Tobias Bald
@Doc_Bald
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I am a tumor biologist and immunologist studying the phenotypic plasticity of cells in the tumor microenvironment.
Bonn, Germany
Joined April 2018
In three Phase III trials (mUC: IMvigor211, mRCC: IMmotion151, NSCLC: OAK) immunotherapy prolonged OS when baseline serum albumin was >35g/L -> Prediction of less immune fitness via simple albumin measurement? https://t.co/NVAyxJznOH
@OncoAlert @ClinTransImmuno @Doc_Bald @IEO_Bonn
onlinelibrary.wiley.com
We show in 3 different randomized trials, that serum albumin is a strong predictor of survival in patients with cancer treated with atezolizumab. The predictive value of serum albumin is independent...
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Excellent presentation by Gonzalo at the Single Domain Antibodies Meeting 2023 in Paris on his generic #CRISPR #CAR T cell platform! Important tool to improve #cellular #cancer #immunotherapies @UniBonn @ImmunoSens @MSSOabcd @IEO_GloddeLab
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Happy to share our work: Integrating On-Treatment Modified Glasgow Prognostic Score and Imaging to Predict Response and Outcomes in Metastatic Renal Cell Carcinoma @JAMAOnc. See our tweetorial and the terrific editorial by @ggebraelmd @GliceidaGalarza @neerajaiims @urotoday 1/7
Integrating on-treatment mGPS (CRP + albumin) for a more holistic and patient-centered therapy monitoring in addition to radiological staging may improve outcome prediction for patients with mRCC. @saal_jonas @niklas_kluemper @IEO_HolzelLab @UniklinikBonn
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After 5 days of #science and networking, the ImmunoSensation2 SummerSchool "#Immunology at scales" comes to an end. We hope everyone had a great time at Schwanenwerda #Abendsonne 😉 Also want to be a #PhD #Student @ImmunoSens? 👉 https://t.co/leRMZs6aLN
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Well done Fenna!!! You are a fantastic PhD student keep up with the good science! Thanks @UniBonn, @UniMelb and @BonnMelbPhD for this great Retreat!
Final day of our retreat: big thanks to Andreas @DrAndy92 & Abdalla @abdalla42353282 for sharing their experiences with the joint PhD @UniMelb @UniBonn & congratulations to Fenna Feenstra @IEO_baldlab & Helena @HelenaHorvatic for receiving our awards for the best talk/ poster 🏆
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Longitudinal CRP kinetics (CRP Flare :fire:) predicts immunotherapy response within the first month in NSCLC! Great tool for therapy monitoring and as an integral biomarker for biomarker-directed study design @niklas_kluemper @Doc_Bald @IEO_BaldLab @IEO_Bonn @ImmunoSens @UniBonn
New #JITC short report: C reactive protein flare predicts response to checkpoint inhibitor treatment in non-small cell lung cancer https://t.co/gzRGgwLi74
@niklas_kluemper @Doc_Bald
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Longitudinal CRP kinetics (CRP Flare 🔥) predicts immunotherapy response within the first month in NSCLC! Great tool for therapy monitoring and as an integral biomarker for biomarker-directed study design @niklas_kluemper @Doc_Bald @IEO_BaldLab @IEO_Bonn @ImmunoSens @UniBonn
CRP flare 🔥! Longitudinal CRP kinetics predicts response to immunotherapy in NSCLC as early as 4 weeks after therapy start. Simple on-treatment biomarker to optimize monitoring. Chance for early therapy adjustments. Thanks to all collaborators! @docbald @IEO_HolzelLab @UniBonn
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We are excited to welcome Prof Tobias Bald @IEO_baldlab @UniBonn & Prof @MarcoHerold_J @WEHI_research @UniMelbMDHS as new PIs to our program! DFG funding @dfg_public for their project investigating CD155-CD226 interactions for T cell functionality in cancer has been approved 🥳
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CRP as biomarker to predict responses to immune checkpoint inhibitors in patients with metastatic renal cancer. Great potential for the clinic as simple and cost-effective. Congrats to @niklas_kluemper @UniklinikBonn and collaborators. https://t.co/2qFdb8c9dX
onlinelibrary.wiley.com
In this multicentre study, we investigated the predictive potential of early serum C-reactive protein (CRP) kinetics during 1st-line immunotherapy in metastatic renal cell carcinoma (mRCC). Out of...
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New paper published by Klümper et al. about CRP as a biomarker in metastatic renal cancer. Congratulations to all collaborators🎉@niklas_kluemper
CRP as biomarker to predict responses to immune checkpoint inhibitors in patients with metastatic renal cancer. Great potential for the clinic as simple and cost-effective. Congrats to @niklas_kluemper @UniklinikBonn and collaborators. https://t.co/2qFdb8c9dX
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🥳Attention science enthusiasts🥳We are excited to announce the launch of our new IEO website. Check it out to find out more about our research and spread the word 🎉 https://t.co/uNcbhG9ORd
@ImmunoSens @HCM_Bonn @UniklinikBonn @UniBonn
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Dieser Text von Paul Offit, dem führenden Kinder Impfspezialisten in den USA, erklärt überzeugend, weshalb auch Kinder im Alter 5-12 J geimpft werden sollten. Sehr lesenswert. Den Impfstoff werden wir bald auch in Deutschland haben, ich schätze vor Weihnachten
The compelling case for vaccination in kids https://t.co/NZgNxqNbP1
@ScienceMagazine "Vaccinating all children against SARS-CoV-2 could be among the most impactful public health efforts the US has seen in decades."
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We are happy to share the most recent publication from our Institute by PhD student @InesKalt describing Hip Kinases as a target of the FDA approved cancer drug Abemaciclib. Read the full article in @NatureComms here:
nature.com
Nature Communications - Abemaciclib is a third generation CDK-directed drug used in the treatment of HR + /HER2 negative advanced or metastatic breast cancer. Here the authors...
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👏Congratulations to @Doc_Bald for recieving the Lisec-Artz Prize, together with Sebastian Kobold! Well deserved! @UniBonn @UniklinikBonn @IEO_baldlab
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LAMP-Seq with 1-enzyme protocol out today https://t.co/MmBETJk5fN, grateful to colleagues @ Bonn&Boston! @k_u_ludwig @RSchmithausen @_David_Li @ronhollstein @biomiko @NIshorst @LMHighfield @evabeins @InesKalt @MaxSticks7 @ern_esth @jacobborrajo @thestrecker @HolzelMichael @zhangf
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Absolutely thrilled to see this work finally published! About 15 months ago I started on a journey which I could not have imagined before… Interested in the story behind the scenes? My first-ever thread. 1/n
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding https://t.co/ng1ncABjGV
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🚨 JOB ALERTS 🚨 We are hiring! Fully funded PhD and Postdoc positions available! Come work with us! @LabSchultze Great team, infrastructure and scientific environment! 🗓️ Apply until April 30!
📢 We have several open, fully funded positions in our group!! 📢 You are a wet lab scientist, computational biologist or data scientist interested to study human immunology with systems approaches? Join our interdisciplinary team in the beautiful city of Bonn!
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Check out new @GrasLab study on SARS-CoV-2 CD8+ T cell response. Well done to co-first authors @Emma_J_Grant and Dimitra from @GrasLab and Katie Lineburg & Srividhya Swaminathan from @QIMRBerghofer
Our study on SARS-CoV-2 CD8+ T cell response is now online @ImmunityCP. Thanks to the fantastic collaboration between @MonashBDI @LIMSLTU @latrobe @QIMRBerghofer @UQMedicine @ANSTO @uwanews with Corey Smith and @K_RenfreeShort and everyone involved 👏 https://t.co/gXLNxxOT8T
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