Caroline Bonner
@CBonner_Pasteur
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Group Leader: Institute Pasteur de Lille, U1190 - Translational Research of Diabetes: Unraveling the mechanisms of anti-diabetic drugs☘️🇨🇮
Lille, France
Joined February 2019
[💼JOB ALERT] L'Institut Pasteur de Lille, fondation privée indépendante, reconnue d’utilité publique depuis 1898, recherche sa #directrice générale / son #directeur général. Retrouvez toutes les informations sur le poste👉 https://t.co/jUSs48bMQg
#santé #recherche #prévention
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🧠💊Sharing new work by Ruth Hanssen and @tittgemeyer showing that the GLP1 agonist liraglutide restores impaired associative learning in people with obesity. Online now in @NatMetabolism
https://t.co/VS0GMCtQ2E
nature.com
Nature Metabolism - Hanssen et al. demonstrate that associative learning is reduced when metabolic sensing is impaired in obesity and can be restored by liraglutide.
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#OpenAccess in @CellRepMed Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant #PancreaticCancer
https://t.co/HvMKMFAqRp Metabolomics profiling of pancreatic cancer organoids identifies two subtypes - high glucose
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« Our survey demonstrates that non-native English speakers, especially early in their careers, spend more effort than native English speakers in conducting scientific activities, from reading and writing papers and preparing presentations in English » https://t.co/UwmmUGWBvl
journals.plos.org
This study reveals that non-native English speakers, especially early in their careers, spend more effort than native English speakers in conducting scientific activities, from reading and writing...
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Our lab is hiring postdocs for 3 funded projects on hypothalamic development and function using brain organoids and mice with advanced microscopy, single cell ‘omics, in utero electroporation. If interested, pls email your CV+cover letter to Dr. Kurrasch (kurrasch@ucalgary.ca).
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Online now! Liraglutide restores impaired associative learning in individuals with obesity https://t.co/R6VcayQQun
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Our new review is out, taking a retrospective look at the evolution of dual incretin agonists. We also spend some time discussing if and how GIP matters for new drugs like tirzepatide. @MatthiasTschop @TimoMueller_IDO @Cell_Metabolism
https://t.co/DCWARYnkwB$
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A new review, the dual GIPR-GLP-1R co-agonists exemplified by Tirzepatide move to the front of the stage #T2D #obesity #weightloss @Cell_Metabolism
cell.com
In this review, Campbell et al. discuss the development of multi-receptor therapeutics that target incretin receptors to improve glycemic control and induce weight loss. This is a 20-year perspective...
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SERCA2 deficiency leads to glucose intolerance and reduced proinsulin processing in beta cells via alterations in the spatial regulation of prohormone trafficking and processing enzyme maturation https://t.co/Vl7ccz53SK 🔓
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SGLT2i and GLP-1RA show benefits as adjunct Tx in #T1D w/ SGLT2i providing CV & renal benefits, but w/ ⬆️ risk of DKA & UTI @AlamUazman @LivuniILCaMS @TriNetX @WCMQatar @matt_anson 🔓 https://t.co/cbA6dhJXg0
#TopTweetTuesday
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World’s Most Iconic Graduate School Recommendation Letter: John Nash, a prodigious mathematician known for his groundbreaking work in game theory and other mathematical disciplines, submitted an application to Princeton University’s esteemed mathematics graduate program in 1948.
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Congratulations to Patrik Rorsman FRS - pancreatic islet electrophysiologist extraordinaire! http://t.co/4o37Q3vlgZ
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Focus on the ever-growing evidence of #cardiovascular protection offered by #incretin-based therapies, reviewing CVOTs and real-world data of #GLP-1 receptor agonists and early clinical trials of novel dual and triple co-agonists. #T2D #GLP1RA #CVD. https://t.co/SURUFwXhof 🔓
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VMNdm Ghrh neurons provide complex dynamic, sex-specific input to the brain glucose-regulatory network #hypoglycemia
https://t.co/Tu8Ccefgo5
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The (leaky) gut brain axis enabling neuroinflammation is a reproducible finding in mouse studies. Will these findings yield druggable targets for human disorders? https://t.co/EBZHx7QqRT
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.@Innodiagroup researchers from @LahesmaaGroup & @EloLab_fi demonstrate serum proteomics differences and associations with #betacell function and #type1diabetes in a pan-European study to arrest #T1D
https://t.co/p6YyEZEFB4 🔓
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REVIEW Ozanne, Constancia et al. (@Cambridge_Uni) discuss sex differences in response to pre-conceptual & in utero environments, detailing the mechs underlying #inheritance of metabolic traits & how they can later manifest as metabolic diseases. https://t.co/XnTwkwYyo5
nature.com
Nature Metabolism - Ozanne and colleagues discuss the evidence of sex differences in the response to suboptimal pre-conceptual and in utero environments, detail the biological mechanisms underlying...
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Masterclass 😭 #bestmemeever
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The Central-Versus Peripheral-Mediated Effects of Liraglutide Enhancement on Insulin Secretion is Dependent on the Stage of Diabetes @SSRN @cellpressnews Sneak Peek
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