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David Sher

@DavidSherMD

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"Ultimately, the secret of quality is love. You have to love your patient, you to have to love your profession, you have to love your G-d." Avedis Donabedian

Dallas, TX
Joined April 2019
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@DavidSherMD
David Sher
2 days
RT @DrMLChua: This is BIG in the literal sense…. Massive effort bringing together FIFTY #HeadNeckCancer experts to debate and share their c….
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@DavidSherMD
David Sher
3 days
This paper is a nice addition to the literature on the successful use of carboplatin-paclitaxel as a radiation sensitizer. The favorable results clearly motivate larger prospective trials on the use of carbo-pac as a radiation sensitizer in HNSCC. The most commonly delivered.
@JAMAOto
JAMA Otolaryngology – Head & Neck Surgery
3 days
In patients with SCCHN receiving radiation with C/P vs cisplatin, there were no differences in locoregional recurrence-free survival, progression-free survival, distant metastasis-free survival, and overall survival. @DRNabilSaba @NikkiSchmittMD
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@DavidSherMD
David Sher
4 days
RT @hncalliance: There’s something powerful about being in a room with others who truly understand. We’d love to see you in person in LA on….
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@DavidSherMD
David Sher
4 days
This guideline is an excellent document, not only with respect to the different variations of case presentations but also the thoughtful discussions. I am still perplexed by the avoidance of IMRT in this disease. It provides superior dosimetry, not just for the carotids but.
@JAMAOto
JAMA Otolaryngology – Head & Neck Surgery
5 days
More than 12 000 new cases of laryngeal #cancer are diagnosed annually in the US. This Review summarizes the American Radium Society's guidelines on early glottic cancer management. @MCWardMD
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@DavidSherMD
David Sher
5 days
RT @UTSW_RadOnc: Join us for the second PULSAR Consortium Meeting at @ASTRO_org on Monday, September 29, at 6 p.m! This special meeting wil….
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@DavidSherMD
David Sher
6 days
RT @SameerKeoleMD: @DavidSherMD 💯 . The Clinical Trials Session is loaded too. @DrSpratticus will present NRG GU006 and I think it’s goin….
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@DavidSherMD
David Sher
6 days
This plenary session will be AWESOME.
@SameerKeoleMD
Sameer Keole
8 days
Plenary at the @ASTRO_org AM is stacked with 5 phase III studies. 🔹 Breast: RADCOMP (proton vs photon).🔹 H&N: TORPEdo (proton vs IMRT, Europe).🔹 Prostate: NRG GU005.🔹 Bladder: BART from @TMCIndia.🔹 Brain mets: METIS (RT +/- TTF)
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@DavidSherMD
David Sher
20 days
Very useful data. Now, it's time to generalize these conclusions to the unknown primary diagnostic work-up. The likelihood that a contralateral tonsil cancer generated the malignant adenopathy is too trivial to warrant bilateral tonsillectomies to find the primary, and.
@JAMAOto
JAMA Otolaryngology – Head & Neck Surgery
20 days
Systematic review and meta-analysis: Omitting contralateral elective extracapsular tonsillectomy in tonsillar SCCa is safe, with low metachronous contralateral second primary tumor rates and no difference in survival outcomes. @andrewpete_
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@DavidSherMD
David Sher
23 days
RT @jryckman3: @DavidSherMD The whole 3D vs. IMRT debate feels like a uniquely American pastime.
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@DavidSherMD
David Sher
23 days
The 4-Field was a CC Wang/MGH technique to improve conformality in the 2D-3D era. It's my go-to if treating the whole larynx but IMRT is denied. Clearly better than laterals but still worse than IMRT. I can't wait for when we can talk about involved/single-cord treatment versus.
@ASTRO_org
ASTRO
24 days
New in #practicalRO: Three-Dimensional Radiation Therapy for Early Stage Glottic Cancer Using a 4-Field Technique. #radonc
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@DavidSherMD
David Sher
24 days
There are several limitations to the study. It kills me this wasn't placebo-controlled, but at least the mucositis evaluator was blinded, and there was an objective component to the grading (beyond pain). Oral cavity dosimetry is obviously very different for non-NPC patients,.
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@DavidSherMD
David Sher
24 days
The median swallowing score was also superior in the mupirocin group at the end of radiation (33.3 vs. 8.3). Patients also reported less severe pain, both in terms of the score distribution as well as less severe pain (2.4% vs. 26.5%) at the conclusion of radiation:
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@DavidSherMD
David Sher
24 days
Second, from a mucositis standpoint, HOME RUN:
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@DavidSherMD
David Sher
24 days
The results were impressive. First, from a colonization standpoint, nasal mupirocin improved BOTH nasal AND oral colonization with S. aureus.
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@DavidSherMD
David Sher
24 days
176 patients were randomized between mupirocin versus SOC (no placebo), where it was placed intranasally BID for 5 days in a row, then a week break, then 5 days in a row, etc. It started a few days before radiation, and the cycles ended when RT was over. There was one blinded.
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@DavidSherMD
David Sher
24 days
Fascinating phase III trial of nasal mupirocin to reduce oral mucositis (OM) in patients receiving radiotherapy (almost all CRT) for NPC. Staph aureus growth on treatment has been implicated in oral mucositis, and we know that probiotics seem to be effective.
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@DavidSherMD
David Sher
27 days
RT @BadiyanMD: I love working at @UTSW_RadOnc @utswcancer! Such an amazing team here!.
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@DavidSherMD
David Sher
1 month
We are excited that our most recent amendment was approved, streamlining imaging criteria for enrollment. EA3211 is a phase III randomized trial comparing consolidative radiotherapy plus pembro with pembro alone in patients with oligometastatic head and neck cancer who have not.
@eaonc
ECOG-ACRIN Cancer Research Group
2 months
#ClinicalTrial EA3211, led by @DavidSherMD of @utswcancer, aims to improve results for patients with #HeadAndNeckCancer that has spread to a limited number of places. Learn more:
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@DavidSherMD
David Sher
1 month
RT @UTSW_RadOnc: Dr. @MHLinPhD presented, "Report on Common Clinical Workflows and Staffing Models for CTgART," in the session of "Staffing….
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