and Ross Levine! @rosslevinemd @sloan_kettering #mskcc
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Excited to share our collaboration w/ @bradleybio demonstrating that pharmacologic modulation of splicing induces immunogenic neoantigens and augments response to checkpoint blockade. Jointly led by @SXLuLab, @ejdeneef, @jdthomaslab. Out today in @Cell: https://t.co/kKWVNjnv9C
cell.com
By provoking production of “neoantigens” that are recognized by immune cells, drugs that modulate RNA splicing can enhance cancer immunotherapy.
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So proud that the first paper from @VardhanaLab, an equal collaboration with @Ron_cology and Alex Huang's lab, is out today in @NatureMedicine: https://t.co/kQGH0haNZO. I posted a long tweetorial about this study when it was a preprint, but a few additional thoughts:
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Please read and use our latest work with @CompProteomics on agnostic chemical proteomics: Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics
pubs.acs.org
Recent studies have revealed diverse amino acid, post-translational, and noncanonical modifications of proteins in diverse organisms and tissues. However, their unbiased detection and analysis remain...
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Congrats to @SylviaZohrabian and @IntlekoferLab ! @WeillCornellGS and #WCGSBCMB directors are so pleased ! Yay! Keep the good news coming!
Congratulations to my very first graduate student @SylviaZohrabian for receiving the @DeptofDefense Horizon Award! A welcome piece of good news in a difficult year. @WeillCornellGS @sloan_kettering. Meet Our 2021 Fellows...
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Congratulations to my very first graduate student @SylviaZohrabian for receiving the @DeptofDefense Horizon Award! A welcome piece of good news in a difficult year. @WeillCornellGS @sloan_kettering. Meet Our 2021 Fellows...
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#CancerCare can’t wait. If you or someone you know has symptoms or has been diagnosed with cancer, please don’t wait. The #cancer experts at Memorial Sloan Kettering are here for you. Connect with an MSK cancer expert. https://t.co/PKGFgwD3Xi
#MSKAlways
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For all aspiring cancer researchers, check out the PhD program @GSKGradSchool @sloan_kettering. It’s an amazing and supportive environment to train in!
Learn more about our #PhD program in #Cancer #Biology and #BiomedicalSciences by joining a virtual information session. Hear from our Deans and students about the innovative program embedded within @sloan_kettering in #NYC. Register on our webpage https://t.co/PWCmDEIQwh
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Learn more about our #PhD program in #Cancer #Biology and #BiomedicalSciences by joining a virtual information session. Hear from our Deans and students about the innovative program embedded within @sloan_kettering in #NYC. Register on our webpage https://t.co/PWCmDEIQwh
sloankettering.edu
The Gerstner Sloan Kettering Graduate School of Biomedical Sciences offers the next generation of basic scientists a program to study the biological sciences through the lens of cancer
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New Review online! T Nielsen &co discuss how the disease biology of many sarcomas is driven by #chromatin pathway alterations w/ a view to use this knowledge to better develop targeted therapies for patients with #sarcoma. https://t.co/nSf5BM360k
@NatResCancer #DNAmethylation
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Check out @mluzsoula new paper on metabolic determinants of lipid peroxidation. An equal collaboration between our lab (Ross Weber and @JaviGBermudez) and @PrattGroup
https://t.co/o9ApIWdyPJ
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I am pleased to share our paper out today in @Cancer_Cell identifying a novel cancer cell state that is central to phenotypic transitions - and that seems to play a key role in tumor progression and drug resistance.
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Congratulations to @IntlekoferLab fellow Zach Epstein-Peterson (@zde_p) for receiving the 2020 @AACR @AstraZeneca Lymphoma Research Fellowship! Excited to see the impactful discoveries you will make @sloan_kettering.
aacr.org
Since 1993, the AACR has allocated more than $460 million and awarded over 800 grants to support thousands of scientists devoted to advancing the understanding, prevention, diagnosis, and treatment...
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I am so excited that our paper exploring how metabolic dysfunction contributes to T-cell exhaustion is out today in @NatImmunol. A thread (1/X):
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MSKCC is offering a free virtual seminar series for High School Students. We welcome all interested to attend - visit our website for registration information. @CharlesSawyers @rosslevinemd @wolchokj @ederlinda @IntlekoferLab
@DSolit @MFBerger1 @CDebyaniPhD
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Today's DF/HCC @LLSusa #ConnectScience #Webinar at 12: TALK 1 @TothovaLab: Biology and Therapeutics Targeting of #CohesinMutations in #MyeloidMalignancies TALK 2 @IntlekoferLab @sloan_kettering: Oncogenic Mechanisms and Therapeutic Targeting of 2-Hydroxyglutarate Metabolism
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Today's DF/HCC @LLSusa #ConnectScience #Webinar at 12pm: David Tuveson @CSHL, "Pathways of Progression in #PancreaticCancer" Next wk: M: Douglas Hanahan @EPFL Tu: @TothovaLab @DanaFarber Tu: @IntlekoferLab @sloan_kettering Th: @DrTonyLetai @theSFPM @DanaFarber
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