David Petrik
@DavidPetrik77
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Neurogenesis, neuroscience, stem cell, science, research, Cardiff University
Cardiff, Wales, United Kingdom
Joined December 2020
Mitochondrial dysfunction drives cellular senescence: Molecular mechanisms of inter-organelle communication; https://t.co/q7aRxwNOo2
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Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis. Learn more in this week's
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The neuron–astrocyte metabolic unit as a cornerstone of brain energy metabolism in health and disease
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#Incretin hormones—glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)—act as a critical link connecting digestion, metabolism, and cardiovascular function, supporting physiological adaptations to nutrient intake https://t.co/6Vaei6pUqb
#GLP-1 #GIP
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2025 Nobel Prize for Physiology and Medicine goes to the discovery of Treg immune cells. Well done. Congrats to Drs. Brunkow, Ramsdell and Sakaguchi.
nobelprize.org
The Nobel Prize in Physiology or Medicine 2025 was awarded jointly to Mary E. Brunkow, Frederick J. Ramsdell and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"
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BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
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More great neuroscience talks at CU Biosciences from @ZoltanMolnar64 Mark Hubener, Sonja Hofer @CUBiosciences
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A great symposium on thalamocortical networks, celebrating the research of Frank Sengpiel and Vincenzo Crunelli. Speakers Annette Dolphin, Stuart Hughes, Rhein Parri, Natalie Letesche @CUBiosciences @CactusFrankS
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Acute exercise doesn’t just stress muscles; it reshapes the gut. 🧬🏃♂️ Even one workout transiently rewires gut microbial activity, hinting at a mechanistic link between exercise, microbiota, and host performance. A review in Experimental Physiology shows a single bout of
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Our team is excited and honored to see our new method, HT SpaceM, for high-throughput single-cell metabolomics published in Cell! https://t.co/OEgNiEHgib 👇
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Heart contractility doesn’t just pump blood; it shapes development. This study shows that the physical force of a beating heart switches on a key gene (id2b) that helps build heart valves and supports healthy heart function. https://t.co/QgRDoPQLF8
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This Resource paper introduces an approach to build connectomes from light microscopy-based reconstructions of mouse neurons and inferred synaptic connections. @hanchuanpeng
https://t.co/GRGUHCKq6N
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The gut-brain axis is a bidirectional communication network between the gastrointestinal tract and the central nervous system. This dynamic system integrates neural, endocrine, immune, and metabolic signals, many of which are modulated by the gut microbiota. 🧠 1. Neural Pathway
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breaking down how hormones like GLP-1 & ghrelin team up with neural pathways to control hunger & energy balance. https://t.co/flu7xjRcBl
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A new paper from our lab: we show for the first time that anti-obesity medications do NOT change the proportion of anorexigenic neurons both in mice and human iPSC-derived neurons
journals.plos.org
Anti-obesity medications (AOMs) have become one of the most prescribed drugs in human medicine. While AOMs are known to impact adult neurogenesis in the hypothalamus, their effects on the functional...
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Enjoyed this session and learning from the other speakers. Clearly the hypothalamus is highly plastic in adult and major questions re: stem cell populations remain. Exciting progress. #hypothalamus
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