Kivanc Birsoy
@KivancBirsoy
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Associate Professor at the Rockefeller University
Manhattan, NY
Joined April 2018
How does mitochondria sense and control their glutathione levels? Our new work @ScienceMagazine by a fantastic student @YuyangLiu1996 describing a redox metabolite sensing mechanism for mitochondria. @RockefellerUniv @TheMarkFdn
science.org
Blockage of an inner mitochondrial membrane protease stabilizes a glutathione transporter, enabling autoregulatory homeostasis.
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Our new work in @Cell_Metabolism by @ArtemAKhan describes three new SLC transporters, including SLC25A45, a mitochondrial transporter for methylated amino acids that is essential for carnitine synthesis and fasting adaptation. @RockefellerUniv
cell.com
Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as a key mediator of mitochondrial...
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Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @Cell_Metabolism @RockefellerUniv
cell.com
Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as a key mediator of mitochondrial...
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Applications for faculty positions at Rockefeller are now open! We are seeking exceptional, creative scientists to join our faculty. Learn more below: https://t.co/EVtKiEgNBf
rockefeller.edu
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We are deeply saddened to share that our friend and colleague Jim Hudspeth passed away on Saturday. We will remember and continue to be inspired by Jim’s integrity, his humility, and his unwavering commitment to discovery.
rockefeller.edu
A. James Hudspeth, a Rockefeller neuroscientist who discovered how sound waves are converted into electrical signals in the ear’s cochlea, died Saturday at his home in Manhattan. A pioneering...
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Mitochondrial GSH is essential for metastasis due to it function in signaling and iron homeostasis. We are grateful for the support of @TheMarkFdn and @theNCI for this project. Also thanks to many collaborators @RichPossemato @Aslan_Tasdogan
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New work from our lab describing a role for mitochondrial glutathione in breast cancer metastasis @nicoledelgaudio @RockefellerUniv
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Congrats @JaviGBermudez for this well deserved honor! Looking forward to many discoveries from your lab!
Honored to be named a 2025 Pew-Stewart Scholar for Cancer Research. Grateful for the support and excited for the science ahead! https://t.co/sDlJRZ4YHA
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Congratulations @TimCKenny for your new position! Looking forward to many discoveries in your lab at @IcahnMountSinai !
Thrilled to announce that I will be joining the Cardiovascular Research Institute at @IcahnMountSinai as an Assistant Professor in January! My laboratory will focus on nutrient transport and cellular metabolism in physiology and disease.
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Congrats @JaviGBermudez lab on this fantastic discovery! So well deserved!!! This needs to be considered for future ferroptosis work in vivo.
My lab's first paper is out in @Nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering the lipid antioxidant α-tocopherol. Surprisingly, tumors use sulfated glycosaminoglycans—not canonical receptors—to capture lipoproteins.
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#CSMetabolites2025: Explore the latest on Metabolites: Organellar communication in health & disease. May 11–13, 2025, in Sitges, Spain! Registration discount deadline next week—don’t miss your chance to save! Register now: https://t.co/PQrs436S1w
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Join @CellSymposia #CSMetabolites2025, May 11–13, 2025, in Sitges, Spain—featuring Lulu Cambronne (@LACambronne, @UTAustin) on localized real-time sensors for metabolic signaling. Register by March 28 to save! https://t.co/OEcaL9MAip
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Register now for @CellSymposia #CSMetabolites2025, May 11–13, 2025, in Sitges, Spain! Explore cutting-edge research with world-class experts in a stunning location. Early registration discount deadline: March 28! https://t.co/HN4JnK3LC8
#CSMetabolites2025
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Excited to share our perspective on solute carrier transporters - gatekeepers of metabolism https://t.co/jWB44CnMhR
@KivancBirsoy @YuyangLiu1996 @gadmark @TimCKenny @CellCellPress @RockefellerUniv
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Last Chance! Deadline Today! Don’t miss your opportunity to submit an abstract for @CellSymposia Metabolites: Organellar Communication in Health and Disease, May 11–13, 2025, in Sitges, Spain. #CSMetabolites2025 Submit now: https://t.co/1sTsbgsxHS
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I'm excited to be co-organizing a Cell Symposia on metabolites in organellar communication with @KivancBirsoy, @RobertoZoncu, and @metabolism_ally (@Cell_Metabolism). The abstract deadline is Feb 14. I hope to see you in Spain!
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REVIEW | @KivancBirsoy, @abu_remaileh and colleagues (@RockefellerUniv, @Stanford) The authors provide a broad overview of the fundamental aspects of #choline #metabolism and cellular handling, and how it impacts physiology and pathology Read it here: https://t.co/5HXK9TTH2A
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Beautiful story by @SohailTavazoie describing a genetic basis for metastasis. @RockefellerUniv
A commonly inherited genetic variant of human PCSK9 drives breast cancer metastasis and associates with reduced patient survival. @CellCellPress PCSK9 drives pro-metastatic genes by repressing LRP1. Anti-PCSK9 antibody has breast CA metastasis suppressive effects
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Congratulations to @statnews Wunderkind @mluzsoula for this recognition! @RockefellerUniv
https://t.co/Jc9K4OHt1m
statnews.com
This cancer and metabolism researcher says the only limit as ‘yourself’ Ahmed Ahmed blends public policy with medicine to learn about the healthcare workforce. Read his story.
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Congrats @JaviGBermudez for this well deserved recognition!
Grateful to receive the NIH Director’s New Innovator Award #NIHHighRisk Congratulations to all the amazing investigators in this cohort.
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