IEO_HölzelLab
@IEO_HolzelLab
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Hölzel Lab, Institute of Experimental Oncology, Tumor Microenvironment and Cancer Immunotherapy, University Hospital Bonn. @UniBonn @UniklinikBonn @ImmunoSens
Bonn, Germany
Joined December 2019
Pleased to share our latest work demonstrating how the choice of target antigens for adoptive #Tcell therapy determines #melanoma resistance mechanisms. Check out @ImmunityCP for details. 1/13 https://t.co/0kdNJbYDl1
cell.com
Using mouse models of melanoma, Effern et al. demonstrate how the choice of target antigens for adoptive T cell therapy determines resistance mechanisms. Targeting melanosomal antigens promotes...
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Day 4 of the fantastic @BonnMelbPhD retreat in beautiful Lorne @UniBonn @TheDohertyInst @UniMelbMDHS @WEHI_research @ONJCRI @Hudson_Research
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Exciting study reveals correlation between Trop2 target expression and anti-Trop2 ADC SG response in TNBC! @JCO_ASCO @ASCOPost @PTarantinoMD Membranous target gene expression crucial for ADC efficacy! ➡️ well-established for Her2, Nectin4, and Folr1 ! We need to consider the
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We are excited that our latest study on cDC1-mediated coordination of anti-cancer responses by tumor-infiltrating TCF1+stem-like CD8+ T cells, led by @PhilippaMeiser is now published OPEN ACCESS in @Cancer_Cell! https://t.co/HRLzKv6QDs 🧵👇1/n
cell.com
Mechanisms that determine dysfunctional versus protective anti-cancer immunity remain enigmatic. Meiser et al. reveal that a distinct population of immunostimulatory CCR7neg cDC1 in tumors provides...
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Great news in #Tumor #Immunology #research: https://t.co/J5aYDJKEt4 "InterpreTME" recieves funding by @BMBF_Bund to develop new AI tools to analyse the tumor microinvironment. Congratulations to our members @ThurleyLab @IEO_HolzelLab @JanHasenauer and Alexander Effland!
immunosensation.de
The success of cancer treatment depends not only on the type of tumor, but also on the surrounding tissue. Tumors influence it to their advantage, promoting…
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CRP as biomarker to predict responses to immune checkpoint inhibitors in patients with metastatic renal cancer. Great potential for the clinic as simple and cost-effective. Congrats to @niklas_kluemper @UniklinikBonn and collaborators. https://t.co/2qFdb8c9dX
onlinelibrary.wiley.com
In this multicentre study, we investigated the predictive potential of early serum C-reactive protein (CRP) kinetics during 1st-line immunotherapy in metastatic renal cell carcinoma (mRCC). Out of...
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🥳Attention science enthusiasts🥳We are excited to announce the launch of our new IEO website. Check it out to find out more about our research and spread the word 🎉 https://t.co/uNcbhG9ORd
@ImmunoSens @HCM_Bonn @UniklinikBonn @UniBonn
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Exploring the family center of @ImmunoSens with @norabalzer1! We were pretty impressed as it's equipment can also entertain adults!😅😆🥰 Happy to be part of a system where people with children feel supported and welcome! Well done!
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The IEO at the #clustersciencedays 2021 🥳 Join us at our poster booths and online poster sessions😊 @ImmunoSens @UniBonn
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Congratulations Dr. Niklas Klümper @niklas_kluemper 🥳 Great achievement!
#Urologie am #UKBonn forscht zu #Immuntherapie bei #Nierenkrebs: Dr. Niklas Klümper gewinnt ersten Vortragspreis für experimentelle Forschung auf dem weltweit größten Urologenkongress 2021. #Nierenzellkarzinom #Spitzenmedizin
https://t.co/MCz1ZVaMaK
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Congratulations, @susanna_s_ng! Werner-Müller prize 2021 for your great PhD work on NKG7 published in @NatImmunol. The @IEO_HolzelLab is proud that you have joined our lab at @ImmunoSens @UniBonn. More exciting findings on cytotoxic immune cells to come!
We are pleased to announce the winner 🥳👏 of the Werner Müller Prize 2021: Dr. Susanna Ng @susanna_s_ng .She is honored for her outstanding work on the role of Natural Killer Cell Granule Protein 7 in the immune response directed against malaria and leishmania
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Are you interested in finding out about exciting research opportunities? Then check this out 👇 and join the Immunosensation Roadshow on October 5th!
You are a postdoc or PhD student? The #ImmuneSystem is your scientific passion? You want to go abroad? Then join us for our Immunosensation Roadshow on October 5th! #postdocposition @UniBonn
https://t.co/smGT8l9Fqh Immunosensation2 Roadshow https://t.co/sWD9s0KouW via @YouTube
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We are recruiting for our 3rd student cohort @UniBonn @UniMelb - spread the word! More information: 👉 https://t.co/MhpDOfECJG
#PhDjobs @dfg_public @UniklinikBonn
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This is HUGE! … and tiny! Pre-print of the institute @IsbBonn describing the structure of the NLRP3 decamer just online. On top of that we see the inhibitor CRID3 binding to NLRP3. Read the whole story here:
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LAMP-Seq with 1-enzyme protocol out today https://t.co/MmBETJk5fN, grateful to colleagues @ Bonn&Boston! @k_u_ludwig @RSchmithausen @_David_Li @ronhollstein @biomiko @NIshorst @LMHighfield @evabeins @InesKalt @MaxSticks7 @ern_esth @jacobborrajo @thestrecker @HolzelMichael @zhangf
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Absolutely thrilled to see this work finally published! About 15 months ago I started on a journey which I could not have imagined before… Interested in the story behind the scenes? My first-ever thread. 1/n
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding https://t.co/ng1ncABjGV
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Currently looking for a job as an RA? Then check out this interesting opportunity👇 @UniklinikBonn @IEO_baldlab
🚨 YAHOO! WE ARE RECRUITING~!🚨 Ready to be part of our awesome pawsome team? We have an open RA position right here in UKB! Head over to https://t.co/UhVi0VFnu7 to find out more! We look forward to meeting you soon! Till then, bis später!
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Join our screening event of "Picture a scientist" @PictureaSciFilm between July 4th - July 5th. For more info see below 👇and register here: https://t.co/RIYoF4vXj9
@BonnMelbPhD @trr259 @237Crc
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Proud to see our work on #epigenetic regulation of #immune signaling in #neuroblastoma online @jitcancer. Great team effort by Johanna, Julia, Kritika, Susanna, Julian and Dillon. Nice collaboration between @UniklinikBonn @UKKoeln @UniklinikEssen #NRW
https://t.co/BFDNMJJ2pt
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We're proud to advertise the @pintofscienceDE #pint21 (May 17-19), which is co-organized by our alumni @MaikeEffern and there will be talks by scientists from Bonn @UniBonn Check out the program 👇or https://t.co/5iTcBqFySd
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Next up we have our 1st year student Lewis in the Gebhardt lab @UniMelb & @HolzelMichael lab @UniBonn. Lewis currently explores the mechanisms of the immune system that control melanoma in 🇦🇺and is hoping to travel to 🇩🇪 in 2022🤞
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