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William A. Wallace, Ph.D. Profile
William A. Wallace, Ph.D.

@drwilliamwallac

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• Scientist | Director, Product Development & Scientific Affairs • R&D | Innovation Strategy | Formulation | Regulatory • Health Educator

Roanoke, VA
Joined October 2014
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@drwilliamwallac
William A. Wallace, Ph.D.
14 hours
Melatonin has known antioxidant properties in the brain and in the gut. More recently, it has been suggested the same can be said about its protective effects in skeletal muscle. Of note, this post is not meant to outline or suggest generalized protocols regarding supplemental
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@drwilliamwallac
William A. Wallace, Ph.D.
19 hours
Nutritional Neuroscience: Micronutrients in Neurotransmitter Synthesis and Metabolism- A Simple Illustration. Understanding the complex interplay between vitamins, minerals, and neurotransmitter pathways highlights the foundational role of nutrition in cognitive health and
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@drwilliamwallac
William A. Wallace, Ph.D.
2 days
Magnesium isn’t just important, it’s essential for life. Magnesium is indispensable for cellular function, serving as a counterion (an ion with an opposite charge that stabilizes another ion or molecule.) to ATP, the molecule that powers nearly all biological processes. In this
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@drwilliamwallac
William A. Wallace, Ph.D.
2 days
Creatine - therapeutic applications beyond athletic performance. Creatine, a well-established ergogenic aid in sports, is now being investigated for its potential therapeutic applications in various medical domains, including neuropsychiatric disorders, heart failure, etc.
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@drwilliamwallac
William A. Wallace, Ph.D.
3 days
The multifaceted impact of exercise beyond only skeletal muscle adaptations: the systemic metabolic benefits of physical activity. Regular exercise has emerged as a known regulator of insulin sensitivity and systemic metabolism, mitigating the risk of chronic metabolic diseases
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@drwilliamwallac
William A. Wallace, Ph.D.
4 days
11 Evidence-based Health Benefits of Blueberries:. 1) Nutrient-rich - 150g portion can supply 1/4 of vitamin C and manganese requirements, 1/3 of vitamin K1 needs, and also provide vitamin E and copper. 2) Support gut health - antioxidants and fiber in blueberries both support
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@drwilliamwallac
William A. Wallace, Ph.D.
4 days
A 2022 study (PMID: 36272396) published in Sleep Medicine Reviews showed the negative effects of acute and “chronic” sleep deprivation on muscle protein synthesis, hormonal balance, and metabolic health. Study & Findings:. 🟩 One night of total sleep deprivation:. - Muscle
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@drwilliamwallac
William A. Wallace, Ph.D.
5 days
A recent study (PMID: 39861452) looked at the association between egg consumption and all-cause mortality in a large cohort of adults. The findings suggest that moderate egg consumption is linked to reduced mortality risk. Findings:. ✅ Eating eggs 1-6 times per week was
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@drwilliamwallac
William A. Wallace, Ph.D.
5 days
In this episode of Daily Value, we evaluate the often-overlooked yet powerful connection between your gut microbiome and vitamin absorption. Going beyond basic nutrition, we’ll break down how gut bacteria directly influence your body's ability to synthesize and efficiently absorb
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@drwilliamwallac
William A. Wallace, Ph.D.
5 days
The current European and American recommendations concerning physical activity indicate:. *150 min per week of moderate physical exercise (30 min/day, 5 days/week).or.*75 min/week of physical exercise of vigorous intensity (15 min/day, 5 days/week). *Practicing physical exercise
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@drwilliamwallac
William A. Wallace, Ph.D.
6 days
A recent 2025 meta-analysis (PMID: 40327515) of five randomized controlled trials found that alpha lipoic acid [ALA (a mitochondrial-derived antioxidant)] significantly improved sperm motility and morphology in men with idiopathic infertility. 📈 Findings (600 mg/day for ~3
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@drwilliamwallac
William A. Wallace, Ph.D.
6 days
1). Approximation of zinc distribution in the body per respective tissues/organs. 2). Conditions associated with deficiencies. Zinc Content in Body:.*Muscle: ~49.5%.*Bone: ~36.7%.*Liver: ~3.4%.*Skin: ~4.2%.*Whole blood: ~1.5%. Conditions Associated with Zinc Deficiency:.*Brain:
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@drwilliamwallac
William A. Wallace, Ph.D.
6 days
Summary of causes of magnesium deficiency and diseases and disorders associated with magnesium deficiency. Note: not all diseases associated with magnesium deficiency are a direct cause of magnesium deficiency. Magnesium deficiency can be a byproduct of disease/condition or
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@drwilliamwallac
William A. Wallace, Ph.D.
7 days
Importance of creatine metabolism in whole-body physiology. The creatine/phosphocreatine system is essential for the chemo-mechanical energy transduction of cells/tissues with high, fluctuant, and constant energy demands. This post is focused on the modes through which creatine
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@drwilliamwallac
William A. Wallace, Ph.D.
7 days
This is the first large RCT showing that vitamin D3 may help preserve biological aging markers. Recent research (PMID: 10.1016/j.ajcnut.2025.05.003) from the VITAL randomized controlled trial found that daily supplementation with 2,000 IU of vitamin D3 over four years
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@drwilliamwallac
William A. Wallace, Ph.D.
7 days
Myokines are a specialized subset of peptides (acting as signaling molecules) produced by muscle fibers in response to exercise. These molecules have emerged as pivotal players in the crosstalk between muscle and various organ systems. The scope of myokine action extends across
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@drwilliamwallac
William A. Wallace, Ph.D.
8 days
A recent systematic review published in GeroScience highlights the multifaceted effects of glycine on various human physiological systems. The review consisted of 50 studies (most of which were RCTs) with oral ingestion of glycine being the most common mode of delivery. Trials
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@drwilliamwallac
William A. Wallace, Ph.D.
8 days
For the first time in humans, a study shows supplementation with the popular mushroom, Cordyceps sinensis (500 mg/2x/day) accelerated stem cell recruitment in skeletal muscle post-high-intensity exercise. A randomized, double-blind, placebo-controlled crossover study published
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@drwilliamwallac
William A. Wallace, Ph.D.
9 days
Does carbohydrate timing after exercise matter?. A recent study (PMID: 39263899) looked at how delaying carbohydrate intake post-exercise affects next-day performance in trained male athletes. Participants completed eight intervals at 85% peak power output, followed by a
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