Jonathan Campbell
@JCampbellLab
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@Diabetes_ADA @AmDiabetesAssn Finally Jon Campbell @DukeMedSchool synthesizes gain and loss of GIPR science, reconciling some contradictions while providing a road map for future mechanistic and clinical science to fill in the gaps #weightloss #obesity
https://t.co/4w1MTHbh3g
@AmDiabetesAssn #diabetes
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The intriguing case for GIPR antagonism, supported by genetics, pharmacology and Maritide is presented by Rosenkilde, George, Veniant and Holst #weightloss ##obesity
https://t.co/BRYzffz2gU
@Diabetes_ADA @AmDiabetesAssn
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As we head to the 2025 @AmDiabetesAssn GIP biology will be part of the conversation. Here Samms and Sloop summarize the compelling scientific story of Tirzepatide and the case for GIPR co-agonism #Diabetes #Weightloss #obesity
https://t.co/M5UMnAsl0w
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We are looking for a postdoc! If you are interested in obesity/type 2 diabetes and extracellular vesicles apply below! https://t.co/aInZylwCgH
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It's a beautiful day in the islet neighborhood - check out our review on paracrine actions of primary cilia: https://t.co/WtJ5wKoAY8
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Get an updated view on the alpha-cell control of metabolism @UTSWNews Obesity, Metabolism & Diabetes Seminar Series! Join @JCampbellLab from @DukeMPI for an insightful lecture. Don't miss out! #centerforhypalamicresearch
@UTSWInternalMed
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New human data investigating the insulintropic actions of glucagon. https://t.co/Ki9OT7mdow
#diabetes
figshare.com
Abstract (186 words)Glucagon is generally defined as a counter-regulatory hormone with a primary role to raise blood glucose concentrations by increasing endogenous glucose production (EGP) in...
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Pretty good article on the issues of bariatric surgery in teens. A few quotes from me.
nytimes.com
If childhood obesity is an ‘epidemic,’ how far should doctors go to treat it?
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Today I presented our unpublished data on new adipocyte genes and got zero feedback - great success!
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https://t.co/syG4uT7TLf Your fat cells listen and talk. Here, you can read about how surrounding stromal cells in adipose tissue are also getting in on the conversation. New review from @jessicacannavi1 @DukeMPI @dukeendocrinol1
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Congratulations to @TimoMueller_IDO on receiving the the 58th Minkowski Prize Lecture Award at #EASD2023 @DiabResearch #HamburgHall for his groundbreaking #research on energy & #glucose #metabolism regulation via GIP and GIPR:GLP-1R co-agonists. 💡👏
The 58th Minkowski Prize Lecture Award #EASD2023 @EASDnews Professor Timo Müller @helmholtz_diabc Novel insights into regulation of energy and glucose metabolism by GIP and GIPR:GLP-1R co-agonists #obesity #diabetes @DiabResearch Hamburg Hall
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Now Dr Erin Mulvihill teaching us about the cardiovascular effects of incretins
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Followed by Prof Fiona Gribble, walking us through the gut production of hormones.
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“Signs of glucagon resistance after a two-week hypercaloric diet intervention” #T2D #Pathophysiology Huge amount of experimental work, facinating results and data-driven conclusions beautifully presented by @MalteSuppli in Hamburg Hall #EASD2023🎯🤩👏🏼 https://t.co/1QN7kmWvTt
Join @Maltesuppli next week in Hamburg #EASD2023 when he presents his abstract "Signs of glucagon resistance after a two-week hypercaloric diet intervention"🤩 https://t.co/LV8KWSWxOa
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Fractyl Health’s GLP-1 gene therapy spurs 25% weight loss in obese mice, clinical trials slated for 2024 -
endpoints.news
One of the biggest problems facing the burgeoning class of weight loss drugs is that people must take them day after day, week after week. When the injections of semaglutide ...
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@Cell_Metabolism @BoyiGan @CamillaScheele @NatMetabolism @NatureMicrobiol @proferikrichter @UCSDMedSchool @UCSanDiego @KnoblochLab @RollingStones @umichmedicine @StJudeResearch @BurcuDarst @fredhutch (17/18) Finally, the list wouldn't be complete without highlighting the review by @JCampbellLab and collaborators on GIPR/GLP-1R dual agonist therapies for #diabetes and #weightloss #BackToMetabolism @DukeU @dukemedicine @DiabResearch @helmholtz_diabc
cell.com
In this review, Campbell et al. discuss the development of multi-receptor therapeutics that target incretin receptors to improve glycemic control and induce weight loss. This is a 20-year perspective...
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@Trends_Endo_Met @BoyiGan @CamillaScheele @NatMetabolism @NatureMicrobiol @proferikrichter @UCSDMedSchool @UCSanDiego @KnoblochLab @RollingStones @umichmedicine @StJudeResearch @BurcuDarst @fredhutch @JCampbellLab @DukeU @dukemedicine @DiabResearch @helmholtz_diabc (18/18) Feeling inspired? Let's keep the #BackToMetabolism conversation going! What was your favorite summer paper? Also, if you enjoyed this thread and have an exciting story or review idea to pitch, feel free to reach out to editors @Cell_Metabolism and @Trends_Endo_Met !
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I've enjoyed a lot reading this piece revisiting a seminal article on glucagon physiology. Don't miss "Classics in Diabetes" by @AmDiabetesAssn Amazing how #glucagon, the cinderella hormone, regulate metabolism, and how many questions still unsolved! https://t.co/2nIIdCWs94
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